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Genetic Diversity Within Tumors Predicts Outcome in Head and Neck Cancer

A new measure of the heterogeneity – the variety of genetic mutations – of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer.

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Geisinger Partners with Indivumed for Personalized Medicine Initiative

Geisinger Health System announced plans to partner with Indivumed, a leading provider of services enabling individualized cancer therapy.

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New Diagnostic Technology May Lead to Individualized Treatments for Prostate Cancer

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A research team jointly led by scientists from Cedars-Sinai Medical Center and the University of California, Los Angeles, have enhanced a device they developed to identify and “grab” circulating tumor cells, or CTCs, that break away from cancers and enter the blood, often leading to the spread of cancer to other parts of the body. If more studies confirm the technology’s effectiveness, the NanoVelcro Chip device could enable doctors to access and identify cancerous cells in the bloodstream, which would provide the diagnostic information needed to create individually tailored treatments for patients with prostate cancer.

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New Multiple Myeloma Treatment Guidelines Personalize Therapy for Patients

Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy. The guidelines are published in the current issue of the journal Mayo Clinic Proceedings and represent a consensus opinion of hematologists at Mayo Clinic Cancer Center sites in Minnesota, Florida and Arizona.

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Personal Monitor System Could Change Healthcare

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A wireless personal health monitoring system using smartphones to upload data via the Internet will revolutionize the U.S. healthcare industry, its pioneering creators say.

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Gene Profile May Help Identify Risk for Hormone-Sensitive, Hormone-Insensitive Breast Cancer

• Levels of 13 genes elevated in unaffected breasts of women with hormone receptor-negative breast cancer. • Eight of the genes were associated with lipid metabolism. • Ability to identify those at risk may help tailor prevention strategies.

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Transplanted Brain Cells in Monkeys Light Up Personalized Therapy

For the first time, scientists have transplanted neural cells derived from a monkey's skin into its brain and watched the cells develop into several types of mature brain cells, according to the authors of a new study in Cell Reports. After six months, the cells looked entirely normal, and were only detectable because they initially were tagged with a fluorescent protein.

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Genomic Screening to Detect Preventable Rare Diseases in Healthy People

Millions of people unknowingly carry rare gene mutations that put them at high risk of developing preventable diseases such as colorectal cancer, breast cancer, and several catastrophic blood vessel disorders. University of North Carolina experts from the School of Medicine and from the Gillings School of Global Public Health propose that screening healthy adults for these and other specific, rare genetic disorders could potentially prevent these diseases.

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Genomic Analysis Study at the Cancer Institute of New Jersey Seeks Paths to Personalized Treatment

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Investigators working on the precision medicine initiative at The Cancer Institute of New Jersey are embarking on a genomic analysis study which could illuminate more options in developing personalized and precise treatments for cancer patients. It is believed that some rare and poor prognosis cancers that currently have limited treatment options may harbor genomic changes that can potentially be treated with specific targeted therapies. Through Next Generation Sequencing and data analysis of DNA in tissue samples, researchers aim to identify these changes in order to guide treatment.

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Student Innovator at Rensselaer Polytechnic Institute Aims To Personalize Medicine With Implantable Sensors

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Rebecca Wachs has invented a new implantable sensor with the ability to wirelessly transmit data from the site of a knee replacement, spinal fusion, or other orthopedic surgery. Simple, robust, and inexpensive to make, her sensor holds the promise of advancing personalized medicine by giving doctors an unprecedented wealth of information about how an individual patient is healing.

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