Researchers at The Methodist Hospital Center for Cardiovascular Disease Prevention and the Baylor College of Medicine presented new data today that show two biomarkers can improve heart failure risk prediction as part of a simpler model.
A landmark study could lead to fewer inappropriate shocks from implanted defibrillators.
Heart failure patients with a condition called “heart block” derive significant benefit from cardiac resynchronization therapy (CRT), according to the results of the Block HF clinical trial, presented today at the American Heart Association Scientific Sessions 2012 meeting in Los Angeles.
An international, clinical research trial has shown that patients with diabetes whose multi-vessel coronary artery disease is treated with bypass surgery live longer and are less likely to suffer severe complications like heart attacks than those who undergo angioplasty.
Research by Johns Hopkins cardiologists suggests that electrocardiograms (ECGs), which are widely used tests to assess the heart’s electrical activity, may have a greater and more profound future role in predicting the risk of death from any cause, not just heart problems. In a study initially designed to determine which patients with heart failure were at highest risk of a dangerous heart rhythm disorder called ventricular tachycardia, and death, the researchers analyzed the ECGs of 850 patients using a new computer algorithm that detects abnormal heart rate patterns. They found a significant correlation between the ECG findings using the special analysis and the patients who died within five years of the test.
Black men and women have twice the risk of fatal coronary heart disease as whites, but the disparity could be eliminated with better risk factor control.
Hispanics and Latinos living in the U.S. are highly likely to have several major cardiovascular disease risk factors, such as high cholesterol, high blood pressure, obesity, diabetes, and smoking, according to a new, large-scale study.
Anesthesiology residents may not be prepared to manage rare but life-threatening emergencies involving cardiac arrest during labor and delivery, suggests a stimulation study in the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).
Cognitive functions improve significantly after four months of high-intensity interval training program in middle-aged people with increased cardiovascular risk.
Results of a large-scale, randomized clinical trial called RESPECT revealed that patent foramen ovale (PFO) closure is superior to medical therapy in preventing recurrent stroke, according to a presentation of findings today at the TCT conference.
A gene known to be involved in cancer and cardiovascular development may be the cause of inflammation in the most common form of aortic aneurysm and may be a key to treatment, according to research from Nationwide Children’s Hospital. The study, appearing online in Arteriosclerosis, Thrombosis, and Vascular Biology on October 18, 2012, is the first to show that Notch 1 signaling is activated in abdominal aortic aneurysmal tissue in mice and humans.
Among nearly 45,000 men who were followed up for more than two decades, those with the risk factors of smoking, hypertension, high cholesterol, and type 2 diabetes had an associated greater risk of developing PAD.
• Kidney failure patients have less sugar coating along the insides of their blood vessels, and they have high levels of the coating’s constituents in the blood, consistent with increased shedding. • Damage to this sugar coating may be responsible for kidney failure patients’ increased risks of heart problems. Heart disease is the number one killer of individuals with kidney disease.
Exercise helps attenuate the premature cardiovascular aging that type 2 diabetes can cause. Findings being discussed at the Integrative Biology of Exercise VI meeting, co-sponsored by the American Physiological Society.
Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University.
A new study conducted by researchers in the Cardiac and Vascular Institute at NYU Langone Medical Center, found using beta-blockers, the standard of care for patients with coronary artery disease (CAD), was not associated with a lower risk of heart attacks, death and strokes in patients suffering from CAD and those with risk factors for the disease, including those with a history of heart attack. The study appears in the October 3 issue of JAMA (Journal of the American Medical Association).
Among patients with either coronary artery disease (CAD) risk factors only, known prior heart attack, or known CAD without heart attack, the use of beta-blockers was not associated with a lower risk of a composite of cardiovascular events that included cardiovascular death, nonfatal heart attack or nonfatal stroke
Since moderate drinking is common for more than a third of the population, the findings suggest the effect of increased alcohol consumption, even in moderate amounts, on atrial fibrillation risk in patients with pre-existing cardiovascular disease may be considerable.
Researchers at the Sainte-Justine University Hospital Center and University of Montreal have identified genetic origins in 10% of an important form of congenital heart diseases by studying the genetic variability within families.
Atherosclerosis has been presumed to be the consequence of complicated interactions between overabundant cholesterol and resulting inflammation in the heart and blood vessels. Researchers at the University of California, San Diego School of Medicine, with colleagues at institutions across the country, say the relationship is not exactly what it appears, and that a precursor to cholesterol actually suppresses inflammatory response genes. This precursor molecule could provide a new target for drugs designed to treat atherosclerosis.
Sleep-related breathing problem associated with serious, expensive conditions like preeclampsia, gestational hypertension.
Despite rapid adoption of dabigatran for the treatment of atrial fibrillation, a large proportion of patients did not receive oral anticoagulant therapy and an increasing proportion of use was for off-label indications.
Subclinical hyperthyroidism is not associated with overall or cardiovascular mortality, according to new data presented at the 82nd Annual Meeting of the American Thyroid Association (ATA) in Québec City, Québec, Canada.
A form of pterostilbene, a compound found naturally in blueberries, reduces blood pressure in adults, according to results of a clinical trial presented at the American Heart Association’s 2012 Scientific Sessions on High Blood Pressure Research.
A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.
In a study that included nearly 70,000 patients, supplementation with omega-3 polyunsaturated fatty acids was not associated with a lower risk of all-cause death, cardiac death, sudden death, heart attack, or stroke, according to an analysis of previous studies published in the September 12 issue of JAMA.
University of Maryland School of Medicine researchers have found that cardiac stem cells (CSCs) from newborns have a three-fold ability to restore heart function to nearly normal levels compared with adult CSCs. Further, in animal models of heart attack, hearts treated with neonatal stem cells pumped stronger than those given adult cells.
Even though African American men in the United States are disproportionately more likely to have uncontrolled high blood pressure (or hypertension) than other racial and ethnic groups, they are less likely to take health-preserving medication.
The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of hypertriglyceridemia. Triglycerides are a type of fat found in the blood and are associated with cardiovascular risk.
An estimated 2.5 million Americans suffer from irregular heartbeats-also known as atrial fibrillation. The incidence of this potentially life changing cardiovascular condition is on the rise and expected to more than double by 2050.
Untreated severe obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular mortality in the elderly, and adequate treatment with continuous positive airway pressure (CPAP) may significantly reduce this risk, according to a new study from researchers in Spain.
Researchers at the Perelman School of Medicine at the University of Pennsylvania report in a new study that thickening of the heart’s right ventricle is associated with an increased risk of heart failure and cardiovascular death in patients without clinical cardiovascular disease at baseline. The study is published online ahead of print in the journal Circulation.
Florida State University researchers led by physics doctoral student Campion Loong have achieved significant benchmarks in a study of the human cardiac protein alpha-tropomyosin, which is an essential, molecular-level component that controls the heart’s contraction on every beat. Using an imaging method called atomic force microscopy, Loong achieved two “firsts”: the first direct imaging of individual alpha-tropomyosin molecules and the first demonstrated examples of a measure of the human cardiac protein’s flexibility.
Atrial fibrillation is a common complication of cardiac surgery, occurring in 10 percent to 40 percent of patients. Recent studies show it to be associated with poorer health following surgery and poorer long-term survival.
The purpose of the Princeton III meeting was to find an approach for optimizing sexual function and preserving cardiovascular health in men with known cardiovascular disease and to develop a primary approach to cardiovascular risk assessment in younger men with erectile dysfunction and no cardiovascular disease. The conference updated findings from the Princeton I and Princeton II meetings, held in 2000 and 2005, respectively.
People who are of normal weight but have fat concentrated in their bellies have a higher death risk than those who are obese, according to Mayo Clinic research presented today at the European Society of Cardiology Congress in Munich. Those studied who had a normal body mass index but central obesity — a high waist-to-hip ratio — had the highest cardiovascular death risk and the highest death risk from all causes, the analysis found.
Stroke is the fourth leading cause of death and a common cause of long-term disability in the United States, but doctors have very few proven treatment methods. Now a new device that mechanically removes stroke-causing clots from the brain is being hailed as a game-changer.
New study results call for better screening for diabetes, heart disease.
A study of adults >50 years old has found no lasting adverse effects from running marathons, similar to findings of adults aged 18-40.
Strong scientific evidence suggests that high levels of a blood protein called galectin-3 may increase the risk of heart attacks, cancer and other diseases, and help forecast the outcome of those diseases, a scientist reported here today at the 244th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.
Each year, hundreds of thousands of X-rays are performed across the country to help detect and treat common cardiovascular conditions such as coronary artery disease, valve disease and other heart problems. However, concern is growing within the medical community about the potential risks of radiation exposure from this imaging technology. Now, researchers at Mayo Clinic have been able to dramatically cut the amount of radiation that patients and medical personnel are exposed to during invasive cardiovascular procedures. The solution: targeted modifications to the use of standard X-ray equipment, coupled with intensive radiation safety training. The efforts are detailed in a paper published online Aug. 20 in the Journal of the American College of Cardiology: Cardiovascular Interventions.
Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than one thousand men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
A new study finds that treating chronic venous leg ulcers with a topical spray containing a unique living human cell formula provides a 52 percent greater likelihood of wound closure than treatment with compression bandages only.
Patients with chronic heart failure who participated in exercise training had modest reductions in symptoms of depression after 12 months, compared with usual care
Although there have been questions regarding the safety and durability of endoscopic vein graft harvest for coronary artery bypass graft (CABG) surgery, an analysis of data of more than 200,000 patients who underwent CABG surgery found no evidence of a long-term increased risk of death with endoscopic vein graft harvesting compared to open vein-graft harvesting
JAMA study using STS National Database shows a minimally invasive vein harvesting approach used during heart surgery is as safe as a more invasive vein harvesting procedure while also leading to fewer complications. The FDA requested that the STS National Database be used for this study because it is the premier clinical data registry for cardiothoracic surgery. The study’s senior author is Dr. Peter Smith from Duke. The spokesperson for the STS National Database is Dr. Fred Edwards, who is also an author of the study.
Researchers at UCLA have identified a novel molecule in the brain that, after stroke, blocks the formation of new connections between neurons. As a result, it limits the brain’s recovery. In a mouse model, the researchers showed that blocking this molecule—called ephrin-A5--induces axonal sprouting, that is, the growth of new connections between the brain’s neurons, or cells, and as a result promotes functional recovery.
A study conducted by researchers from the University of California, San Diego School of Medicine along with colleagues from Rural/Metro Ambulance San Diego and the San Diego Fire-Rescue Department, shows that emergency medical personnel can obtain an electrocardiogram (ECG) in the field for chest pain patients without an increase in scene time or transport time to the hospital.
Patients suffering from the chronic lung condition COPD, which is the third-leading cause of death and disability in the United States, may benefit greatly from a three-times-a-week dose of an antibiotic, according to a study by Virginia Commonwealth University physicians published in today’s issue of the New England Journal of Medicine.
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