Breakthrough research demonstrating that children with autism as young as 18 months can vastly improve their language, cognition and social skills with an early intervention developed by UC Davis Professor Sally Rogers has been replicated in a major new study.
A list of Leading Research Achievements by Brain & Behavior Research Foundation Grantees in 2018.
Researchers find brain overconnectivity in the unimodal-subcortical connections and brain underconnectivity in the supramodal-subcortical connections for ASD individuals, as compared to a typically developing control group, suggesting a relationship between connectivity and the expression of ASD.
In a study published January 17, 2019 in Translational Psychiatry, researchers at University of California San Diego School of Medicine describe how, in a novel mouse model, epigenetic regulation negatively impacts a downstream gene specifically involved in neurodevelopment and associated behaviors.
Irvine, Calif., Jan. 23, 2019 — Online publishing platforms and digital media can provide opportunities for nonmainstream groups to push back against and offer alternatives to the simplistic stereotypes presented in literature and popular culture. A study led by the University of California, Irvine focused on Harry Potter fan fiction and discovered that autistic people, family members, teachers and advocates cast autistic characters in their stories in diverse ways that challenge typical representations.
Researchers at the University of Utah Health conducted the first population-based study of suicidality in individuals with ASD in the United States. The 20-year retrospective study found that for individuals with autism, particularly females, the risk of suicide has increased through time compared to their non-autistic peers.
In a study published online today in the journal Science, researchers at Albert Einstein College of Medicine, part of Montefiore, prove for the first time that the brain’s cerebellum—long thought to be mainly involved in coordinating movement—helps control the brain’s reward circuitry. The surprising finding indicates that the cerebellum plays a major role in reward processing and social behaviors and could potentially lead to new strategies for treating addiction.
Researchers at Children’s Hospital of Philadelphia (CHOP) evaluated a digital medicine tool designed as an investigational treatment for children with autism spectrum disorder (ASD) and co-occurring attention/deficit-hyperactivity disorder (ADHD).
Seaver Autism Center study results contribute to understanding of patterns of cognitive functioning in adults with autism and highlight the importance of a broader approach when studying cognition
A community-based, pilot study shows a high-tech app is as effective as low-tech picture card intervention at improving social and communication skills in children with autism.
Two studies have linked DNA changes to their molecular effects in the brain, revealing new mechanisms for psychiatric diseases. The findings provide a roadmap for developing a new generation of therapies for conditions like autism, schizophrenia and bipolar disorder.
Saint Joseph’s University is one of the first higher education institutions to offer an Autism Break Room in an NCAA Division I athletic arena
Dr. Meghan Miller of the UC Davis MIND Institute talks about her paper, published in JAMA Pediatrics, about the risk of younger siblings of children with autism or ADHD for either or both disorders.
Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for both disorders, a new study led by Meghan Miller, assistant professor in the Department of Psychiatry and Behavioral Sciences and at the UC Davis MIND Institute, has concluded. The findings appear today in JAMA Pediatrics.
UAB study suggests individuals diagnosed with autism spectrum disorder may not be more prone to cyber phishing attacks compared to those without the disorder.
An international team of scientists, led by researchers at the University of Cyprus and University of California San Diego School of Medicine, have identified a previously unknown, large-scale association between molecular gene expression activity in blood leukocyte cells and altered neural responses to speech in toddlers with autism as measured with functional magnetic resonance imaging.
For decades, scientists have examined how regions of the brain communicate to understand autism. Researchers at University of Utah Health believe the symptoms of autism may result from sustained connections between regions of the brain.
What if we could observe genes firing off signals to cause some behaviors? We're getting closer. Researchers were able to directly match gene regulation with ritual mating behavior in fish. Their research field may also give some insight into autism spectrum disorder.
In one of the largest school-based clinical trials of its kind, researchers at the Institute for Autism Research at Canisius College found an innovative, comprehensive school treatment (schoolMAX) yields significant improvements for elementary-school children with autism spectrum disorder (ASD)
Improved communication skills may be linked to increased connectivity between auditory and motor regions of the brain, researchers at Université de Montreal and McGill University find.
Research on autism spectrum disorder in older adulthood lags significantly behind that of research in other age groups. A Canisius research team was awarded a federal grant to better understand the life outcomes of adults with autism spectrum disorder.
New method developed by Mount Sinai team allows systematic study of effects of a wide range of drugs on the developing fetus
The Michael & Susan Dell Center for Healthy Living, part of The University of Texas Health Science Center at Houston (UTHealth), announced today a new plan to create a statewide network of researchers, decision-makers, and other key representatives that will give increased access to evidence-based solutions and data.
Saint Joseph’s University announced the appointment of Angus Murray, a seasoned nonprofit leader with deep experience in supporting children and young adults with autism and disabilities, as executive director of the Kinney Center for Autism Education and Support, effective November 5.
A new study reveals that children with developmental delays, including autism spectrum disorder (ASD), are up to 50 percent more likely to be overweight or obese compared with the general population.
The Gonzaga University Exceptional Bulldogs Hockey program will expand and help more youth overcome learning and communications difficulties thanks to donations from The Isaac Foundation — allowing it to become part of the Spokane Youth Hockey Association
Scientists have uncovered a brain-signaling pathway that can be pharmacologically manipulated in genetically engineered mice to reverse an autism-related pathway. Using an experimental drug targeting this pathway, the researchers normalized the disrupted physiology and behavior of these mice. Moreover, effects were seen in adult mice, suggesting a possible route to medication development for adults with autism spectrum disorder.
A Rutgers University–New Brunswick-led team of researchers is calling for the creation of a global microbiota vault to protect the long-term health of humanity. Such a Noah’s Ark of beneficial germs would be gathered from human populations whose microbiomes are uncompromised by antibiotics, processed diets and other ill effects of modern society, which have contributed to a massive loss of microbial diversity and an accompanying rise in health problems. The human microbiome includes the trillions of microscopic organisms that live in and on our bodies, contributing to our health in a myriad of ways.
Researchers at the UC Davis MIND Institute and the University of North Carolina have shown for the third time that an increased amount of extra-axial cerebrospinal fluid (CSF) is associated with the diagnosis of autism spectrum disorder in young children. The ability to identify ASD children early could improve both treatment and quality of life. The study was published in the journal The Lancet Psychiatry.
New state autism center opens at Rutgers to improve research, treatment and family services
Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have developed new single-cell approaches wedded to machine learning. This has revealed thousands of previously unknown DNA changes arising during prenatal life in the developing mouse brain. The study published today in PNAS.
Researchers at Rensselaer Polytechnic Institute—led by Juergen Hahn, professor and head of biomedical engineering—are continuing to make remarkable progress with their research focused on autism spectrum disorder (ASD).
A professor at UTHealth in Houston is testing the hypothesis that probiotics can help improve gastrointestinal symptoms of children with autism spectrum disorder (ASD).
A West Virginia University graduate student is studying how certain cells affect the development of this part of the brain, and therefore, how they could affect how quickly and accurately the brain processes sounds.
Progress in treating chronic illness, where the cause of the problem is often unknown, has lagged. Chronic conditions like cancer, diabetes and cardiovascular disease defy easy explanation, let alone remedy. In a new paper, a researcher at University of California San Diego School of Medicine, posits that chronic disease is essentially the consequence of the natural healing cycle becoming blocked, specifically by disruptions at the metabolic and cellular levels.
Childhood obesity is a serious public health concern that can have a profound impact on children’s health and well-being. Children with Autism Spectrum Disorder (ASD) are more likely to have obesity compared to their peers with typical development, data show
Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD). Part of the Children’s Autism Metabolome Project (CAMP), the largest metabolomic ASD study ever attempted, these findings are a key step toward developing an ASD biomarker test. The research was published September 6 in the journal Biological Psychiatry.
The latest research, features and announcements in healthcare in the Healthcare News Source
Temple Grandin, a renowned expert on animal behavior and activist for people with autism, is coming to Iowa State University on Sept. 13.
Rush University Medical Center and the Angelman Syndrome Foundation (ASF), a national nonprofit organization headquartered in Aurora, Ill., announced the official opening of the Angelman Syndrome Clinic at Rush Children’s Hospital. The Angelman Syndrome Clinic at Rush is the first and only in Illinois and one of only eight in the U.S.
Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children. The findings, published in Nature Genetics, identify mutations in the alpha-N-catenin gene, (aka CTNNA2), which promotes cell adhesion and causes pachygyria, one of the most serious developmental brain defects in humans. Most patients are severely intellectually impaired, and are unable to walk or care for themselves. Children diagnosed with the rare disease have a life expectancy of about 10 years.
Scientists have designed a way to monitor cellular decision making by measuring the rate of RNA change over time. RNA is the “interpreter” or “decoder” of genetic instructions that tell cells how much of which protein to make. The new method is an algorithm that quantifies changes in various RNA markers—the molecular footprints of a cell’s past and present and an indicator of its future, providing clues about what the cell is trying to become. The approach sets the stage for understanding cellular behavior during human development and may offer a way to rapidly monitor how cells respond to medications and other treatments.
Researchers have found a surprising way to help boost the skills of children with language impairment: Pay their parents to read to them.
With more than $2 million from the National Institute of Neurological Disorders and Stroke, a team at GW led by Chiara Manzini, PhD, will study the CC2D1A gene and its role in the development of autism in males versus females.
A mother’s microbiome, the collection of microscopic organisms that live inside us, determines the risk of autism and other neurodevelopmental disorders in her offspring, new research from the UVA School of Medicine shows. The research suggests that we may be able to prevent autism just by altering an expectant mother's diet or by giving her custom probiotics.
Researchers at the Institute for Autism Research (IAR) at Canisius College were awarded an $880,431 grant from the U.S. Department of Education, Institute of Education Sciences (IES), to fully fund a three-year study of the long-term beneficial impacts from an innovative school intervention for high-functioning children with autism spectrum disorder (HFASD) developed by the IAR research team.
Exposing newborn mice to vaginal microbes from stressed female mice may transfer the effects of stress to the newborns, according to a new study by researchers at the University of Maryland School of Medicine. These changes resemble those seen specifically in the male offspring of moms that were stressed during pregnancy.
Sex plays a role in hypertension, diabetes, arthritis – and in many neurological and psychiatric disorders. To better understand the molecular underpinnings of this disparity, Tracy Bale of the University of Maryland School of Medicine, along with several colleagues, focused on a molecule that plays a key role in placental health. In a study of mice, they found that the molecule, O-linked N-acetylglucosamine transferase (OGT) works by establishing sex-specific patterns of gene expression.
Can a new mouse model provide essential insights into one type of autism spectrum disorder? UC Davis researchers hope their work yields new therapies for children.
Special training for teachers may mean big results for students with autism spectrum disorder, according to Florida State University and Emory University researchers.
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