When it comes to preventing blood clots after a knee replacement, good old aspirin may be just as effective as newer, more expensive drugs, such as rivaroxaban (Xarelto), according to a study by University of Michigan orthopedic surgeons.
New research at the 2018 ACR/ARHP Annual Meeting builds on current evidence that hematopoietic stem cell transplantation can significantly improve long-term outcomes for patients with severe scleroderma when compared to use of conventional treatment with cyclophosphamide.
The 2018 American College of Rheumatology/American Rheumatology Health Professionals Annual Meeting.
Data on the molecular makeup and drug sensitivity of hundreds of patient samples could accelerate progress against the aggressive blood cancer acute myeloid leukemia.
Women who experience high blood pressure prior to labor may be more likely to deliver babies with a lower Apgar score, a measure of a newborn’s physical health, suggests new research presented at the ANESTHESIOLOGY® 2018 annual meeting.
Johns Hopkins students will be presenting posters of their engineering projects designed to fill needs in clinical care
Mayo Clinic的研究人员已经确定了三种特定的基因类型，这些基因类型会使非洲裔美国人的骨髓瘤（myeloma）诊断增加两到三倍。 研究人员还展示了DNA分析在更准确地研究种族和种族混合上的效果。 该研究结果发表在《血癌学杂志》（Blood Cancer Journal）上。
Pesquisadores da Mayo Clinic identificaram três tipos de genes específicos que explicam um aumento conhecido de duas a três vezes no diagnóstico de mieloma entre afro-americanos. Os pesquisadores também demonstraram a capacidade de estudar raça e mistura racial com mais precisão usando análise de DNA. As descobertas foram publicadas no periódico Blood Cancer Journal.
Los científicos de Mayo Clinic identificaron tres tipos específicos de genes a los que se atribuye el aumento al triple de los diagnósticos de mieloma entre los afroamericanos. Los científicos también demostraron que se puede estudiar la raza y el mestizaje con el análisis del ADN.
Ronald Paquette, MD, clinical director of the Cedars-Sinai Blood & Marrow Transplant Program at the Samuel Oschin Comprehensive Cancer Institute, recently was accepted as a member of the Myeloproliferative Neoplasm Research Consortium. The group is funded by the National Cancer Institute.
• Certain parameters measured by ultrasound helped predict the success of an arteriovenous fistula, the preferred type of hemodialysis vascular access, in individual patients.
BOSTON – (October 10, 2018) – Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins. Scientists at Joslin Diabetes Center now have shown that one amino acid, alanine, may produce a short-term lowering of glucose levels by altering energy metabolism in the cell.
Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. However, scientists know little about the early stages of the condition. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC Santa Barbara have discovered that host responses during sepsis progression can vary in important ways based on pathogen type—which could lead to more effective treatments. The study published today in Cell Host and Microbe.
A UPMC-developed test for diagnosis of thyroid nodules, ThyroSeq® Genomic Classifier, has been approved for coverage by its Medicare Administrative Contractor, Novitas Solutions. This decision paves the way for the test to be accessible to more than 50 million Medicare patients nationwide.
ROCHESTER Minn. — Researchers at Mayo Clinic have identified three specific gene types that account for a known two-to-three-fold increase in myeloma diagnoses among African-Americans. Researchers also demonstrated the ability to study race and racial admixture more accurately using DNA analysis. The findings were published today in Blood Cancer Journal.
Using a statistical technique called network meta-analysis, researchers have combined the results of dozens of studies of dietary oils to identify those with the best effect on patients' LDL cholesterol and other blood lipids.
Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease. This proof-of-concept finding in animals and stem cells may lay the foundation for better treatments for children with the rare, frequently fatal disease.
Lifestyle intervention delivered in churches by community-based health workers led to a significant reduction in blood pressure among African Americans compared to health education alone, according to a study led by researchers at NYU School of Medicine publishing online October 9 in the journal Circulation: Cardiovascular Quality and Outcomes.
The phase II study was led by researchers at The University of Texas MD Anderson Cancer Center. Results of the study, the first randomized neoadjuvant clinical trial of immune checkpoint blockade for melanoma patients, are reported in Nature Medicine.
The European Association for the Study of Diabetes (EASD) and the American Diabetes Association (ADA) have produced an updated consensus statement on how to manage hyperglycaemia (high blood sugar) in patients with type 2 diabetes.
The University of Texas MD Anderson Cancer Center and Cyclacel Pharmaceuticals, Inc., today announced a three-year strategic alliance agreement that will enable clinical evaluation for safety and efficacy of three Cyclacel medicines in patients with hematological malignancies, including chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and other advanced leukemias.
A study led by a UAB oncologist finds that adolescents and young adults with a form of leukemia are disposed to higher relapse rates.
Los investigadores de Mayo Clinic crearon un recurso genético para pronóstico del síndrome mielodisplásico (SMD). Los resultados se publican en la edición impresa correspondiente al mes de octubre de Mayo Clinic Proceedings.
Clinical trial to test potential for blood-based biopsies to identify cancer patients more likely to response to treatment with immunotherapy
روتشستر، مينيسوتا – طوّر الباحثون لدى Mayo Clinic أداة تكهنية جديدة تعتمد على الجينات للتكهن بمتلازمات خلل التنسج النقوي (MDS). ومن المقرر أن تنشر نتائج اكتشافهم في عدد أكتوبر المطبوع من مجلة أحداث Mayo Clinic.
Mayo Clinic的研究人员开发了一种新的基于遗传学的骨髓增生异常综合征（myelodysplastic syndrome，MDS）预后工具。 他们的研究结果发表在10月份的Mayo Clinic Proceedings杂志的印刷版上。
Pesquisadores da Mayo Clinic desenvolveram uma nova ferramenta de prognóstico com base em genética para a síndrome mielodisplástica (MDS). As descobertas da equipe foram publicadas na edição de outubro da Mayo Clinic Proceedings.
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. They caution in the journal Pediatric Blood & Cancer that expediting HLH treatment may miss underlying malignancies that could end up being fatal to the patient.
Researchers at Mayo Clinic have developed a new genetics-based prognostic tool for myelodysplastic syndrome. Their findings are published in the October print issue of Mayo Clinic Proceedings.
Results may lead to better management of complex eye condition
Loyola University Chicago and Loyola Medicine have announced plans to become the first Chicago center to produce cancer-fighting CAR-T cells to treat leukemia and lymphoma. Loyola plans to produce a more purified CAR-T cell that could reduce toxicities and costs.
UCI School of Medicine researchers have been awarded a $3.4 million grant by the National Cancer Institute (NCI) as part of the Beau Biden Cancer Moonshot initiative. The funding will support efforts to provide proof of principal data for an entirely new class of cancer killing immunotherapeutics with the potential to treat highly diverse types of cancer, from leukemia to breast cancer.
Chicago (Sep. 25, 2018): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded this year’s Dr. Patricia Greene Leadership Award to Kaye Schmidt, MA RN NEA-BC CPHON®. Schmidt was presented with this award at the 42nd Annual APHON Conference and Exhibit, held September 13-15, in Savannah, GA.
Chicago (Sep. 25, 2018) The Association of Pediatric Hematology/Oncology Nurses (APHON) announced the recipients of the 2018 APHON Membership Awards at its 42nd Annual Conference and Exhibit, held September 13-15 in Savannah, GA. APHON Membership Awards recognize members who have shown outstanding achievement in their field.
Chicago (Sep. 25, 2018): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded Marilyn J. Hockenberry, PhD RN PPCNP-BC FAAN with the 2018 Dr. Nancy E. Kline Mentoring Award. Hockenberry’s achievement was formally announced at the 42nd Annual APHON Conference and Exhibit, on September 14 in Savannah, GA.
Chicago (Sep. 25, 2018): The Association of Pediatric Hematology/Oncology Nurses (APHON) has presented Genevieve Foley, MSN RN with the 2018 Dr. Casey Hooke Distinguished Service Award. Foley’s achievement was officially announced at the 42nd APHON Annual Conference and Exhibit, held September 13-15 in Savannah, GA. This award is presented to an APHON member who has demonstrated excellence to service and to leadership of APHON.
Hackensack Meridian Health K. Hovnanian Children’s Hospital at Jersey Shore University Medical Center to host an event dedicated to pediatric cancer research and programs on September 28, from 4 p.m. to 8 p.m. Tackle Kids Cancer will take place at iPlay America in Freehold, NJ.
Two recent studies in the journal Leukemia present a new approach for bone marrow donation and transplant that preclinical laboratory tests suggest could make the life-saving procedure safer and more effective for patients. Researchers say their studies demonstrate that use of an experimental drug called CASIN in laboratory mice results in higher efficiency when harvesting blood stem cells from donors and less toxicity in transplant recipients.
A new auto-commentary looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can be used to improve drug development and personalized medicine.
Sickle cell disease is a common inherited blood disorder, affecting an estimated 100,000 Americans of different racial and ethnic groups. A Rutgers Cancer Institute of New Jersey expert shares more about the importance of early diagnosis and comprehensive management of this disease.
Mercy Medical Center now offers the VenaSeal™ procedure as a new option for treating venous reflux disease and varicose veins.
In proof-of-concept experiments, researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. Researchers deliver a therapeutic enzyme via the cellular equivalent of a Trojan Horse, using platelets to protect the key enzyme hidden inside.
Healthy red blood cells are round, but for those with sickle cell disease, the red blood cells become sticky and hard because of an abnormal amount of protein in the blood. The red blood cells form the shape of a sickle, or crescent.
Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor (ET). Currently, ET is treated using repurposed medications originally developed for high blood pressure or seizures.
In a new analysis of data submitted to Maryland’s state trauma registry from 2005 to 2017, Johns Hopkins Medicine researchers found that gunshot victims are approximately five times more likely to require blood transfusions, they require 10 times more blood units and are 14 times more likely to die than people seriously injured by motor vehicles, non-gun assaults, falls or stabs.
A three-year, $1.8 million grant from the National Institutes of Health will enable researchers at the University of Illinois at Chicago to develop portable, easy-to-use sensors that can detect toxic metals in a single drop of blood. The sensors would allow for faster and cheaper research, as well as rapid detection of metals including manganese and lead, both of which are powerful neurotoxins that can affect cognitive development and neuromotor function.
A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at Washington University School of Medicine in St. Louis. Such a practice could help doctors identify patients at high risk of disease recurrence early after a transplant and help guide treatment decisions.
A new $3 million, five-year grant from the National Heart, Lung and Blood Institute will allow researchers to determine whether a unique program designed to educate people with uncontrolled hypertension — also known as high blood pressure — about the importance of getting their blood pressure under control can help reduce the risk of developing chronic and expensive-to-treat secondary cardiovascular conditions among this high-risk group.
Omacetaxine (to block protein synthesis) with venetoclax (to block oxidative phosphorylation), was highly effective against CD123+ leukemia stem cells.
Researchers from St. Jude Children’s Research Hospital and the University of North Carolina Lineberger Comprehensive Cancer Center have made important discoveries that could lead to better treatment for a rare blood cancer in children that has features of both acute myeloid leukemia and acute lymphoblastic leukemia.
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