GRACILE syndrome, a mitochondrial disease that is part of the Finnish disease heritage, shows altered cell metabolism and proliferation resembling that of cancer cells.
For decades, scientists sought a way to apply the outstanding analytical capabilities of neutrons to materials under pressures approaching those surrounding the Earth’s core. These extreme pressures can rearrange a material’s atoms, potentially resulting in interesting new properties.
An international team of researchers led by marine geoscientist Dr. Jens Karstens of GEOMAR Helmholtz Centre for Ocean Research Kiel has now, for the first time, combined the latest geophysical and geological methods to resurvey the Minoan eruption, which took place 3,600 years ago, of the Greek island of Santorini.
Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. Now scientists at Washington University School of Medicine have identified a potential pathway to pain relief that neither triggers addiction nor causes hallucinations.
Un equipo de astrónomos registró la primera evidencia de una estrella moribunda, similar al Sol, devorando un exoplaneta, gracias a observaciones realizadas con el telescopio de Gemini Sur en Chile, que opera NOIRLab de NSF y Observatorio AURA. La evidencia irrefutable de este evento quedó registrada en un estallido largo y de baja energía de la estrella, un signo revelador de un planeta rozando la superficie de un Sol distante. Este proceso nunca visto antes puede indicar cómo será el destino final de la Tierra cuando nuestro propio Sol alcance el final de su vida en unos 5 mil millones de años más.
Astronomers using the Gemini South telescope in Chile, operated by NSF’s NOIRLab, have observed the first evidence of a dying Sun-like star engulfing an exoplanet. The “smoking gun” of this event was seen in a long and low-energy outburst from the star — the telltale signature of a planet skimming along a star’s surface. This never-before-seen process may herald the ultimate fate of Earth when our own Sun nears the end of its life in about five billion years.
Immunotherapy has redefined cancer treatment, but not all patients experience the same benefit when treated.
Photosynthesis plays a crucial role in shaping and sustaining life on Earth, yet many aspects of the process remain a mystery. One such mystery is how Photosystem II, a protein complex in plants, algae and cyanobacteria, harvests energy from sunlight and uses it to split water, producing the oxygen we breathe. Now researchers from the Department of Energy’s Lawrence Berkeley National Laboratory and SLAC National Accelerator Laboratory, together with collaborators from Uppsala University and Humboldt University and other institutions have succeeded in cracking a key secret of Photosystem II.
Using a “spooky” phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes.
A study conducted in 27 countries, led by the department of Anthropology at the University of California Los Angeles (UCLA) in which the University of Seville takes part, suggests that in the early years of the COVID-19 pandemic, traditionalism was associated with support for stricter precautionary behaviour against the epidemic.
With a view towards predicting the consequences of human-made climate change for Mediterranean ecosystems, Earth scientists from Heidelberg University have studied natural climate and vegetation fluctuations of the past 500,000 years.
Analyzing crowd-sourced sets of data used to create AI algorithms from medical images, University of Maryland School of Medicine researchers found that most did not include patient demographics and none evaluated for inherent biases. That means they have no way of knowing whether these images contain representative samples of the population such as Blacks, Asians, and Indigenous Americans.
An international team of scientists led by a University of Houston physicist and several of his former students has reported a new approach to constructing the thermoelectric modules, using silver nanoparticles to connect the modules’ electrode and metallization layers.
What if your physician could predict if—or when—you might experience a heart attack, cardiac arrest or another heart-related problem?
Fusion energy researchers use a technique called Gas-Puff Imaging (GPI) to visualize an important phenomenon in tokamak devices involving turbulence in plasma magnetic confinement fields. This technique can generate roughly 1 million frames of visual data, far too much for humans to analyze by eye. Scientists recently tested a machine-learning based approach for analyzing GPI images. The system provides detailed, time- and space-resolved information and could aid in design and operation of future fusion power devices.
New research found that Americans already bearing the brunt of climate change and health inequities are most at risk of impact by a lengthy power outage.
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Colistin is a last-resort antibiotic critical for treating multidrug-resistant bacterial infections. Resistance to colistin heralds the emergence of truly pan-resistant infections. In the article, the researchers found combining colistin with inhibitors of biotin (vitamin B7) or fatty acid production can overcome colistin resistance.
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A team of scientists from the U.S. Department of Energy’s Ames National Laboratory demonstrated a way to advance the role of quantum computing in materials research with an adaptive algorithm for simulating materials. Quantum computers have potential capabilities far beyond today’s computers, and using an adaptive algorithm allows them to produce solutions quickly and accurately.
A breakthrough study by researchers from Bar-Ilan University establishes the first physics laboratory benchmark for the manifestation of the theory of interdependent networks, enabling experimental studies to control and to further develop the multiscale phenomena of complex interdependent materials. This research has vast significance in several disciplines, including basic physics, materials science and device applications.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for April 2023.
Researchers led by Dr. XIN Liping from the Space-based Multi-band Astronomical Variable Objects Monitor (SVOM) research team, National Astronomical Observatories of the Chinese Academy of Sciences (NAOC), have detected the prompt optical emission and its transition to the early afterglow of a gamma-ray burst (GRB 201223A), using the Ground Wide Angle Camera Array (GWAC) located at Xinglong Observatory of NAOC.
A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach could also power the development of advanced cell therapies for cancers and other diseases, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.
A research team has developed a completely new magnetic resonance imaging (MRI) approach. Using a harmless glucose solution, the procedure generates reliable results and – in principle – can be used with all common MRI scanners.
In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One such is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes an initial signal for the reading of DNA.
Mass adoption of perovskite solar cells will never be commercially viable unless the technology overcomes several key challenges, according to researchers from the University of Surrey.
Life in the ocean’s “twilight zone” could decline dramatically due to climate change, new research suggests.
Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells. These plasma cells are a special type of white blood cells that play an important role in the immune system by producing essential antibodies in the bone marrow and lymph nodes.
Habitats suitable for Asian elephants (Elephas maximus) across Asia have decreased by over 64% – equating to 3.3 million square kilometres of land – since the year 1700, estimates a study published in Scientific Reports.
A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A). This structure and other findings in the new study could be harnessed to engineer new BoNT/E variants with modified specificities toward different SV2 isoforms for new clinical developments.
An international team of researchers led by Prof. MA Keping from the Institute of Botany of the Chinese Academy of Sciences (IBCAS) has shown that forests with higher tree species richness tend to have greater arthropod diversity.
Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors. By visualizing how the genome is organized and arranged within tumor cells, they were able to reveal genes in tumors that may be future targets for therapy. The results appear in Nature Communications.
Researchers have found a way to replicate in a non-living system a behavior often found in living ones. This could be the secret to more efficient organic semiconductors for electronic devices.
Among families with children diagnosed with autism spectrum disorder, Johns Hopkins University researchers say they have found a link between chemical “marks” on DNA in the sperm of fathers and autistic traits in their 3-year-old children.
Most medical AI models in use today are trained to perform one or two specific tasks and have limited utility.
Safer and more effective blood thinners could be on the way following a groundbreaking discovery by researchers at UBC and the University of Michigan, published today in Nature Communications.
Some things are related, others are not. Suppose you randomly select a person from a crowd who is significantly taller than the average. In that case, there is a good chance that they will also weigh more than the average.
Researchers design “mini gene” therapy for severe syndrome that causes blindness and deafness
Experts in nuclear physics and quantum information have demonstrated the application of a photon-number-resolving system to accurately resolve more than 100 photons. The feat is a major step forward in capability for quantum computing development efforts. It also may enable quantum generation of truly random numbers, a long-sought goal for developing unbreakable encryption techniques for applications in, for instance, military communications and financial transactions.
Keeping tree diversity intact in Canada’s many forests over the long term can help increase carbon capture and mitigate climate change, according to a new University of Alberta study.
New research from a multidisciplinary team at Cornell helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.
Scientists studying the supermassive black hole at the heart of the M87 galaxy have revealed the origins of the monster’s powerful jet and imaged the jet and its source together for the first time. What’s more, the observations have revealed that the black hole’s ring is much larger than scientists previously believed.
A gene in the brain driving anxiety symptoms has been identified by an international team of scientists. Critically, modification of the gene is shown to reduce anxiety levels, offering an exciting novel drug target for anxiety disorders. The discovery, led by researchers at the Universities of Bristol and Exeter, is published online today [25 April] in Nature Communications.
Un equipo científico que estudió el agujero negro supermasivo presente en el corazón de la galaxia M87 reveló los orígenes de su poderoso chorro y logró obtener las primeras imágenes del chorro y su fuente juntos. Las observaciones también revelaron que el anillo del agujero negro es mucho más grande de lo que la comunidad científica creía.
The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.
A world-first trial at UCL and UCLH has found a new genetic therapy for Alzheimer’s disease that is able to safely and successfully lower levels of the harmful tau protein known to cause the disease.
A study just released by Columbia Mailman School of Public Health and Peking University School of Public Health provides some of the first, large-scale evidence that processes of biological aging may contribute to risk of depression and anxiety.
A team of international researchers led by Federico Baltar of the University of Vienna and José M González of the University of La Laguna has identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters. The results have now been published in the journal Nature Microbiology.
Mangrove forests are an essential component of the coastal zones in tropical and subtropical areas, providing a wide range of goods and ecosystem services that play a vital role in ecology. They are also threatened, disappearing, and degraded across the globe.
A large-scale registry study in Finland has identified several factors associated with uptake of the first dose of COVID-19 vaccination. In particular, persons with low or no labor income and persons with mental health or substance abuse issues were less likely to vaccinate.
The discovery shows why it can be so difficult to tackle drug-resistant bacteria, but does provide a possible avenue for tackling the problem.
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