A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern’s Simmons Cancer Center announced.
A team of scientists from across the U.S. has found a new way to create molecular interconnections that can give a certain class of materials exciting new properties, including improving their ability to catalyze chemical reactions or harvest energy from light.
Nicotinomide riboside (NR) mimics caloric restriction, kick-starting the same pathways responsible for reducing cardiovascular aging.
People have become familiar with “bomb cyclones” this winter, as several powerful winter storms brought strong winds and heavy precipitation to the U.S. east coast, knocking out power and causing flooding. Scientists have extensively studied potential causes behind these year-to-year changes in attempt to better forecast storm tracks and their extreme impacts, but new research from scientists at the Stony Brook University School of Marine and Atmospheric Sciences, funded by NOAA Research’s MAPP Program, identifies another crucial controlling force.
Researchers at the University of Utah and Konkuk University found that news stories are perceived as biased based on who shares that story on social media, regardless if the actual story is biased.
Materials inspired by disappearing Hollywood dinosaurs and real-life shy squid have been invented by UCI engineers, according to new findings in Science this Friday.
Patients traveling to developing countries for plastic surgery procedures may experience severe complications—requiring extensive and costly treatment after they return to the United States, reports a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
One in 10 electronic dance music (EDM) party attendees have misused opioids in the past year, exceeding the national average, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing.
A multi-institutional team of scientists describes a new technique that can meld ions from up to eight different elements to form what are known as high entropy alloyed nanoparticles.
Biologists have discovered evidence for a new path of evolution, and with it a deeper understanding of how quickly organisms such as viruses can adapt to their environment. The findings, which address mysteries of how genes acquire new functions and how mutations arise, apply to investigations of viral diseases.
A drug that reverses the effects of a cellular stress response restores learning and memory in mice with concussions. Now researchers can see the atomic-scale details of how the drug interacts with its protein target.
Breast augmentation with implants does not interfere with the ability to detect later breast cancers—in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Researchers from UT Southwestern’s Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Internal Medicine’s Division of Nephrology recently published work in Nature that reveals the molecular structure of the so-called “anti-aging” protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic processes.
Researchers at the University of Georgia have discovered that dormancy of the parasite Trypanosoma cruzi prevents effective drug treatment for Chagas disease, which kills more than 50,000 people each year in Central and South America and is a growing threat in the United States and Europe.
If you're like most Americans, you see tax season as stressful - especially as the April 15 deadline looms. But, you're not alone. About 85 percent of taxpayers overstate their actual federal income taxes, according to new research from Michigan State University.
Making the transition from high school to college may be stressful — but it can be downright depressing for students who graduate from a school with peers of high academic ability and wind up at a college with students of lesser ability, according to a new study.
Very slow brain waves, long considered an artifact of brain scanning techniques, may be more important than anyone had realized. Researchers at Washington University School of Medicine in St. Louis have found that very slow waves are directly linked to state of consciousness and may be involved in coordinating activity across distant brain regions.
More than half of U.S. physicians say they experience burnout in their work. Today, Mayo Clinic and other leading medical centers have published a “Charter on Physician Well-Being” as an intended model for medical organizations to not only minimize and manage physician burnout, but also promote physician well-being. The charter, which has been endorsed or supported by many major medical organizations, including the American Medical Association and the American Association of Medical Colleges, appears online in JAMA.
An estimated 2 million people in the U.S. are addicted to prescription opioids—powerful doctor-prescribed medications for chronic or severe pain. The drugs are commonly prescribed to treat gastrointestinal pain caused by conditions such as Crohn’s disease and irritable bowel syndrome (IBS), raising the risk of addiction among this population. A review published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology explores newer, potentially safer therapies for treating chronic abdominal pain with lower risks of addiction and side effects.
A team led by Berkeley Lab scientists has developed a process for creating ultrathin, self-assembling sheets of synthetic materials that can function like designer flypaper in selectively binding with viruses, bacteria, and other pathogens. The new platform could potentially be used to inactivate or detect pathogens.
Chemotherapy agents have been associated with neurocognitive side effects in young leukemia survivors. Now St. Jude Children’s Research Hospital scientists have evidence the disease and genetics might also play a role.
A team of researchers at the GW School of Medicine and Health Sciences compared the toxicological impact of cryosurgery with an FDA-approved topical 40 percent hydrogen peroxide solution (A-101) for the treatment of seborrheic keratosis, in human skin equivalents derived from darker skin types. The findings were recently published in the Journal of the American Academy of Dermatology.
Not only can these invasive termites kill pine trees, they also hollow out the trunk of many other trees, including oak trees, making them structurally fragile and susceptible to hurricanes.
Scientists have previously shown that when one animal watches another performing a motor task, such as reaching for food, mirror neurons in the motor cortex of the observer's brain start firing as though the observer were also reaching for food. New Duke research appearing March 29 in the journal Scientific Reports suggests mirroring in monkeys is also influenced by social factors, such as proximity to other animals, social hierarchy and competition for food.
Framework and Principles on Well-Being Aim to Benefit Patients and Strengthen Health Care Systems
Dining out more at restaurants, cafeterias and fast-food outlets may boost total levels of potentially health-harming chemicals called phthalates in the body, according to a study out today.
By detailing the mechanisms underlying the development of medulloblastoma tumors, these findings could lead to new treatments, noted Dr. Mukhopadhyay, a W.W. Caruth, Jr. Scholar in Biomedical Research.
A migraine is much more than just a bad headache. Migraine symptoms, which can be debilitating for many people, are the sixth leading cause of disability, according to the World Health Organization. While there is no cure, a new study published in Cephalalgia in March shows single-pulse transcranial magnetic stimulation is a new way to prevent migraine attacks. It's safe, easy to use and noninvasive.
Special report details serious concerns that medical community would be able to do much, if anything, to assist people in event of major nuclear event. Prevention is best option as well as carefully conceived, long-term plan within the public education system to provide lessons on radiation biology
Michigan State University research says that a blended mix of married and unmarried group members improves creativity, innovation and collaborative thinking.
A team at the Department of Energy’s Oak Ridge National Laboratory has designed and synthesized a selective molecular trap that can separate the minor actinide element americium from a mixture of americium and the lanthanide elements.
A new study looks at what problems affect people most after a stroke and it provides a broader picture than what some may usually expect to see. Stroke affects more than just physical functioning, according to a study is published the March 28, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
By taking a high-cost drug with a low-fat meal—instead of on an empty stomach, as prescribed—prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent.
Optoelectronic engineers have manufactured a special type of LCD that is paper-thin, flexible, light and tough. With this, a newspaper could be uploaded onto a flexible paperlike display that could be updated as fast as the news cycles. It sounds futuristic, but scientists estimate it will be cheap to produce, perhaps only costing $5 for a 5-inch screen. The new optically rewritable LCD design was reported this week in Applied Physics Letters.
Only by increasing the rate at which telescopes monitor the sky has it been possible to catch more Fast-Evolving Luminous Transients (FELTs) and begin to understand them.
UCLA scientists discovered higher levels of a protein called humanin in the placenta tissue of women who give birth to severely underweight infants. The researchers suspect that humanin rises to protect the fetus during placenta failure.
Researchers and public health officials have struggled to explain the resurgence of whooping cough in the United States since the late 1970s, and the suspected shortcomings of the current generation of vaccines are often blamed. But a new University of Michigan-led study concludes that the resurgence of the highly contagious respiratory disease is the result of factors—including a phenomenon known as the honeymoon period—that began in the middle of the last century, long before the latest vaccines were introduced in the late 1990s.
An international research group studying 520,000 people from around the world has identified 22 new genetic risk factors for stroke, tripling the number of gene regions known to affect stroke risk. These results provide new clues on stroke mechanisms and could help scientists identify drug targets for treatment. The work is the largest genetic study on stroke ever.
Observations by NASA's Hubble Space Telescope of galaxy NGC 1052-DF2 have turned up an oddity that sets it apart from most other galaxies, even the diffuse-looking ones. It contains little, if any, dark matter, an invisible substance that makes up the bulk of our universe.
In response to repeated calls for an integrated emergency care system in the U.S., the University of Pittsburgh rose to the challenge and divided the nation into hundreds of referral regions that describe how patients access advanced care, in a way that respects geopolitical borders.
Scientists from the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have developed a way to print 3-D structures composed entirely of liquids. Using a modified 3-D printer, they injected threads of water into silicone oil — sculpting tubes made of one liquid within another liquid.
Scientists at the U.S. Department of Energy’s (DOE) Argonne National Laboratory have published a new study that identifies the process by which holes get trapped in nanoparticles made of zinc oxide, a material of potential interest for solar applications because it absorbs ultraviolet light.
High tide floods, or so-called “nuisance flooding,” that happen along shore roadways during seasonal high tides or minor wind events are occurring far more frequently than ever before. Researchers at the University of New Hampshire have found that in the past 20 years roads along the East Coast have experienced a 90 percent increase in flooding – often making the roads in these communities impassable, causing delays, as well as stress, and impacting transportation of goods and services.
First demonstration of high-pressure metastability mapping with ultrafast X-ray diffraction shows objects aren’t as large as previously thought.
Researchers at the University of Vienna and the Austrian Academy of Sciences develop a new theoretical framework to describe how causal structures in quantum mechanics transform. They analyse under which conditions quantum mechanics allows the causal structure of the world to become "fuzzy". In this case, a fixed order of events is not possible.
New research published in the current issue of the Journal of Personal and Social Relationships shows that the emotional processing of children whose parent argue frequently can be adversely affected, with potentially long term adverse consequences.
By modifying a muscle transplant operation, Johns Hopkins surgeons report they are able to restore authentic facial expressions of joy -- wide and even smiles -- to selected patients with one-sided facial muscle paralysis due to birth defects, stroke, tumors or Bell’s palsy.
Ragweed, its pollen potent to allergy sufferers, might be more than a source of sneezes. In the Midwest, the plant may pose a threat to soybean production.Scientists have found that ragweed can drastically reduce soybean yield.
Using data from male inmates in 23 maximum-security prisons, researchers looked at factors related to fear of rape and likelihood of requesting mental health treatment while incarcerated. They focused on those at most risk of being victimized: gay or bisexual inmates and those with a history of childhood sexual abuse.
In the wake of the 2010 Deepwater Horizon oil spill, University of Florida researchers surveyed people in Gulf coast communities, representing 930 household members, to learn patterns of seafood consumption. A key element needed for this effort was a tool to help survey participants accurately report how much Gulf seafood they actually eat. Anne Mathews, a UF/IFAS assistant professor of food science and human nutrition, led research that examined how accurately people could report their seafood intake, based on photographs of different portion sizes of cooked seafood.
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