Newswise — Laszlo Otvos, Jr., MD, research professor and director of drug development for the Sbarro Institute for Cancer Research and Molecular Medicine (http://www.shro.org), has published one of the "Most Cited Articles: 2006" according to ACS Publications.

"Relaxin-3: Improved Synthesis Strategy and Demonstration of Its High-Affinity Interaction with the Relaxin Receptor LGR7 Both In Vitro and In Vivo," originally appeared in the journal Biochemistry.

The recognition is based on citation data obtained from Thomson ISI and awarded for articles that cover "research of immediate interest.

In 2001, a paper published by Otvos in the same journal was cited as a "Hot Paper." The designation recognizes papers that may signal important new trends in research and serve as leading indicators of new scientific advances.

The Sbarro Health Research Organization (www.shro.org), located in Philadelphia, Pennsylvania (USA), is a nonprofit organization that finances and promotes the work of established researchers and young scientists in medicine, molecular biology, genetics, physics, chemistry and biomathematics. SHRO funds the Sbarro Institute of Cancer Research and Molecular Medicine located at Temple University in Philadelphia, PA and a lab in Siena, Italy.