The findings, published in The Laryngoscope, show that only 1 in 7 subsequently needed surgery for injuries that weren’t resolved with vocal therapy and other conservative management. Researchers determined which vocal injuries were most common by sex, age, training, and professional/amateur status, and what kinds of treatment these patients subsequently required.
The National Academy of Sciences (NAS) today elected UT Southwestern scientist Jonathan Cohen, Ph.D., into its membership, one of the highest honors for American scientists. Dr. Cohen, Professor of Internal Medicine in the Center for Human Nutrition and the Eugene McDermott Center for Human Growth and Development at UT Southwestern, was elected by his peers in recognition of distinguished and continuing achievements in original research. His research centers on identifying genes that play major roles in the metabolism of cholesterol and triglycerides and elucidating the biological roles of their protein products.
For years, women recovering from cesarean section (C-section) deliveries have been given devices that let them, with a button, control the flow of opioid painkillers into their IV line. But as researchers and policymakers push to curb the use of opioids, clinicians are developing new strategies for treating pain after C-sections.
UT Southwestern Medical Center is ranked as the top health care employer for diversity in the U.S. and among the top 20 across all industries, according to America’s Best Employers for Diversity 2022 list compiled by Forbes and Statista. UT Southwestern is the only health care institution listed among the top 20 employers nationally.
Women who were pregnant during the recent Omicron surge were diagnosed with COVID-19 at a much higher rate than during previous phases of the pandemic, but were less likely to develop severe illness, a study by UT Southwestern and Parkland Health scientists found. The research, reported in JAMA, is the first published evidence documenting how the boom in COVID-19 cases late last year and early this year impacted the health of pregnant women.
UT Southwestern Medical Center is among the Top Producing Institutions of 2021-2022 Fulbright Students in the U.S., and one of the top producers of U.S. Fulbright students among 4-year, special-focus institutions.
The National Institutes of Health (NIH) and the National Institute on Aging recently approved funding for a 2022 study by the Institute for Exercise and Environmental Medicine (IEEM), where a research team will look into how body weight – even extra weight gain like the kind recently resulting from the COVID-19 pandemic – may adversely affect breathing in seniors.
Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study. The findings, published in Nature, could lead to new ways of manipulating STING to prompt stronger immune responses or stem its action in autoimmune diseases.
Cellphone “selfies” distort facial features, an effect that may be driving an uptick in requests for plastic surgery, UT Southwestern researchers show in a new study. The findings, reported in Plastic and Reconstructive Surgery, highlight an unexpected consequence of social media and the need for plastic surgeons to discuss this phenomenon with their patients.
UTSW scientists identify key molecule produced by male parasitic worms that affects sexual maturity in females and leads to schistosomiasis
Babies and toddlers who need a tracheostomy – a tube surgically inserted into their windpipe to help relieve breathing problems – are at a high risk of accumulating fluid behind their eardrum when on a ventilator. That’s the conclusion of a new study, published in the International Journal of Pediatric Otorhinolaryngology, by UT Southwestern head and neck surgeons. This buildup of fluid, called a middle ear effusion, can put them at risk for ear infections, hearing loss, and delays in speech and language development.
UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes – organelles that serve as protein factories for cells – as well as a surprising part in neurodevelopmental disorders. These findings, published in Cell Reports, could lead to new ways to manipulate ribosome production, which could impact a variety of conditions that affect human health.
The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues. The article, published in Nature Cardiovascular Research, argues for more research into this root cause to develop truly effective treatments.
More than 200 UT Southwestern medical students matched to more than 80 programs across the nation, including Harvard, Yale, and Johns Hopkins, as well as a dozen medical programs across Texas.
The PGA of America and Omni Hotels & Resorts today announced a new six-year partnership with UT Southwestern Medical Center, naming the hospital as the “Official Healthcare Partner of PGA Frisco.” The relationship will begin in 2023, to coincide with the official opening of PGA Frisco and Omni PGA Frisco Resort.
Cognitive decline is the biggest factor in determining how long patients with Alzheimer’s disease will live after being diagnosed, according to a new study from researchers at UT Southwestern. The findings, published in the Journal of Alzheimer’s Disease, are a first step that could help health care providers provide reliable prediction and planning assistance for patients with Alzheimer’s disease and their families.
To meet growing demand for primary and preventive health care in Fort Worth, Tarrant and surrounding counties, UT Southwestern Medical Center has launched a new primary care clinic in the UT Southwestern Monty and Tex Moncrief Medical Center at Fort Worth.
A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study. The findings might someday lead to a way to regenerate brain tissue after disease or injury.
Diagnosing heart attacks after heart surgery remains difficult due to shortcomings of current diagnostic tools when applied to postoperative patients, including the electrocardiogram and blood tests to detect levels of cardiac troponins, according to an editorial in the New England Journal of Medicine (NEJM) written by two UT Southwestern faculty members.
UT Southwestern Medical Center is pleased to announce a $100 million gift from the O’Donnell Foundation to endow and support its new School of Public Health. This investment is the largest gift to a School of Public Health at a public university in the U.S. and matches the third largest gift supporting any School of Public Health.
In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body’s organs and increases the risk of early death from heart or liver disease. In 2001, a transmembrane protein called seipin was identified as a molecule essential for proper fat storage, although its mechanism has remained unknown.
COVID-19 patients who receive a palliative care consultation are 5.6 times more likely to receive comfort care at the end of life and are just as likely to receive CPR if needed as those who did not receive a consultation, according to a UT Southwestern study.
Patients with both a high lipoprotein(a) and high coronary artery calcium score (CAC) face a more than 20% risk of heart attack or stroke over the following 10 years, according to findings from a multicenter study led by preventive cardiologists at UT Southwestern Medical Center.
Blood pressure rose moderately during the early months of the pandemic, according to a UT Southwestern study of patients who monitored themselves at home.
UT Southwestern Medical Center has completed a five-year, $1 billion campaign to fuel its commitment to advance brain research and clinical care at its Peter O’Donnell Jr. Brain Institute, making it one of the largest brain-focused investments at a U.S. academic medical center.
Changes in habits during the pandemic can lead to unexpected health issues with feet and ankles. Orthopedic surgeon Kshitij Manchanda, M.D. at UT Southwestern Orthopaedic Surgery and Sports Medicine has seen an increase in both reported injuries and chronic problems.
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UT Southwestern Medical Center is one of the 10 best large employers in the United States and among the top 5 health care employers, according to the America’s Best Employers 2022 list compiled by Forbes and Statista.
Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows. The results run counter to the common practice of withholding the clot-busting drug to these patients due to concerns over complications from bleeding.
Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.
Samuel Achilefu, Ph.D., nationally recognized for expertise in molecular imaging and its application in treating human diseases, has been selected inaugural Chair to launch a new Department of Biomedical Engineering (BME) at UT Southwestern Medical Center. He begins his new responsibilities Feb. 1.
A new approach that targets the cellular machinery that viruses need to reproduce – rather than the virus itself – appears to stem replication of a common childhood pathogen known as respiratory syncytial virus (RSV), UT Southwestern researchers report in a new study. The findings, published in Scientific Reports, could offer a novel strategy to fight this virus and others, including SARS-CoV-2, the virus responsible for the ongoing COVID-19 pandemic.
UT Southwestern structural biologist and neuroscientist Ryan Hibbs, Ph.D., has received a 2022 Norman Hackerman Award in Chemical Research. The prize recognizes his work investigating the structure and function of receptors on the surfaces of brain cells and how they interact with drugs, such as nicotine or general anesthetics.
Physician researchers from UT Southwestern Medical Center have developed an innovative nanotherapeutic drug that prevents cancer from spreading to the liver in mice.
Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study. The findings, published in Cell Metabolism, highlight metabolic vulnerabilities in malignant cells that could eventually lead to new cancer therapies.
A novel study by UT Southwestern researchers who conducted interviews as the nation shut down due to COVID-19 tells the stories of those who routinely faced hunger before the pandemic upended their lives. The research, which could be used to improve the response in future emergencies, finds food pantry clients experienced increased economic hardship, food insecurity, and psychological distress.
A first-in-kind immune-modulating drug that arose from decades of basic research at UT Southwestern Medical Center has received approval from the U.S. Food and Drug Administration as a new treatment for adults with a form of myasthenia gravis. This rare and chronic autoimmune disease is characterized by debilitating and potentially life-threatening muscle weakness.
What if the key to aging well lies in reprogramming immune system cells to strengthen them against infections and cancer? Researchers at UT Southwestern are working to find out.
Researchers at UT Southwestern Medical Center studied outcomes for young women at a county hospital and found that while 97% of them accessed prenatal care, those with greater social needs were associated with adverse outcomes both during pregnancy and during the early weeks of their babies’ lives. The differences persisted even after adjusting for age, race, and body mass index.
Combining two agents to block a parasitic worm’s life cycle boosted survival from a potentially deadly tropical disease to 85% in animal models, far better than either treatment alone, according to a proof-of-concept study led by UT Southwestern Medical Center pharmacologists.
A subtle smile emerged on Dr. James Leidner’s face as he envisioned telling people of the unusual contribution he made to mankind’s mission to Mars.
In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer’s disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain.
Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.
The Harold C. Simmons Comprehensive Cancer Center has been awarded grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to increase minority participation in clinical trials, expand lung cancer screening, develop brain tumor drugs, and advance innovations in drug discovery and technology.
A study involving UT Southwestern neurology researchers found lower-quality outcomes for Hispanic ischemic stroke patients who receive endovascular thrombectomies than for comparable white and Black patients.
UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study, published in Science, identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights into the ways pairs or groups of proteins fit together to carry out cellular processes could lead to a wealth of new drug targets.
Ground has been broken for construction of a new building that will catalyze a unique partnership between UT Southwestern Medical Center and UT Dallas, bringing their biomedical engineering programs together to foster innovative solutions for unmet medical needs.
The outcome predictive models were developed in part using data from a large multi-center National Institute of Mental Health-funded study and published in the journal Biological Psychiatry. The findings provide strong evidence that the current trial-and-error approach used in clinical practice for the selection of the right antidepressant can be replaced with this new precision medicine approach.
Blocking a molecule that draws sensory nerves into musculoskeletal injuries prevents heterotopic ossification (HO), a process in which bone abnormally grows in soft tissue during healing, UT Southwestern researchers reported in a study. The findings, published in Nature Communications, suggest that drugs currently being tested in clinical trials to inhibit this molecule for pain relief could also protect against this challenging condition.
UT Southwestern Medical Center has been selected as a Rare Disease Center of Excellence – charter members of an elite network of 31 centers nationally to expand access, and advance care and research for rare disease patients in the United States.
New findings by UT Southwestern researchers help better understand the how one of the most commonly mutated genetic drivers of cancer passes signals that cause the disease.
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