June 17, 1999

Smokeless Tobacco Users Wanted for Research Project

ROCHESTER, MINN. -- Mayo Clinic researchers are looking for people who use snuff or chewing tobacco to test the effectiveness of an experimental program aimed at helping smokeless tobacco users quit.

Participants will receive counseling specifically designed for smokeless tobacco users. They also will receive either bupropion (otherwise known as Zybanô), an anti-depressant that has been shown to help smokers quit, or a placebo (inactive substance).

Use of snuff and chewing tobacco is associated with cancer of the mouth, esophagus and stomach, heart disease and ulcer disease. More than 5 percent of adult American males use smokeless tobacco products; in Minnesota, the prevalence is almost 10 percent.

"We are hoping to learn more in this study about how smokeless tobacco users differ from smokers in terms of their motivation and what works to help them quit," says Dr. Lowell Dale of the Mayo Clinic Nicotine Dependence Center.

The study will last six months. Anyone interested in participating in the study should call the Mayo Clinic Nicotine Research Center at 1-800-848-7853 or locally, 507-266-1944.

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Mike O'Hara 507-284-9522 (days) 507-284-2511 (evenings) [email protected]