A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two clinical trial conducted by UT Southwestern Medical Center.
Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltrate that cancerous fortification and deliver these drugs could aid treatment for pancreatic cancer, according to newly published findings from a team of University of Wisconsin–Madison researchers.
A new perspective paper explores the current state and future directions of precision medicine in colorectal cancer (CRC). It outlines advancements in molecular testing and their implications for targeted and immunological therapies in CRC.
Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that target cellular metabolism.
Four proposed state-of-the art image search engines for automating search and retrieval of digital histopathology slides were found to be of inadequate performance for routine clinical care. Some had less than 50% accuracy, which is not suitable for clinical practice.
The Angeles Clinic and Research Institute, an affiliate of Cedars-Sinai Cancer, is teaming up with the AIM at Melanoma Foundation for the 14th year to host a free melanoma symposium for patients, caregivers and clinicians.
Physician-scientists from the Department of Urology at Cedars-Sinai will be attending the American Urological Association (AUA) Annual Meeting May 3-6 in San Antonio, Texas, and are available to discuss the latest research and innovations in urological care.
Patients in South Florida with metastatic melanoma will soon have access to tumor-infiltrating lymphocyte therapy, or TIL. The therapy will be available at Sylvester Comprehensive Cancer Center and will be South Florida’s only center offering this treatment.
Sharon Dent, Ph.D., professor of Epigenetics and Molecular Carcinogenesis at The University of Texas MD Anderson Cancer Center, has been elected to the National Academy of Sciences (NAS). Dent is a global leader in the field of chromatin research whose foundational work has helped define the role of chromatin in cancer growth and development.
Connecticut Magazine released its “Top Doctors” issue today, listing some of the state’s best physicians, who provide exceptional care for patients. This year’s list includes 109 Yale Cancer Center (YCC) and Smilow Cancer Hospital (SCH) physicians, a 35% increase in “Top Doctors” for SCH and YCC from last year.
A research team from Tufts University School of Medicine and Massachusetts General Hospital is now reporting evidence that hillocks and their stem cells are physiologically distinct from other cells within the lung and consist of a stratified outer layer of scale-like squamous cells that protect an underlying layer of rapidly expanding basal stem cells that are capable of restoring airway tissue after injury.
Results of a new clinical trial published in Nature Medicine show that a novel, personalized neoantigen vaccine therapy demonstrated promising anti-tumor efficacy in patients with liver cancer who failed their original front-line treatment. The foundational biomedical research leading to this important study and important outcome originated from research in the Vaccine & Immunotherapy Center at The Wistar Institute.
International collaboration to improve cancer outcomes in Sub-Saharan Africa is working to update consensus harmonized guidelines on several key subjects in oncology, including how best to treat people with both cancer and HIV.
The University of Texas MD Anderson Cancer Center and the Pan American Health Organization (PAHO) today announced the signing of an agreement to strengthen cancer prevention and control initiatives across the Americas. The event took place in Washington, D.C., with leaders from both organizations.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for April 2024.
A team led by a Houston Methodist physician established a hypothesis that the microenvironments of tumors in the pancreatic head versus the body and tail, particularly the immunotherapy receptors found on each section of the pancreas, differ. This could impact the way cancer of the pancreas is treated.
Hackensack Meridian Mountainside Medical Center is proud to announce the successful completion of its first bronchoscopy procedure using the Ion Endoluminal System, a cutting-edge robotic-assisted technology designed for minimally invasive lung biopsies.
Ann & Robert H. Lurie Children’s Hospital of Chicago is pleased to announce the first pediatric use of the novel fluorescent agent CYTALUX during surgery to remove lung metastases. The drug allows surgeons to better visualize cancer in the lung, as well as potentially detect additional cancerous nodules missed by preoperative imaging.
Drs. Kachikis and Eckert stressed that more research and funding are needed, specifically in treatments that might help women remain pregnant while fighting cancers and other diseases.
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