The U.S. Food and Drug Administration approved the use of Photofrin(r), a light activated drug used in Photodynamic Therapy, for treatment of patients with early-stage lung cancer.
Roswell Park Cancer Institute will host the first meeting of a Regional Cancer Center Consortium for Biological Therapy of Cancer, February 19-21, in honor of the Institute's Centennial.
The first report of the discovery of inhaled cellulosic and plastic fibers in human lung tissue has been published by researchers at Roswell Park Cancer Institute in the May, 1998 issue of Cancer Epidemiology, Biomarkers & Prevention. The fibers in the human lung may be bioresistant and biopersistent candidate agents contributing to the risk of lung cancer.
Lung cancer is the most common cause of cancer deaths in North America. Innovative technology at RPCI will enable physicians to detect premalignant and preinvasive neoplastic lesions in the lung and initiate appropriate curative treatments such as surgery, radiation therapy, chemotherapy or in many cases, photodynamic therapy using the photosensitzer, Photofrin.
There is no such thing as a "safe" cigarette, concludes Roswell Park Cancer Institute (RPCI) investigators, whose comprehensive analysis of one "safe cigarette" appears in today's issue of Cancer Epidemiology, Biomarkers & Prevention.
Fewer chemotherapy treatments, less intense side effects and fewer visits to the hospital are on the horizon for some pediatric patients. These are the results of an eight-year clinical trial in patients with Wilms' tumor, a cancer of the kidney most often seen in children, published in today's Journal of Clinical Oncology.
A Roswell Park Cancer Institute scientist and Axis Genetics plc., Cambridge, United Kingdom, will collaborate to advance the first edible plant vaccine to protect against hepatitis B virus infection.
A multi-institutional clinical study led by Roswell Park Cancer Institute has demonstrated the safety and effectiveness of a chemoimmunotherapy treatment for patients with non-Hodgkin's lymphoma. The overall response rate was 95% for patients who received treatment with a combination of Rituxan, a monoclonal antibody, and the systemic standard dose chemotherapy regimen used for this disease.
David C. Hohn, MD, President and CEO, Roswell Park Cancer Institute (RPCI), today announced the formation of the Roswell Park Cancer Institute Corporation (RPCIC) and the composition of the RPCIC Board of Directors under the direction of Board Chairman, Mr. Patrick P. Lee, Chairman and CEO of International Motion Control Inc.
Researchers from Roswell Park Cancer Institute (RPCI) are part of an international group studying the long-term health effects caused by the destruction of the nuclear power plant in Chernobyl, Ukraine, April 26, 1986, which exposed thousands to radiation and contaminated farmlands in the Ukraine and Belarus.
The long-term, worldwide trend of increasing breast cancer mortality rates apparently has been reversed in several countries, with significant declines reported in the United States, the United Kingdom and Canada in the 1990s. These are the findings of a study conducted at Roswell Park Cancer Institute and published in the May/June 1999 issue of CA -- A Cancer Journal for Physicians.
Preliminary results of a pilot and a Phase II study using Rituximab to treat non-Hodgkin's lymphoma were presented at the American Society of Clinical Oncology meeting in Atlanta. These studies show Rituximab to be effective when combined with Fludarabine (a chemotherapy) and when used alone dosed in an extended eight-infusion regimen. Both trials were conducted at Roswell Park Cancer Institute and other cancer centers.
Novel genetic factors contribute to the incidence of colorectal cancer among a percentage of African-Americans, according to the results of a pioneering study conducted by a research team headed by Thomas K. Weber, MD, FACS, of the Division of Surgery, Roswell Park Cancer Institute. Their report will appear in the June 23, 1999 edition of the Journal of the American Medical Association.
Roswell Park Cancer Institute (RPCI) and the Boyce Thompson Institute at Cornell University announced that clinical trials will begin today, Wednesday, July 7, 1999, at RPCI, to test the safety and immunogenicity of the world's first potential oral vaccine against the hepatitis B virus.
Roswell Park Cancer Institute scientists have found that the level of gelsolin, a protein responsible for maintaining actin filaments that are needed for healthy cells, may be of diagnostic and therapeutic value for breast cancer.
Roswell Park Cancer Institute is participating in a pilot study to investigate the value of magnetic resonance imaging for the detection of breast cancer in women who are at high risk for the disease. The Consortium received a $6 million National Cancer Institute grant for breast MRI clinical trials.
The first study to evaluate the impact of cardiac disease and second malignant neoplasms on late mortality and to identify risk factors for late mortality among 15-year survivors of cancer diagnosed during childhood or adolescence has concluded that survivors who relapsed during the 15-year period have excess mortality.
Research on colorectal cancer tumors and premalignant polyps, published in the December 21 issue of the Proceedings of the National Academy of Sciences, show that cancer arises from a decade or more of cellular changes.
Amy S. Langer, Executive Director of the National Alliance of Breast Cancer Organizations, will receive the Gilda Radner Courage Award from the Roswell Park Alliance Community Fund-Raising Board at its 10th Annual All Star Night, Saturday, January 22, 2000.
Roswell Park Cancer Institute Corporation has announced two administrative appointments within the Division of Head and Neck Surgical Oncology/Plastic and Reconstructive Surgery.
The lessons from California's aggressive tobacco control intervention program, which has resulted in a continuing decline in adult smoking, may help to decrease adult smoking throughout the U.S., according to a study in the March American Journal of Public Health.
Childhood survivors of Hodgkin's disease have a substantial risk for second malignant neoplasms, according to research published in today's Journal of Clinical Oncology.
Radio frequency ablation is being offered as a treatment option for patients with inoperable tumors by Roswell Park Cancer Institute. RFA may also be used in special cases to treat esophageal, gastrointestinal, testicular, ovarian, neuroendocrine and breast cancers.
With the addition of a new procedure called uterine fibroid embolization, RPCI will expand its services to include treatment of benign fibroid tumors. UFE may preserve fertility by avoiding hysterectomy, particularly in young women with this condition.
Roswell Park Cancer Institute (RPCI) will host a symposium titled, "Molecular Sites of Intervention for Cancer Therapeutics," October 12-13, in Buffalo, NY, to describe and discuss new approaches to the development of cancer therapeutics.
There is a strong push to find methods that may improve survival of Lung cancer by diagnosing the disease at an earlier, presumably more curable, stage. However, whether early detection results in a higher number of cured patients remains unclear. (NEJM, 11-30-00)
The "not so good news" from a recent study conducted at Roswell Park Cancer Institute is that the incidence rates for two forms of common brain tumors - glioblastoma multiforme (GBM) and anaplastic astrocytoma - have increased in New York State between 1976 and 1995. The ìgood newsî is that the study may have revealed clues to the origins of GBM; the most common of these tumors. (Journal of Neurosurgery, 12-00)
A unique pilot initiative created at Roswell Park Cancer Institute was highlighted at the Sixth Annual Conference of the National Comprehensive Cancer Network: "Practice Guidelines and Outcomes Data in Oncology."
Roswell Park Cancer Institute (RPCI) is participating in a multi-center clinical trial to evaluate the benefits and side effects of isolated hyperthermic limb perfusion and melphalan, with or without tumor necrosis factor for patients with advanced melanoma in one of their limbs.
Women who received radiation for a certain type of childhood cancer are at increased risk for complications during pregnancy, and therefore should be carefully assessed and closely monitored by their obstetricians.
The Buffalo Niagara Prostate Cancer Consortium, located at Roswell Park Cancer Institute, is recognized as a national model for patient care by the National Comprehensive Cancer Network and the Oncology Roundtable of the Advisory Board Company. This innovative collaboration, a first in the nation, includes community urologists, academic institutions, patient support groups, insurance carriers and RPCI.
Roswell Park Cancer Institute has initiated two Phase II clinical trials to evaluate the safety and effectiveness of photodynamic therapy using a newly-developed topical photosensitizing cream, aminolevulinic acid (ALA), for the treatment of various types of skin cancer and actinic keratosis, a precancerous condition.
A surprising number of variations exist in the way physicians diagnose and treat mammogram-detected breast cancer, according to a study. Researchers from Roswell Park Cancer Institute (RPCI) and Independent Health examined claims data to determine if practice volume impacted breast cancer outcomes.
Conjugated linoleic acid (CLA) decreases blood vessel formation --slowing tumor growth -- according to the results of a Roswell Park Cancer Institute study.
New, more effective follow-up treatments are needed to manage patients after surgery for pancreatic cancer because only a small percentage of these patients benefit from the current "standard" adjuvant therapy -- chemoradiation.
Roswell Park Cancer Institute announced this week that the FDA has approved PHOTOFRIN photodynamic therapy in the treatment of high-grade dysplasia associated with Barrett's esophagus.
African-American men are known to be at greater risk for developing and dying from prostate cancer. Racial differences in the androgenic stimulation of the prostate could be the reason prostate cancer occurs at a younger age and progresses more rapidly in African than Caucasian Americans.
Since January 2003, 36 faculty members of Roswell Park Cancer Institute (RPCI) have competed successfully for 43 grants which have a total value of $40.9 million and a first year value of $11.2 million. These grants include two prestigious program project grants awarded by the National Cancer Institute.
A new study suggests that surgeons are routinely performing an investigational procedure called sentinel node biopsy on women with early-stage breast cancer, which, the investigators say, may be affecting the generalizability of ongoing trials of the procedure.
Roswell Park Cancer Institute (RPCI) will host the 7th annual meeting of the Regional Cancer Center Consortium for the Biological Therapy of Cancer, February 26-28, in the Research Studies Center, RPCI, Elm & Carlton Streets, Buffalo, NY.
Results of a study support taking a revised view of prostate cancer and how best to treat it. Almost all advanced prostate cancer responds well at first to androgen deprivation therapy but the cancer recurs with a poor prognosis. This study suggests that these cases might need to be managed in a different way.
An oral vaccine administered in genetically engineered potatoes shows promise against the Hepatitis B Virus (HBV). The vaccine, which consists of only one protein from the virus, may be safer than other oral vaccines that use weakened living viruses.
This release offers an overview of skin cancer, how it develops and methods to treat it, including a non-surgical alternative called Photodynamic Therapy.
The Gilda Radner Familial Ovarian Cancer Registry, established in 1981 to track families who have included at least two first degree relatives diagnosed with ovarian cancer, is celebrating its 25th anniversary.
Scientists from the Department of Medicine, Roswell Park Cancer Institute, presented preliminary laboratory and clinical results of new therapies for hematologic cancers earlier this month at the 47th Annual Meeting of the American Society of Hematology, Atlanta, GA.
Susan McCann, PhD, will discuss the findings of her research in an oral presentation, "Dietary Lignan Intakes and Risk of Breast Cancer by Tumor Estrogen Receptor Status," at the 2006 annual meeting of the American Association for Cancer Research (AACR), Washington, DC.
Changing the size and surface charge of nanodevices significantly alters the way the nanodevices are taken up by organs and tissues in the body. This should allow for better targeting of treatments, according to scientists from the laboratory of Mohamed Khan, MD, PhD, and Lajos Balogh, PhD.
A diet with higher intakes of milk and tea may lower women's risk of developing acute myeloid leukemia (AML), according to scientists from the laboratory of Susan McCann, PhD, Division of Cancer Prevention & Population Sciences, Roswell Park Cancer Institute.
A new drug may boost the effectiveness of a widely used treatment for patients with non-Hodgkin lymphoma (NHL), while simultaneously overcoming drug resistance in those patients. That conclusion is based on a study conducted by scientists from the laboratory of Myron Czuczman, MD, Department of Medicine, Roswell Park Cancer Institute.