Using high-tech human heart models and mouse experiments, scientists at Johns Hopkins and Germany’s University of Bonn have shown that beams of light could replace electric shocks in patients reeling from a deadly heart rhythm disorder.
University of Utah researchers have found that the structure of an insulin molecule produced by predatory cone snails may be an improvement over current fast-acting therapeutic insulin.
In research published in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles’ heel shared by all known types of Ebola virus. Two antibodies developed with this strategy blocked the invasion of human cells by all five ebolaviruses. The team included scientists from Albert Einstein College of Medicine, U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Integrated Biotherapeutics, Vanderbilt University Medical Center, and The Scripps Research Institute.
In an important breakthrough for the forensic science community, researchers have developed the first-ever biological identification method that exploits the information encoded in proteins of human hair.
A world leader in pediatric genomics from The Children’s Hospital of Philadelphia (CHOP) will address a major conference in precision medicine this month, as research and business experts exchange state-of-the-art progress in applying DNA discovery technology to advancing human health. Dr. Hakon Hakonarson will address the inaugural 2016 Advances in Genome Biology (AGBT) Precision Health Meeting on Sept. 22 in Scottsdale, Ariz.
The Exascale Computing Project today announced its first round of funding with the selection of application development proposals, including three Argonne-led projects.
They are the tiny motors present in many of the human body’s most complex systems. Cilia are hair-like structures that oscillate in waves, and are present in the brain, kidneys, lungs and reproductive system. They move liquids such as cerebrospinal fluid and mucus past the cell surface, and throughout the body. Flagella are whip-like structures that steer cells along.
New York University biologist Elodie Ghedin will study the host response to Zika virus infections under a $1 million grant from the National Institute of Allergy and Infectious Diseases.
Scientists from the University of Southampton have reengineered the fundamental process of photosynthesis to power useful chemical reactions that could be used to produce biofuels, pharmaceuticals and fine chemicals.
Columbia University will award the 2016 Louisa Gross Horwitz Prize to Howard Cedar, PhD, and Aharon Razin, PhD, of the Hebrew University of Jerusalem, and Gary Felsenfeld, PhD, of the National Institutes of Health.
A recent study reveals different fungal species secrete a rich set of enzymes that share similar functions, despite species-specific differences in the amino acid sequences of these enzymes.
In herbivores' guts, fungi digest plant material. Researchers characterized several fungi involved in this digestion process and identified a large number of enzymes that work synergistically to degrade the raw biomass.
Hard labor might be the very thing we try to avoid on Labor Day. But our cells and their components don’t have the luxury of taking a day off. We at NIH's National Institute of General Medical Sciences give a shout out to some of these tireless cellular workers.
A paper published in ACS Nano, one of the top nanotechnology journals in the world, explores this topic. “Modeling and Analysis of Intercalant Effects on Circular DNA Conformation” focuses on the effect of the intercalating agent ethidium bromide (a mimic for many chemotherapy drugs) on the tertiary structure of DNA.
A collaboration of Chinese and U.S. chemists has laid out a highly efficient new method to convert abundant organic molecules into new medicines. Teams led by the Shanghai Institute of Organic Chemistry (SIOC) and the University of Wisconsin-Madison describe a way to convert carbon-hydrogen bonds into nitriles, common components of bioactive molecules used in medicinal and agricultural applications.
Using a new, lightning-fast camera paired with an electron microscope, University of Maryland School of Medicine scientists have captured images of one of the smallest human proteins to be “seen” with a microscope.
Using sign language with intensive speech therapy may be an effective treatment for children with a rare speech disorder called apraxia of speech, according to Penn State College of Medicine researchers.
Scientists discovered that the major developmental function of heterochromatin – a form of tight DNA packaging found in chromosomes – is likely the suppression of virus-like DNA elements known as transposons, which can copy and paste themselves throughout the genome, potentially causing diseases.
Sandia and UNM researchers developed a bio-inspired bubble-like membrane to capture CO2 from coal-fired power plants efficiently. The CO2 Memzyme could capture CO2 equivalent to planting 63 million trees and letting them grow for 10 years from just one power plant.
Scientists invent a multi-view microscope that doubles the resolution of images without exposing them to an increased amount of light or prolonging the imaging process.
Dr. Joaquín Madrenas Brings Decades of Research Experience to the Institute
Roger Tsien, PhD, co-winner of the 2008 Nobel Prize in chemistry and professor of pharmacology, chemistry and biochemistry at University of California San Diego School of Medicine for 27 years, died August 24 in Eugene, Ore. He was 64.
Sanford Burnham Prebys Medical Discovery Institute (SBP), the Johns Hopkins University School of Medicine, the Salk Institute for Biological Studies, and the University of Michigan will embark on a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced.
In a study of children with brain shunts at Children’s of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current “gold standard” test for detecting bacterial infections in the shunts.
A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment. With further development, this biomaterial could be used to control when immature stem cells differentiate into more specialized cells for regenerative and tissue-engineering-based therapies.
Functional human collagen has been impossible to create in the lab. Now, a team of University of Wisconsin—Madison researchers describe what may be the key to growing functional, natural collagen fibers outside of the body: symmetry.
Here is a list of the ASBMB's annual award winners.
A new study from University of Michigan researchers challenges the widely held assumption that biofuels such as ethanol and biodiesel are inherently carbon neutral.
The Global Biological Standards Institute (GBSI) targets the quality of research antibodies at a workshop at Asilomar next month in its ongoing efforts to improve reproducibility in preclinical research. Antibody Validation: Standards, Policies, and Practices brings together 100 leaders representing academia, antibody producers, pharma, funders, journals and policy makers to share perspectives, build consensus and recommend actionable solutions for improving accuracy in research antibody usage and validation. It is the first convening of all such stakeholder groups with the express purpose of developing antibody standards.
People with high levels of four biomarkers in the blood may be more likely to develop a stroke than people with low levels of the biomarkers, according to a study published in the August 24, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Two Wichita State University professors are conducting research on an invasive plant species to assist Kansas ranchers in their practices.
The U.S. Department of Energy announced last week that 43 small businesses will participate in the second round of the Small Business Vouchers (SBV) pilot.
In a nation-wide competition, six teams of undergraduate engineering students produced prize-winning designs for technological advances to improve human health. The Design by Biomedical Undergraduate Teams (DEBUT) Challenge winning teams designed tools for a myriad of health care challenges, including diagnosing tuberculosis (TB) in children and a safer alternative for central venous catheter placements.
In a collaboration between Rensselaer Polytechnic Institute and the Icahn School of Medicine at Mount Sinai, researchers are exploring the link between diet, obesity-linked Type 2 diabetes, and intervertebral disc degeneration.
Muyinatu A. Lediju Bell, a Johns Hopkins engineering faculty member who designs medical imaging systems that link light, sound and robotics to produce clearer pictures, was honored today by MIT Technology Review, which placed her on its 2016 list of 35 Innovators Under 35. The list annually spotlights the nation’s most promising young scientists.
A novel MRI method that detects low levels of zinc ion can help distinguish healthy prostate tissue from cancer, UT Southwestern Medical Center radiologists have determined.
To solve complex global challenges, like the social and environmental impacts of bioenergy development, researchers turn to PIRE. That stands for Partnership in International Research and Education and is a program through the National Science Foundation.
Permanent brain damage from a stroke may be reversible thanks to a developing therapeutic technique. The novel approach combines transplanted human stem cells with a special protein that the U.S. Food and Drug Administration already approved for clinical studies in new stroke patients.
Scientists from the Mechanobiology Institute at the National University of Singapore have discovered a new mechanism of cell boundary elongation. Elongation and contraction of the cell boundary is essential for directing changes in cell shape, which is required for the correct development of tissues and organs.
As coastal ecosystems feel the heat of climate change worldwide, new research shows the humble mussel and marsh grass form an intimate interaction known as mutualism that benefits both partner species and may be critical to helping these ecosystems bounce back from extreme climatic events such as drought.
Kim O’Connor, a professor in Tulane University’s Department of Chemical and Biomolecular Engineering, received a three-year $599,638 grant from the National Science Foundation to study ways to improve the survival of mesenchymal stem cells once they are implanted in patients.
The New York Academy of Medicine is proud to announce the recipients of its prestigious annual awards for distinguished contributions by individuals in health policy, public health, clinical practice, biomedical research and an individual who has made significant contributions to the Academy.
Researchers are on a real-life search for what one calls “the ultimate Pokémon”: Zenkerella, an elusive scaly-tailed squirrel that has never been spotted alive by scientists. However, biologists recently found three newly dead specimens that hint at how the “living fossil” has evolved over the past 49 million years.
A new technology creates images resolved enough to enable consistent diagnoses across populations for the first time.
Graphene nanoribbons (GNRs) bend and twist easily in solution, making them adaptable for biological uses like DNA analysis, drug delivery and biomimetic applications, according to scientists at Rice University.
So far industry has only harnessed a fraction of the yeast diversity available for biotechnological applications, including biofuel production. In the Proceedings of the National Academy of Sciences, a team led by DOE Joint Genome Institute researchers aims to help boost the use of a wider range of yeasts.
Scientists at The Scripps Research Institute have created a ribozyme that can basically serve both to amplify genetic information and generate functional molecules, a big step toward the laboratory re-creation of the “RNA world,” generally believed to have preceded modern life forms based on DNA and proteins.
Using a unique single-molecule force measurement tool, a research team has developed a clearer understanding of how platelets sense the mechanical forces they encounter during bleeding to initiate the cascading process that leads to blood clotting.
It isn’t often that a graduate student makes a spectacular technical leap in his field, or invents a process that can have a significant impact on a real-world problem. Di Liu did both.
A Kansas State University-led international team of 114 researchers has sequenced the genome of the tobacco hornworm, or Manduca sexta.
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