Hip replacement surgery not only improves quality of life but is also associated with increased life expectancy, compared to people of similar age and sex, reports a study in Clinical Orthopaedics and Related Research® (CORR®), a publication of The Association of Bone and Joint Surgeons®. The journal is published by Wolters Kluwer.
The CUORE experiment set the tightest limits yet on the rare decay of tellurium-130, providing insights into the nature of neutrinos.
Newly identified stem cells in the lung that multiply rapidly after a pulmonary injury may offer an opportunity for innovative future treatments that harness the body’s ability to regenerate. Scientists describe cells that could become a new tool to treat lung diseases across the lifespan, from premature infants to the elderly.
Researchers have identified a lung stem cell that repairs the organ’s gas exchange compartment. They isolated and characterized these progenitor cells from mouse and human lungs and demonstrated they are essential to repairing lung tissue damaged by severe influenza and other respiratory ailments.
Research led by St. Jude Children’s Research Hospital offers the most comprehensive analysis yet of the genomic alterations leading to cancer in children and affirms the need for pediatric-specific precision therapies
A UAB study shows that a gene therapy approach can help neurons remove lipofuscin, or cellular debris, in mouse models for frontotemporal dementia. The study added a gene that encodes for the missing protein progranulin.
Engineers from the University of Maryland created a non-flammable battery from ceramic materials by using a 'melty' layer that, when cool, unites a solid-state battery.
The breakthrough may expand research on the roles of glycans in human diseases, including cancers.
A new Medicare records study by Johns Hopkins researchers has added to mounting evidence that a common surgery designed to remove damaged, worn ends of the thin rubbery cartilage in the knee joint brings little or no benefit to people over the age of 65.
A new study finds that muscle fibers in Duchenne muscular dystrophy (DMD) split during regeneration to such an extreme that the muscle is weakened beyond repair. The article is published ahead of print in the American Journal of Physiology—Cell Physiology.
In a national medical records analysis, researchers at Johns Hopkins Medicine say there is evidence that the number of gender affirming surgeries performed in hospitals for transgender individuals is on the rise, along with increased access made possible by Medicare, Medicaid or private insurance coverage for the procedures.
Although obesity has been considered a risk factor for more-severe cases of the flu, a new study found that it is not a risk factor for severe acute respiratory illnesses, including the flu, in children or adults.
Tracking nearly 8,000 girls from adolescence through their late 20s – far longer than other studies have – a Cornell University researcher says girls who get their periods earlier than peers are likely to experience depression and antisocial behavior well into adulthood. The study, “Age at Menarche, Depression and Antisocial Behavior in Adulthood,” was published Dec. 26, 2017, in Pediatrics.
A tiny snail could be a big help to researchers measuring water quality along the U.S. and Canadian Atlantic coast.
To address embarrassing, inconvenient and costly male fertility testing, researchers from FAU are developing a home-based kit that accurately, quantitatively, and quickly, provides a complete semen evaluation using microfluidics, an app and a smartphone. After all, if women can use pregnancy tests in the comfort and privacy of their own homes, men also should be able to test their semen at home without any hassles.
Six years into Lebanon’s refugee crisis, St. Jude Children’s Research Hospital and the Children’s Cancer Center of Lebanon at the American University of Beirut Medical Center offer a blueprint for effective childhood cancer treatment during turmoil
Researchers at The Ohio State University report that they’ve figured out the mechanism by which the CRISPR gene-editing enzyme Cas9 determines where and when to cut DNA strands—a discovery that could help prevent gene-cutting errors.
Patients who were treated for breast cancer or lymphoma are more than three times at risk for developing congestive heart failure, compared with patients who did not have cancer. Congestive heart failure is when the heart muscle does not pump blood as well as it should. This research is being presented at the American College of Cardiology’s 67th Annual Scientific Session.
Scientists have discovered a novel chemical state, first proposed about 90 years ago, that enables a high-performance, low-cost sodium-ion battery. The battery could quickly and efficiently store and distribute energy produced by solar panels and wind turbines across the electrical grid.
A study in the Journal of Neuroscience reveals that activation of a pregnant mother’s immune system can affect her baby’s brain development. Researchers at CHLA, found that short- and long-term brain functioning can be influenced by immune system activity during the third trimester of gestation.
Our bodies are not just passively growing older
Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released today that are anticipated to improve survival and decrease kidney complications.
New teaching standards like the Next Generation Science Standards call for weaving science, technology, engineering and math (STEM) into classrooms better. What makes this integration effective?
Scientists at PPPL have discovered key conditions that give rise to fast magnetic reconnection, the process that triggers solar flares, auroras, and geomagnetic storms that can disrupt signal transmissions and other electrical activities, including cell phone service.
Researchers from Argonne and Harvard University built a metasurface-based lens atop a Micro-Electro-Mechanical System (MEMS) platform. The result is a new, infrared light-focusing system that combines the best features of both technologies while reducing the size of the optical system.
Writing in the February 27 online issue of Science Signaling, researchers at University of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and metastasis.
When women take the common diabetes medication metformin during pregnancy, it may put their children at increased risk of having obesity or overweight.
The average rate at which Americans tip for services has been increasing steadily for decades, but the practice has been branded over the years as classist, anti-egalitarian, and downright undemocratic, leading some restaurateurs to abandon it. A new paper, drawing insight from nonlinear dynamics and published in the journal Chaos, hopes to shed light on the economically irrational world of tipping, showing that at a certain point, banning the practice might be fair and profitable.
Athletes who suffer life-threatening heat stroke should be cooled on site before they are taken to the hospital, according to an expert panel's report published in the journal Prehospital Emergency Care. The principle of "cool first, transport second" differs from the usual practice of calling 911 and getting to the hospital as soon as possible.
Racial discrimination can have serious health consequences. A new study led by the University of California, Irvine has found that more self-reported incidents among black and Latino adults corresponded to higher blood pressure levels, putting these populations at greater risk for cardiovascular disease.
About 3 out of 4 Americans agree that smoking cigarettes causes health problems, but public perception of the risks posed by smoking may be declining, according to a Duke Health study published in the journal Drug and Alcohol Dependence.
The largest and oldest Chinook salmon — fish also known as "kings" and prized for their exceptional size — have mostly disappeared along the West Coast, according to a University of Washington-led study.
The rural physician shortage is well-established, and there's the notion that doctors don't necessarily establish their practices where need for health care is greatest––in poor and unhealthy communities
SBP researchers have developed the first ever high-throughput, genome-scale imaging-based approach to investigate protein stability. The method has been used to identify several previously unknown human proteins that HIV degrades to enhance its infection process.
The United States could reliably meet about 80 percent of its electricity demand with solar and wind power generation, according to scientists at the University of California, Irvine; the California Institute of Technology; and the Carnegie Institution for Science.
A new study from Indiana University suggests that a compound previously tested to treat osteoarthritis pain appears to block neuropathic pain and decrease signs of opioid dependence.
A new study involving Iowa State University scientists explores how birds in the Mariana Islands help to disperse the seeds of a wild chili plant. The research highlights the unique ways different species help one another, a concept known as mutualism.
AMP has published consensus, evidence-based recommendations to aid clinical laboratory professionals when designing and validating clinical CYP2C19 assays, promote standardization of testing across different laboratories and complement existing clinical guidelines.
慢性疾病患者往往会对在临床试验中显示早期积极效果的治疗抱有希望。 然而，Mayo Clinic领导的一项发表在Mayo Clinic Proceedings上的新研究报告说，可能有三分之一以上的早期临床试验结果都会被严重夸大。
For years, researchers have attempted to harness the full potential of gene therapy, a technique that inserts genes into a patient’s cells to treat cancer and other diseases. However, inserting engineered DNA molecules into cells is difficult. A team of engineers at Washington University in St. Louis has developed a new method that could make the process easier.
Psychedelic mushrooms likely developed their “magical” properties to trip up fungi-munching insects, suggests new research. The work helps explain a biological mystery and could open scientific doors to studies of novel treatments for neurological disease.
Emerging adulthood (between ages 18-25) is a period of critical vulnerability for problematic alcohol use. A substantial amount of research has examined alcohol risks in college-student populations, while much less research has focused on emerging adults who are not attending college. This study investigated the effectiveness of a brief personalized feedback intervention (PFI) tailored for nonstudent at-risk drinkers, the influence of gender on intervention outcomes, and the acceptability of the intervention to participants.
Blood plasma samples from a mouse that received the Angptl3 CRISPR treatment (right) and a mouse that was untreated (left). The cloudiness of the sample on the left is from the high content of cholesterol and triglycerides.
Still’s disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen.
Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of new research suggesting that, on average, most women were willing to accept the risk of unnecessary follow-ups for an increased chance of detecting a cancer in screening.
States with robust tobacco control policies and regulations, such as smoke free air laws and taxes on cigarettes, not only have fewer cigarette users but also fewer e-cigarette users, according to research from NYU School of Medicine and the NYU College of Global Public Health.
The escalating influence of modern biomedical conceptions of health and illness now dominate healthcare delivery. A new study finds that this expanding “medical industrial complex” is not straightforwardly responsible for improved life expectancy and mortality in first-world nations.
Does the signature size match the personality?According to Chad Ham, assistant professor of accounting at Washington University in St. Louis' Olin Business School, a chief financial officer (CFO) with an oversized signature is more likely to make questionable choices due to an oversized ego. According to a paper published in the December edition of the Journal of Accounting Research, "narcissistic CFOs are less likely to recognize losses in a timely manner... consistent with a willingness to cover up past mistakes."
A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing mutations and could enable researchers to discover new uses for existing drug treatments.
Critically ill patients who experience long periods of hypoxic, septic or sedative-associated delirium, or a combination of the three, during an intensive care unit (ICU) stay are more likely to have long-term cognitive impairment one year after discharge from the hospital, according to a new study.
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