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School of Medicine awarded $2.6M; receives two of 13 grants nationally

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Using a variety of public records—including assessed market value, sales, foreclosure and tax history, code violations, building permits and rental registry data—the researchers examined every rental property in Cleveland from 2016-18 on factors related to the likelihood that the property could have lead-safety problems.

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Brain cell dysfunction in low oxygen is, surprisingly, caused by the very same responder system that is intended to be protective, according to a new published study by a team of researchers at the Case Western Reserve University School of Medicine.

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While most of the global effort to contain COVID-19 focuses on its continuing human cost, a team of researchers has formed to focus on protecting the next potential wave of virus victims: wildlife.

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Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.

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Researchers at Case Western Reserve University School of Medicine seek to optimize emerging methods of diagnosing two common neurodegenerative diseases—dementia with Lewy bodies and Parkinson’s disease dementia—which affect 1.4 million in the United States

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Within a few months, federal officials reported that one of every five nursing homes had experienced a death from the novel coronavirus. Not long after, several media outlets published independent analysis finding that an estimated 40% of the fatalities related to COVID-19 took place in nursing homes. Rather than surrender to the terrifying trend, Case Western Reserve researchers saw an opportunity to help.

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Mouth lesions are among the main early indicators of oral cancer, but determining whether a sore is actually malignant typically involves painful, costly biopsies. Case Western Reserve researchers think they have a better idea—and the National Institutes of Health has given them $420,000 to advance it.

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The developers of Case Western Reserve University’s signature HoloAnatomy mixed-reality software for the Microsoft HoloLens knew they were likely achieving a global first this Spring when they quickly pivoted to the first-ever, all-remote anatomy course when the COVID-19 pandemic kept 185 first-year medical students from coming to campus. Now, they have data reporting that an overwhelming majority of those students across the U.S. and Canada not only preferred the remote course, but believe they can effectively learn anatomy via the mixed-reality application.

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A team led by researchers from Case Western Reserve University School of Medicine and Cleveland Clinic Lerner Research Institute has secured $10.4 million over five years from the National Institutes of Health/National Cancer Institute to explore at the molecular level the differences in glioblastoma between males and females.

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esearchers at Case Western Reserve University have added to the growing body of understanding about how hydroxychloroquine (HCQ) is not a possible defense against COVID-19. Specifically, they found that HCQ is not effective in preventing COVID-19 in patients with lupus and rheumatoid arthritis (RA), suggesting a broader interpretation of HCQ as ineffective preventive medicine for the general population. Their findings were recently published in the Annals of the Rheumatic Diseases.

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A new five-year agreement awards $5.4 million (with the potential for up to $11 million) to a team led by Case Western Reserve, and includes a subcontract to PolymerPlus LLC, a Cleveland-based polymeric development company founded at the university in 2010, to lead production scale-up.

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Cleveland – Researchers at Case Western Reserve University reviewed national data from the U.S. Census Bureau and found associations between states’ voting patterns in the 2016 presidential elections and decreases in the number of adults 18 to 64 years of age without health insurance coverage.

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Research has found that those living with HIV have a higher risk for certain kinds of cancers—such as lung cancer. Now, with a new five-year, $3.7 million grant from the National Cancer Institute, researchers from Case Western Reserve University hope to find out why.

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A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children. It results from genetic mutations that prevent the body from properly making myelin, the protective insulation around nerve cells.

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Prof. Jonathan Adler's research and writing on the Affordable Care Act is credited with inspiring litigation that led to a Supreme Court challenge to the lawfulness of tax credits in states that failed to create their own health insurance exchanges.

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Medtronic, a global leader in medical technology, has committed $1 million over five years to fund an endowed professorship at the Case Western Reserve University School of Medicine.

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Nursing researchers and planners at Case Western Reserve University, funded by a new three-year, $2.44 million John A. Hartford Foundation grant, will work with CVSHealth and the Institute for Healthcare Improvement to integrate into 1,100 CVS MinuteClinic locations the signature "Age-Friendly" approach developed by the foundation and institute. They will incorporate the age-friendly concepts into day-to-day care for older adults and track their implementation at all retail locations.

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A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure.

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Black patients with one of the deadliest forms of skin cancer are likely to experience a longer delay from diagnosis to surgery than non-Hispanic white (NHW) patients, according to a new study published in the Journal of the American Academy of Dermatology.

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The COVID-19 pandemic could inflict long-lasting emotional trauma on an unprecedented global scale, leaving millions grappling with debilitating psychological disorders, according to a new study commissioned by an interdisciplinary team of researchers from Case Western Reserve University.

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A clinical researcher, who has studied the lack of hygiene practices among hospital patients, is urging not just hospitals—but those who end up there—to do more to fight against the novel coronavirus, which had infected more than 2 million people worldwide by mid-April.

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A new $6 million, 5-year grant from the National Institutes of Health extends funding for the Silvio O. Conte Cleveland Digestive Diseases Research Core Center (DDRCC), a cross-institutional collaboration of digestive disease investigators.

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For the first time, instead of working together on campus, all 185 first-year students from Case Western Reserve University’s School of Medicine are using Microsoft HoloLens and the university’s signature HoloAnatomy mixed-reality software, despite the physical separation created by the COVID-19 pandemic.

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The National Heart, Lung, and Blood Institute (NHLBI) has awarded Case Western Reserve University up to $3.7 million to assess emerging genome-editing based therapies being tested for curing sickle cell disease (SCD) at leading U.S research universities and hospitals. SCD is the most well-known among a group of inherited blood disorders, affecting about 100,000 people in the United States and about 20 million worldwide, according to a 2018 National Institutes of Health (NIH) statement announcing the NHLBI Cure Sickle Cell Initiative.

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A team of scientists, including Case Western Reserve University chemistry Professor Blanton Tolbert and his research lab, are conducting the underlying research to develop an antiviral to slow the spread of novel coronavirus that causes COVID-19.

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The Inamori International Center for Ethics and Excellence at Case Western Reserve University will award Judge Silvia Alejandra Fernández de Gurmendi.

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Physician burnout is a growing concern within the profession, but it’s also a public-health. Now, in new published research, a Case Western Reserve University law professor insists that government—not just the medical profession—needs to step up to address the problem.

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Displaced workers experienced a 20% increase in criminal charges the year after being laid off

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Nearly 94% of defendants in Cuyahoga County drug court have been exposed to trauma and many suffer from symptoms of post-traumatic stress disorder (PTSD), according to a new Case Western Reserve University study.

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Researchers at Case Western Reserve University, funded in part through a Gund-Harrington Scholar grant at University Hospitals in Cleveland, have used used chemically modified lipids—instead of the viruses most commonly used as carriers— to safely deliver gene therapy to fight a rare, but irreversible, genetic eye disorder known as Stargardt disease.

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A new study by researchers at Case Western Reserve University examines how lawmakers could improve guidelines and policies to keep animal abusers from slipping through the cracks. Researchers also zeroed in on the well-established link between animal abuse and interpersonal violence.

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Imagine a future in which every consumer purchase is as complex as choosing a mobile phone. What will ongoing service cost? Is it compatible with your other devices? Can you move data and applications across devices? Can you switch providers? These are among the questions one must consider when a product is “tethered”—or persistently linked—to the seller. They’re also questions posed by Aaron Perzanowski, a law professor at Case Western Reserve University, in a recent article.

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In addition to the mental and emotional toll of uprooting families to find stable, affordable housing, children facing eviction are at a higher risk for lead exposure and poorer outcomes in the classroom, according to new research from the university’s Jack, Joseph and Morton Mandel School of Applied Social Sciences.

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A new drug that could make it easier for doctors to diagnose multiple sclerosis (MS) in its earlier stages has been approved for its first human trials by the U.S. Food and Drug Administration (FDA).

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A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real time with patients at Cleveland Clinic under a three-year, $600,000 V Foundation grant.

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One in five children in Cuyahoga County, Ohio, are either exposed to, or are victims of, violence and trauma, according to a new study from the Jack, Joseph and Morton Mandel School of Applied Social Sciences at Case Western Reserve University.

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With a $2.75 million, three-year grant from the Bristol-Myers Squibb (BMS) Foundation, researchers from Case Western Reserve University will lead a community wide initiative to create and apply innovative methods to prevent and detect lung cancer in underserved residents in Northeast Ohio.

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Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn’s disease (CD).

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Case Western Reserve University will soon offer free energy-efficiency assessments to qualifying manufacturing companies and water treatment plants in an industrial belt spanning parts of three states—including Northeast Ohio, some of the lower peninsula of Michigan and Western Pennsylvania. The energy assessments could save up to 15-20% on energy costs at the average industrial plant, said Chris Yuan, director of the new U.S. Department of Energy (DOE) Industrial Assessment Center at Case Western Reserve. More information about the center, including details on how to apply for a free assessment, can be found through its online portal.

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Case Western Reserve University has launched a new Computer & Data Sciences Department in the Case School of Engineering (CSE) and announced the Kevin J. Kranzusch Professorship, which will be held by the future chair of the new department. The new department was made possible primarily with a $5 million gift from Kranzusch, a CSE alumnus, who said a spike in computer sciences enrollment, coupled with the advent of Artificial Intelligence (AI), inspired him to make the commitment.