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Stem Cells

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Science

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Bioethics, Organoids, Human Embryonic Stem Cells, Animal Testing, Tissue Engineering, Regenerative Medicine

Scientists Initiate First Ethical Guidelines for Organs Cultivated in Vitro

In the latest edition of the journal “Science”, Jürgen Knoblich, a leading authority on stem cells and deputy director of the IMBA (Institute for Molecular Biotechnology of the Austrian Academy of Sciences), together with international experts, presents a first ethical guideline for research into human organ models. In the article, he also argues for critical and responsible engagement with the new technology.

Medicine

Science

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Biology, Cancer, Protein, Lipid, Fat, Stem Cells, Molecular Biology, Chemistry, waxes, triacylglycerols, Aging, Senescent

As Cells Age, the Fat Content Within Them Shifts

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As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids. By providing broad insights into the connection between lipids and cellular aging, the findings open the door for additional research that could one day support the development of lipid-based approaches to preventing cell death or hastening it in cancerous tumors.

Science

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super-resolution microscopy, stem cell differentiation

Super-Resolution Imaging Offers Fast Way to Discern Fate of Stem Cells

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Scientists funded by the National Institutes of Health have developed a new way to identify the state and fate of individual stem cells earlier than previously possible.

Medicine

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"Mysterious" Non-Protein-Coding RNAs Play Important Roles in Gene Expression, NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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Miami Doctors Publish Study of First Locally-Acquired Zika Transmission, Despite Low Profile, Zika Remains a High Concern, T Cells Join the Fight Against Zika, and More in the Zika Virus News Source

Get the latest on Zika in the Zika Virus News Source

Medicine

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Graft-versus-host disease

Moffitt Cancer Center Researchers Develop Novel Treatment to Prevent Graft-Versus-Host-Disease

TAMPA, Fla. – Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.  In a new study published as the cover story in Science Translational Medicine, Moffitt Cancer Center researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.

Medicine

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In Vitro Gametogenesis, IVG, Reproductive Technology, Experimental Reproductive Technology, Infertility Treatments, Infertility, Embryonic Stem Cell, IVG Legality, Experimental Technique, Experimental, Embryo, IVG Therapy, gene modification, Reproductive Legality

The Promise and Peril of Emerging Reproductive Technologies

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In-vitro gametogenesis is an experimental technique that allows scientists to grow embryos in a lab by reprograming adult cells to become sperm and egg cells.

Medicine

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C Diff, Stem Cell Transplant, Cancer, Antibiotic, Antibiotic Stewardship , Antibiotic Resistance

Walking the Tightrope

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Antibiotic use represents a special challenge, in which too much of a good thing can be dangerous to public health as a whole. The fight against a common, costly, hospital-acquired infection known as Clostridium difficile, or C. diff offers an illuminating case study in the area of so-called antibiotic stewardship.

Medicine

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Pancreas Cancer, Pancreas, Pancreatic Cancer, Pancreatic Surgery, pancreatic cancer research, Pancreatic Cancer Surgery, pancreatic cancer therapies, Pancreatic Cancer Action Network , Pancreatic cancer stem cells, Translational Cancer Research, Translational bioinformatics, Cancer Biomarkers, Pancreatic cancer biomarkers, cancer neoplasms, pancreatic c

World Renowned Surgeon and Researcher to Lead New Pancreatic Cancer Center at NYU Langone

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NYU Langone Medical Center has announced that internationally recognized surgeon and scientist Diane M. Simeone, MD, will join its Perlmutter Cancer Center on March 1 to serve as associate director for translational research and to lead its newly established pancreatic cancer center.

Medicine

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stem cell clinical trials , Stem Cells, Stem Cell Therapy, Rotator Cuff, rotator cuff repair, Rotator Cuff Tears, Adipose stem cells, FDA Approval, FDA approved

Stem Cell Therapy Trial at Sanford First of Its Kind in U.S. For Shoulder Injuries

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The first FDA-approved clinical trial of its kind in the United States using a person’s own fat-derived adult stem cells to treat shoulder injuries is available at Sanford Health.

Science

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Lymphoma, Affimed, Natural Killer Cells, Cord Blood, Stem Cell

MD Anderson and Affimed Announce Clinical Immuno-Oncology Development Collaboration

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The University of Texas MD Anderson Cancer Center and Affimed N.V., a clinical stage biopharmaceutical company focused on discovering and developing highly targeted cancer immunotherapies, today announced an exclusive strategic clinical development and commercialization collaboration to evaluate Affimed’s TandAb technology in combination with MD Anderson’s natural killer cell (NK) product.

Medicine

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Cardiac, Stem Cell, Synthetic

Synthetic Stem Cells Could Offer Therapeutic Benefits, Reduced Risks

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Researchers have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies.

Medicine

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Embryonic Stem Cells, Stem Cells, Cardiomyocytes, Pacemaker Cells, Pacemaker, Israel, Biological Pacemaker, Cardiovascular

Canadian-Israeli Development: A New Biological Pacemaker

Using human embryonic stem cells to create a type of cardiac cells known as sinotrial (SA) node pacemaker cells, researchers have developed a biological pacemaker that overcomes many of the limitations of electrical pacemakers.

Medicine

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stem cell clinical trials , Pediatric Heart Surgery, Hypoplastic Left Heart Syndrome

First U.S. Babies Treated in Unique Study of Adult Stem Cell Therapy for Congenital Heart Disease

Researchers at the University of Maryland School of Medicine (UM SOM) and the Interdisciplinary Stem Cell Institute (ISCI) at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

Science

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Tissue Regeneration, Muscles, Nanomaterials, Material Science, Stem Cell, Tissue Repair, Biomaterials

UW Researcher Pursues Synthetic 'Scaffolds' for Muscle Regeneration

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Miqin Zhang, a professor of materials science and engineering at the University of Washington, is looking for ways to help the body heal itself when injury, disease or surgery cause large-scale damage to one type of tissue in particular: skeletal muscle.

Medicine

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Joint Replacement Surgery

Keck School of Medicine Receives $2.5 Million from California Institute for Regenerative Medicine (CIRM) for Translational Osteoarthritis Research

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Denis Evseenko, MD, PhD, of Keck Medicine of USC receives a $2.5 million grant from CIRM to develop an off-the-shelf therapy for osteoarthritis. Osteoarthritis affects tens of millions of Americans, with that number expected to grow exponentially due to obesity and longer lifespans.

Science

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Tooth regeneration, Stem Cells, Hydrogel, Tissue Engineering

New Stem Cell Delivery Approach Regenerates Dental Pulp-Like Tissue in a Rodent Model

Delivery of stem cells to damaged tooth roots using a collagen-derived biomaterial is effective at regenerating dental pulp-like tissue and shows promise as a potential therapy for restoring natural tooth function in a rodent model.

Medicine

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Stem Cell ‘Living Bandage’ for Knee Injuries Trialled in Humans

A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.

Medicine

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Glioma, glioblastoma multiforme (GBM, Neuroscience, Neurosurgery, FOXD1, ALDH1A3, Glioma stem cells

Attractive Drug Candidate Identified to Target Glioma Brain Tumors

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In a Cancer Research paper, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

Medicine

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Zambidis, Kimmel Cancer Center, Embryonic Stem Cells, ESCs

Researchers Turn Back the Clock on Human Embryonic Stem Cells

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Johns Hopkins scientists report success in using a cocktail of cell-signaling chemicals to further wind back the biological clock of human embryonic stem cells (ESCs), giving the cells the same flexibility researchers have prized in mice ESCs.







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