An innovative book distribution program that provides free children’s books in low-income neighborhoods, combined with supportive adults who encourage reading, can boost children’s literacy and learning opportunities, finds a new study by New York University Steinhardt School of Culture, Education, and Human Development.
By stretching the amount of time proteins can be simulated in their natural state of wiggling and gyrating, a team of researchers at Colorado State University has identified a critical protein structure that could serve as a molecular Achilles heel able to inhibit the replication of dengue virus and potentially other flaviviruses such as West Nile and Zika virus.
By treating living cells like tiny absorbent sponges, researchers have developed a potentially new way to introduce molecules and therapeutic genes into human cells.
Effect is greatest among those with highest illness burden
TAMPA, Fla. – Cancer patients are commonly treated with the maximum dose they are able to withstand that does not cause too many toxic side effects. However, many patients become resistant to these treatments and develop cancer recurrence. Researchers at Moffitt Cancer Center are using mathematical modeling based on evolutionary principles to show that adaptive drug treatments based on tumor responses to prior treatment are more effective than maximum-tolerated dose approaches for certain tumor situations.
Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered.
A new study reveals the geometric underpinnings of T-cell triggering through the precise engineering of T-cell receptor geometry in all three dimensions. The researchers used nanofabrication to create a biomimetic surface that simulates the key features of the APC, presenting T-cell receptor ligands in different geometric arrangements, with different inter-ligand spacings arranged in clusters of varying size. The results could have a significant impact on adoptive immunotherapy and the design of CAR T cells.
Some bacteria not only escape being killed by bacteria, they turn it into food. Until now, scientists have understood little about how bacteria manage to consume antibiotics safely, but new research from Washington University School of Medicine in St. Louis illuminates key steps in the process. The findings, published April 30 in Nature Chemical Biology, could lead to new ways to eliminate antibiotics from land and water, the researchers said. Environmental antibiotic contamination promotes drug resistance and undermines our ability to treat bacterial infections.
The majority of patients with diffuse large B cell lymphoma (DLBCL) can be treated effectively. However, people whose disease recurs face a shortage of good options, especially because the disease is driven by a complicated mix of genetic alterations. Genomic analysis by scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard now offers a better framework for understanding the disease’s many forms, which will help to predict individual patient outcomes and guide personalized treatment.
Breast cancer patients undergoing chemotherapy often experience severe and persistent tiredness. In a recent study, a team led by researchers from the National University of Singapore developed a novel approach to identify the onset of this common side effect and objectively follow its development.
Lonely consumers are capable of behaving morally, but aren’t motivated to, according to new research from Binghamton University, State University of New York.
Researchers have developed a new and improved version of an unconventional radio-astronomy imaging system known as a Phased Array Feed, which can survey vast swaths of the sky and generate multiple views of astronomical objects with unparalleled efficiency.
Georgia-based neurosurgeon will serve as 2018-2019 vice president
Latest News and Research from ACSM
A new study led by Johns Hopkins researchers adds to growing evidence that patients underuse nonopioid pain relievers to supplement opioid pain management after spine and joint surgery.
Identifying bottlenecks — i.e. places where birds concentrate on migration — helps bird conservationists know what areas to focus on and get the most bang for their buck, since a large percentage of a species’ population can pass through these small areas.
The more curious the child, the more likely he or she may be to perform better in school — regardless of economic background — suggests a new University of Michigan study.
Researchers at Intermountain Healthcare and University of Utah Health in Salt Lake City have completed a study identifying how community hospitals with fewer than 200 beds can develop antibiotic stewardship programs that work to prevent the growth of antibiotic-resistant organisms, or “superbugs,” which are becoming more common and deadly.
Heat pipes are devices to keep critical equipment from overheating. They transfer heat from one point to another through an evaporation-condensation process and are used in everything from cell phones and laptops to air conditioners and spacecraft.
While defects in a diamond are mostly undesirable, certain defects are a quantum physicist’s best friend, having the potential to store bits of information that could one day be used in a quantum computing system. Applied physicists at Cornell University have demonstrated a technique for engineering some of the key optical properties of those defects, providing a new tool for exploring quantum mechanics.
Climate models predict that an increase in greenhouse gases will dry out the Amazon rainforest in the future while causing wetter conditions in the woodlands of Africa and Indonesia. Researchers at the University of California, Irvine and other institutions have identified an unexpected but major factor in this worldwide precipitation shift: the direct response of the forests themselves to higher levels of carbon dioxide.
Hearing is an important part of fitness-for-duty assessments of police officers and other public safety professionals – but standard hearing tests don't give a true picture of whether these professionals can hear and communicate in the specific "noise environments" where they must work. A new approach to hearing assessment in public safety officers − which has been adopted by five government agencies in the United States and Canada − is presented in an article in Ear and Hearing. The official journal of the American Auditory Society, Ear and Hearing is published by Wolters Kluwer.
A paper by UAH physics professor Dr. Don Gregory and UAH Ph.D. student Seyed Sadreddin Mirshafieyan was recently published in "Nature, Scientific Reports."
Doctors could be a step closer to finding the most effective way to treat cancer with a double whammy of a virus combined with boosting the natural immune system, according to a pioneering study by researchers at The University of Texas Health Science Center at Houston (UTHealth) and The Ohio State University.
Dr. Matthew Niemiller, an assistant professor of ecology at UAH, conducts field research in caves throughout the Tennessee Valley and around the country to better understand species that are rare, threatened, endangered, or relatively unknown.
Spring 2018 Scholarship and Practice of Undergraduate Research seeks to provide evidence for undergraduate research's impact on student success in academe and beyond
Researchers at the University of Utah Health are looking to the salience network of the brain to develop music-based treatments to help alleviate anxiety in patients with dementia. Their research will appear in the April online issue of The Journal of Prevention of Alzheimer's Disease.
An alternative treatment option to the glucocorticoid-induced bone loss that can cause fractures now appears promising, according to an international study. Researchers compared the monoclonal antibody denosumab against a standard bisphosphonate treatment.
Latest News and Research from ACSM
Aquaporins are proteins that serve as water channels to regulate the flow of water across biological cell membranes. They also remove excess salt and impurities in the body, and it is this aspect that has led to much interest in recent years in how to mimic the biochemical processes of aquaporins potentially for water desalination systems.
Good cosmetic results are an important factor – but not the only factor – differentiating positive versus negative reviews for plastic surgeons on Google, Yelp, and other online review sites, according to a special topic paper in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Notre Dame researchers found that this communication varies across the colony and suggest that this bacterium may develop protective behaviors that contribute to its ability to tolerate some antibiotics.
Most studies evaluating platelet-rich plasma (PRP) injection for facial rejuvenation and other cosmetic procedures have reported positive results, according to a critical review in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Physician scientist Christopher Seymour talks about his experience treating sepsis patients and his new study indicating that quicker treatment improves survival odds.
Researchers from the Saint Louis University School of Medicine have discovered why many multiple myeloma patients experience severe pain when treated with the anticancer drug bortezomib. The study, which will be published April 27 in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing myeloma patients to successfully complete their treatment and relieving the pain of myeloma survivors.
Bone marrow biopsies are the gold standard for diagnosing and monitoring the progression of multiple myeloma, but these procedures are far too invasive to perform at every patient visit. Scientists from the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard, however, have shown that two ways to measure multiple myeloma DNA in blood samples provide highly detailed sets of genetic information that agree well not just with each other but with results from bone marrow tests.
A small number of scientists stand at the top of their fields, commanding the lion’s share of research funding, awards, citations, and prestigious academic appointments. Are they better and smarter than their peers—or did they luck out with early career success?
New research from the University of Adelaide has found that taking vitamin B6 could help people to recall their dreams.
Extensive data analyses show that supplemental oxygen, when given liberally to acutely ill adults, increases the risk of death without improving other health outcomes.
A team led by scientists at the Department of Energy’s SLAC National Accelerator Laboratory turned tiny liquid jets that carry samples into the path of an X-ray beam into thin, free-flowing sheets, 100 times thinner than any produced before. They’re so thin that X-rays pass through them unhindered, so images of the samples they carry come out clear.
A new analysis investigates the role of health concerns in climate litigation since 1990 and finds that although health is cited in a minority of cases, it may have critical potential for protecting communities from the effects of climate change and coal fired power plants.
In a review published today in the New England Journal of Medicine, Gregory R. Ciottone, MD, Director of the Division of Disaster Medicine in the Department of Emergency Medicine at BIDMC, advocates for an overhaul to the systems currently in place to respond to a chemical weapons strike on U.S. soil. In addition to calling for increased training and awareness, Ciottone also proposed a triage system – available online – based on recognizing the signs and symptoms of specific agents during the early phase of a chemical weapons attack.
Coral reef bleaching is stark evidence of the damage being inflicted by global climate change on marine ecosystems, but a research team led by scientists at the University of California, Irvine has found some cause for hope. While many corals are dying, others are showing resilience to increased sea surface temperatures, pointing to possible clues to the survival and recovery of these vitally important aquatic habitats.
In three landmark studies, Harvard researchers systematically profiled every cell in developing zebrafish and frog embryos to establish a roadmap revealing how one cell builds an entire organism—an unprecedented resource for the study of developmental biology and disease.
CU researchers mine data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers, showing genetic alterations, and "high mutation burden" that is an FDA-approved marker for immunotherapy.
The prevalence of U.S. children with autism spectrum disorder (ASD) is now 1 in 59, according to new estimates released Thursday by the Centers for Disease Control and Prevention (CDC), a significant increase from the 1 in 68 estimate in 2016.
In the fading afterglow of a supernova explosion, astronomers using NASA’s Hubble Space Telescope have photographed the first image of a surviving companion to a supernova. This is the most compelling evidence that some supernovas originate in double-star systems.
A group of researchers announced April 26 in Nature that they had managed to entangle perhaps the largest items yet, at a whopping 20 microns across—about the diameter of a single human hair.
This award will support Casey Greene's work on the Human Cell Atlas, a global effort to map every type of cell in the human body as a resource for investigating health and disease.
A University of Washington study finds that a community-based approach to substance-abuse prevention, which can include after-school activities, can affect young people into adulthood.
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