Researchers have gained new insights into the virus that causes hepatitis B – a life-threatening and incurable infection. The discovery reveals previously unknown details about the shell of the vigenetic blueprint and could lead to new drugs to treat the infection.
Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta — the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer’s disease.
Two chemistry researchers from Missouri University of Science and Technology are part of an international team that has designed a new metal-organic framework that exhibits dramatic improvements in electron mobility, which could lead to new applications for fuels cells, batteries and other technologies.
A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.
Today two experiments at the Large Hadron Collider announced a discovery that finally links the two heaviest known particles: the top quark and the Higgs boson. The CMS and ATLAS experiments have seen simultaneous production of both particles during a rare subatomic process.
A study by UNC Lineberger Comprehensive Cancer Center's Ronald Chen, MD, MPH, and colleagues assessed whether monitoring prostate cancer patients following treatment with a PSA test every three months versus once a year would provide a long-term survival benefit.
A new study suggests, for the first time in women over age 70, that working up a sweat can reduce the influence one’s genes have on obesity.
Globular clusters could be up to 4 billion years younger than previously thought, new research led by the University of Warwick has found.
In a new article published in the journal Philosophical Transactions of the Royal Society B, Donald Behringer and one of his co-authors, post-doctoral researcher Jamie Bojko, both of the UF Institute of Food and Agricultural Sciences, point out many ways organisms try to escape diseases.
The ancient people of Easter Island, or Rapa Nui, were able to move massive stone hats and place them on top of statues with little effort and resources, using a parbuckling technique, according to new research from a collaboration that included investigators from Binghamton University, State University at New York.
Rutgers Global Health Institute’s director discusses how rejecting scientific facts can undermine progress in public health – and how the medical profession can further public understanding of science
n a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women’s acne.
Vaccinating asthmatic pre-schoolers against influenza could dramatically reduce their risk of being hospitalized after an attack, Canadian researchers find.
A 21-gene test could enable most patients with the most common type of early breast cancer to safely forgo chemotherapy, according to a landmark study published in the New England Journal of Medicine. Loyola Medicine oncologist Kathy Albain, MD, is among the main co-authors.
Want to improve your attention? Washington University in St. Louis brain sciences researcher Richard Abrams finds that our attention may be guided by the most recent interactions with our environment.
Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease.
Research to be presented at the ASCO 2018 Annual Meeting suggests that a new treatment combination can extend survival for many patients with advanced colorectal cancer and that its efficacy compares favorably to single-agent approaches.
In a small Phase II study of early-stage breast cancer patients with BRCA1/2 mutations, researchers at The University of Texas MD Anderson Cancer Center found that more than half of the women who took the PARP inhibitor talazoparib once daily prior to surgery had no evidence of disease at the time of surgery. If further validated in larger, confirmatory trials, the oral medication could replace chemotherapy for these patients.
Researchers at Brazil's largest producer of antivenoms report a structural analysis of glycans modifying venom proteins in several species of lancehead viper. The snakes are among the most dangerous in South America. The report offers insight into the solubility and stability of toxic proteins from venom, and into how venoms from different species vary. Scientists are now working to map glycan structures back onto the proteins they modify.
In a study published in the May 21, 2018 issue of the Proceedings of the National Academy of Sciences, a team of researchers – aided with supercomputing resources from the San Diego Supercomputer Center (SDSC) based at UC San Diego – created a dynamic computer simulation to delineate a key biological process that allows the body to repair damaged DNA.
روتشستر، مينيسوتا. - يعرف المصابون بالصداع النصفي جميعهم جيدًا أن ألم الخفقان المرتبط بهذا الصداع يمكن أن يكون شديدًا وموهنًا. ولا يتساوى الأمر كله بين الجنسين عندما يتعلق الأمر بهذه النوبات التي تعوق الفرد عن ممارسة حياته الطبيعية. حيث تُظهر الأبحاث أن الصداع النصفي أكثر شيوعًا ثلاث مرات لدى النساء منه لدى الرجال.
Penn study finds value in collecting patients’ sexual orientation and gender identity, but cautions medical providers from drawing conclusions based on that information alone
Researchers have devised a magnetic control system to make tiny DNA-based robots move on demand--;and much faster than recently possible.
Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.
A new study shows a rapid rise in the percentage of hospitals that require their workers to be vaccinated against influenza – except among hospitals that focus on treating the nation’s military veterans. The percentage of Veterans Affairs hospitals that have a flu vaccine mandate rose from 1 percent in 2013 to 4 percent in 2017. But at the same time, the percentage of non-VA hospitals requiring shots rose from 44 percent to nearly 70 percent.
Researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.
More than half of high school baseball pitchers report experiencing pain in their throwing arms during the season. To better understand the cause of these injuries, researchers at The Ohio State University Wexner Medical Center conducted a new study to determine when and why overuse injuries are occurring.
Waste heat can be converted to electricity more efficiently using one-dimensional nanoscale materials as thin as an atom – ushering a new way of generating sustainable energy – thanks to new research by the University of Warwick.Led by Drs Andrij Vasylenko, Samuel Marks, Jeremy Sloan and David Quigley from Warwick’s Department of Physics, in collaboration with the Universities of Cambridge and Birmingham, the researchers have found that the most effective thermoelectric materials can be realised by shaping them into the thinnest possible nanowires.
A direct brain-to-computer interface may be on the horizon. New insights into how quickly microorganisms break down organic matter in warming Arctic soil. Using liquid salt that contains FLiBe to cool molten salt reactors. Compact, powerful solar.
A six-step bundle published in Critical Care Nurse offers bedside nurses and other members of the interprofessional team a comprehensive, step-by-step approach to early nutrition. The bundle reinforces new guidelines from the American Society of Parenteral and Enteral Nutrition.
Autism screening app is a novel, parent-friendly, and scalable way to collect scientifically valid data.
Some people argue that animals have personalities: shy, bold, aggressive.It’s more than just cocktail party conversation for anole lizards, whose risk-taking behavior can mean the difference between life and death.For anoles in the Caribbean islands, natural selection predictably favors exploratory behavior in the absence of predators, and ground avoidance when predators are around, according to a new experimental field study in the June 1 issue of Science.
Immunosuppressed patients with sepsis appear more likely to die if they are treated in a hospital caring for a relatively small number of these patients, according to new research published online in the Annals of the American Thoracic Society.
With more than 20 “red flag” gun bills pending in state legislatures, risk-based gun seizure laws have emerged as a prominent policy option for reducing gun violence. A new study by Aaron Kivisto of the University of Indianapolis--appearing in the June edition of the journal Psychiatric Services--provides evidence that risk-based gun seizure laws do work and are saving lives.
Researchers from the University of California, Irvine School of Medicine, in collaboration with scientists at UCSF and Northwestern University, have profiled human breast epithelial cells, identifying three new distinct epithelial cell populations. The discovery of these cell populations could aid in understanding the origins of breast cancer and lead to improved early cancer detection, a slowing of cancer progression and possibly even cancer prevention.
In a statement published in the European Respiratory Journal, a coalition of respiratory doctors and scientists from six continents have warned of the dangers posed to children and adolescents by electronic cigarettes [1].
The American Society of Clinical Oncology has chosen Ralph Weichselbaum, Chair of Radiation and Cellular Oncology, Co-Director of the Ludwig Center for Metastasis Research at Univ. of Chicago, to receive the 2018 Karnofsky Award and present the Karnofsky Lecture, a high point of the meeting, on Sat., June 2.
Cancer is one of the leading causes of death among Americans. At least 10 percent of cancers are caused by inherited mutations in genes such as BRCA1 and BRCA2. Parents with the cancer gene mutation have a 50 percent chance of passing it on to a son or daughter. It’s well-known that women with BRCA are at a very high risk for breast and ovarian cancer.
• Among living kidney donors, the post-donation concern that was considered most important was kidney health, followed by the surgical, lifestyle, functional, and psychosocial impacts of donation. • The hypothetical long-term risks associated with kidney removal—including mortality and cardiovascular disease—were of relatively lower importance.
Two Mississippi State physicists are seeing more than a decade of research yield a new high-precision result that will expand scientists’ knowledge of the weak force in protons. Published this month in the international journal of science, Nature, the Q-weak project conducted by the Jefferson Lab Q-weak Collaboration sought to precisely measure the proton’s weak charge, a quantity that signifies the influence the weak force exerts on protons. MSU Professors James Dunne and Dipangkar Dutta have worked with the consortia since 2004 and 2006, respectively.
Study reveals surprising, bad chemical reactivity in battery components previously considered compatible.
Mount Sinai researchers investigate transcriptome-wide alterations in response to cocaine self-administration in mice
Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.
Detecting patterns is an important part of how humans learn and make decisions. Now, researchers have seen what is happening in people’s brains as they first find patterns in information they are presented.
Symptoms associated with borderline personality disorder — a severe and chronic mood disorder characterized by an inability to manage strong emotions — tend to worsen just before and during menses, according to a study in Psychological Medicine.Borderline personality disorder is a mental illness marked by an ongoing pattern of varying moods, self-image and behavior, according to the National Institute of Mental Health.
An international team of researchers has found a new way to investigate how tuberculosis bacteria inactivate an important family of antibiotics: They watched the process in action for the first time using an X-ray free-electron laser, or XFEL.
Supercomputer simulations of neutrons' inner turmoil and a new method that filters out "noise" yield the highest-ever precision calculation of nucleon axial coupling, a property crucial to predicting neutron lifetime.
Three brain development genes are found only in humans and may have helped drive the rapid expansion of the brain starting roughly three million years ago.
Child care, parenting and child health/health care are important factors in improving the lives of children in low-income families, according to a new study from the Brown School at Washington University in St. Louis. Researchers conducted a national survey of staff at helplines where consumers dial 211 for community information and referral services.
As the first step toward predicting cerebral palsy in premature infants, scientists have identified a panel of microRNAs that are changed in babies who later develop abnormal muscle tone. MicroRNAs are small, noncoding RNA molecules that are important regulators of gene expression affecting developmental processes. Searching for microRNAs that could serve as early biomarkers – biological signs of disease – scientists for the first time have demonstrated that it is feasible to evaluate over 750 microRNAs using only one-half milliliter of blood collected from babies weighing less than 1500 grams (or under three pounds). Results were published in Physical Medicine and Rehabilitation – International.
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