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Medicine

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Alzheimer's, Mild Cognitive Impairment, Genetic Test, Pharmacogenetics

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Alzheimer’s Drug Prescribed ‘Off-Label’ for Mild Cognitive Impairment Could Pose Risk for Some

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Donepezil, a medication that is approved to treat people with Alzheimer’s disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

Medicine

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antibiotic resisistance, Pediatric Infectious Disease, Enterobacteriaceae, antibiotic usage, Antibiotics, Pediatrics

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Antibiotic Resistance: A Burgeoning Problem for Kids Too

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In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.

Medicine

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Shorter Radiation Use, BRCA Gene News, Staging Endometrial Cancer, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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Amyloid, Amyloid Fibrils, Fibrils, Staphylococcus Aureus, Staphylococcus Aureus (Mrsa), Staphylococcus, MRSA, antibiotic resisistance, Antibiotics

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Novel Amyloid Structure Could Lead to New Types of Antibiotics

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Researchers have discovered unique amyloid fibers used by the highly drug resistant Staphylococcus aureus bacterium (which causes MRSA). The findings could lead to new types of antibiotics with a novel mechanism of action for attacking bacterial toxins.

Medicine

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 1-Mar-2017 4:00 PM EST

Medicine

Science

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Science Exchange Online Marketplace Now Offers Eurofins Services for Drug Development

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/PRNewswire/ -- Science Exchange and Eurofins are excited to announce that Eurofins Central Laboratory is now a service provider listed on the Science Exchange marketplace for outsourced research services. This means that pharmaceutical and biotech companies around the world now have faster access to Eurofins's Clinical Testing portfolio, as well as its end-to-end analytical testing solutions from Drug Discovery to Product Testing.

Medicine

Science

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Melanoma, Aging, adjuvant therapy

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Anti-Aging Gene Identified as a Novel Promising Therapeutic Target for Older Melanoma Patients

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Wistar scientists have shown an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease.

Medicine

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Precision Medicine, personalized medicine, White House Precision Medicine intitiative, genome medicine, Personalized Therapies, Undiagnosed Diseases

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White House Strategist to Lead UAB’s Personalized Medicine Institute

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Matthew Might, Ph.D., a renowned computer scientist and strategic leader appointed to the White House Precision Medicine Initiative by former President Barack Obama, has been named the inaugural director of the Hugh Kaul Personalized Medicine Institute at UAB.

Medicine

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Pneumonia, Influenza, viral pneumonia, Viruses, Disease Prevention, Asthma, Allergies, Drugs, asthma drugs, Accolate, Singulair, repurposing drugs, University Of Virginia, University of Virginia School of Medicine, UVA, UVA School of Medicine, Carter Immunology Center, Beirne B. Carter, Virology, Geriatrics, Infectious Diseases, Thomas J. Braciale, Amber Cardan

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Asthma Drugs Could Prevent Deadly Form of Pneumonia, Research Suggests

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Two drugs used to treat asthma and allergies may offer a way to prevent a form of pneumonia that can kill up to 40 percent of people who contract it, researchers at the University of Virginia School of Medicine have found.

Medicine

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ASHP Releases AHFS Drug Information, 2017 Edition

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Trusted, Evidence-based Resource Helps Practitioners Make Informed Drug Therapy Decisions

Medicine

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Popular Heartburn Drugs Linked to Gradual Yet ‘Silent’ Kidney Damage

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Taking popular heartburn medication for prolonged periods may lead to serious kidney damage, even in people who show no signs of kidney problems, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System. The drugs are sold under brand names such as Prevacid, Prilosec, Nexium and Protonix.

Medicine

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TSRI-Invented Compound Ozanimod Shows Positive Results in Late-Stage Clinical Trial for Relapsing Multiple Sclerosis

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Results from a new Phase 3 study conducted by the Celgene Corporation demonstrate that ozanimod, a drug candidate originally discovered and optimized at The Scripps Research Institute (TSRI), can reduce the frequency of multiple sclerosis relapse.

Medicine

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Drugs That Alter Inhibitory Targets Offer Therapeutic Strategies for Autism, Schizophrenia

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Researchers at SUNY Downstate recently discovered that an inhibitory brain receptor triggers synaptic pruning in adolescence. Drugs that selectively target these receptors, when administered during adolescence, can alter synapse number, with possible implications for the treatment of autism and schizophrenia.

Medicine

Channels:

Medication Adherence, medication research, Medication, Congestive Heart Failure, cardiovascuar disease

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Interventions Improve Medication Adherence, Decrease Risk of Hospitalizations

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Poor adherence to medication regimens is a common problem among patients with cardiovascular diseases like high blood pressure, heart disease, and heart failure. Poor adherence is one reason mortality rates among those patients remain high. Todd Ruppar, associate professor in the Sinclair School of Nursing at the University of Missouri, has found that a variety of interventions aimed at increasing medication adherence can help people with cardiovascular disease avoid the hospital. Ruppar will address the barriers to medication adherence during the Public Health Grand Rounds offered by the Centers for Disease Control and Prevention (CDC) on Tuesday, Feb. 21 in Atlanta.

Medicine

Science

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An Alternative to Opioids? Compound From Marine Snail Is Potent Pain Reliever

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A tiny snail may offer an alternative to opioids for pain relief. Scientists at the University of Utah have found a compound that blocks pain by targeting a pathway not associated with opioids. Research in rodents indicates that the benefits continue long after the compound have cleared the body.

Science

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Biological and Environmental Research, biological and environmental sciences, Advanced Scientific Computing Research, Nature, Nature (magazine), Peptides, Proteins, Protein, protein analysis, Drug Design, drug, Drugs, hyperstable constrained peptides, Peptide, peptide drugs, Computational Methods, custom drugs, Seattle Structural Genomics Center for Infect

Unlocking Peptide Potential

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Powerful new computational methods now enable scientists to design a virtually unlimited variety of hyperstable peptide structures not found in nature. This research opens a new frontier in drug discovery.

Medicine

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Micro-RNA May Amplify Effectiveness of Sorafenib in Difficult Liver Cancer Cases

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Only 25% of patients respond to sorafenib treatment, so researchers have endeavored to understand its mechanism of action and discover a way to boost its effectiveness.

Science

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Placenta, Autism, UC Davis MIND Institute, DLL1, Methylation, epigentics

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Placenta Provides Time Capsule for Autism Studies

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In two recent studies, researchers at UC Davis have shown that placental tissue can provide critical information about the epigenetic landscape that influences fetal development.

Medicine

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Experimental Biology 2017, Faseb, Anatomy, Physiological, Biochemistry, Molecular Biology, Pathology, Nutrition, Pharmacology

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Speakers Announced for 2017 Experimental Biology Meeting

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World-renowned scientists will present pioneering research and discuss key issues affecting the life sciences at the 2017 Experimental Biology meeting (EB 2017), the premier annual meeting of six scientific societies in Chicago to be held April 22–26.

Medicine

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Insomnia Medication, Insomnia Meds, Insomnia, Physician Education, Pharmacology, Prescribing Patterns, Clinical Decision Making, Treatment Choices, Habits, Decision Influences

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Mental Shortcuts

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Clinical decision-making and treatment choice is a complex cognitive process influenced by multiple variables.







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