The researchers found that participants of a multicenter prospective cohort who had central sleep apnea or central sleep apnea with Cheyne-Strokes respiration, both caused by abnormal respiratory signals from the brain, were at greater risk of developing AF compared to those without central sleep-disordered breathing. The risk increased with age
Some of the same gene mutations that cause heart defects in children also lead to neurodevelopmental delays, including learning disabilities. New research may later enable clinicians to identify and treat infant heart patients at higher risk for neurodevelopmental problems.
Children with allergic disease, particularly asthma and hay fever, have about twice the rate of high blood pressure and high cholesterol, setting them on a course for heart disease at a surprisingly early age, reports a new Northwestern Medicine study.
The Society of Thoracic Surgeons has released new clinical practice guidelines that recommend expanding the use of arteries from the chest and forearm rather than using veins from the leg when performing coronary artery bypass grafting (CABG) surgery in certain patients
Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It’s a discovery that could provide treatment options for cardiovascular disease — one of the leading causes of death in Canada.
A new study published in PLOS ONE found that the Transcendental Meditation technique and lifestyle changes both appear to stimulate genes that produce telomerase, an enzyme that's associated with reduced blood pressure, cardiovascular disease, and mortality.
It’s called optogenetics and it refers to the use of light to regulate cells. In this case, NIBIB-funded researchers engineered fruit flies that carry light-sensitive proteins in their hearts. When hit by a blue laser, the proteins open channels that cause a flow of ions or charged particles that cause the heart to beat.
Babies born with heart problems have a number of genetic changes in common, even when there is no family history of heart disease, scientists have found.
Dr. Packer is the principal investigator of a trial published in the New England Journal of Medicine (NEJM) Dec. 3 issue, showing new evidence about a major breakthrough in the medication management and treatment of heart failure patients. The updated study information and analysis builds upon the team’s earlier research about Angiotensin Receptor Neprilysin inhibitor (ARNi) category of drugs.
People who have a higher sense of purpose in life are at lower risk of death and cardiovascular disease, reports a pooled data analysis in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
With the support of a $2.8 million NIH grant, scientists at The Scripps Research Institute will explore mutations in the nuclear lamina—the outer edge of the cell nucleus— which have been linked to many diseases, from muscular dystrophies and heart disorders to type 2 diabetes and premature aging.
The Cardiovascular Research Foundation (CRF) is pleased to announce that Michael O’Riordan joins the organization today as Senior Editorial Journalist for TCTMD, the leading online resource for cutting-edge news and information in interventional cardiovascular medicine.
The first full outcomes report from the STS/ACC TVT Registry provides an overview of trends and analyzes outcomes of patients having TAVR procedures. The report also describes the future of the TVT Registry.
Researchers at the University at Buffalo are studying whether plant sterols can be used as a natural alternative to drug therapy for pregnant women who have high cholesterol.
Endurance exercise accelerates the development of heart problems in individuals with a particular genetic mutation, a new study finds. In mice with a mutated version of desmoplakin, a protein that maintains the heart wall, exercise made the heart walls come apart sooner. The findings offer insight into how to best manage exercise in individuals with the mutation.
The Cardiovascular Research Foundation (CRF) has joined #GivingTuesday, a global day of giving that harnesses the collective power of individuals, communities and organizations to encourage philanthropy and to celebrate generosity worldwide. This year 100% of the donations to CRF made on Giving Tuesday will go directly to the CRF Fellows Fund, which was established to mentor the next generation of cardiovascular researchers and provide financial support for the rapid advancement of breakthrough treatments needed in the fight against heart disease, the #1 killer of men and women worldwide.
For 17 consecutive years Mount Sinai awarded highest "two-star" rating by New York State Department of Health for percutaneous coronary interventions.
University Hospitals physicians implanting Boston Scientific EMBLEM™ Subcutaneous Implantable Cardioverter-Defibrillator (S-ICD) System in patients who had survived a sudden cardiac arrest (SCA).
In one of the first studies of its kind, Tufts researchers show that even among Americans in their mid-70’s and older, being more active, including walking at a reasonable pace or distance, is linked to a lower risk of cardiovascular events.
A discovery about how the body deals with the cholesterol contained within its dying cells has suggested an exciting new approach to control people’s cholesterol levels – and thus their risk of developing heart disease.
Her findings over the last year suggest that the introduction of male sex chromosomes in biological females could raise the risk of aneurysm. She says this work may have a broader impact, specifically surrounding issues of gender identity.
Monday mornings could be harmful to your health. Even routine sleep changes such as waking up early for work during the week may raise the risk of developing metabolic problems such as diabetes and heart disease, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
The increasing use of testosterone replacement therapy to treat reduced testosterone level in older men has been accompanied by growing concerns over its long-term safety. Two studies examining the health risks of receiving testosterone will be presented at Cardiovascular, Renal and Metabolic Diseases: Physiology and Gender conference, supporting opposite conclusions regarding risks.
Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between higher levels of a specific kind of air pollution in major urban areas and an increase in cardiovascular-related hospitalizations such as for heart attacks in people 65 and older.
Donald Rabren came in to have open-heart surgery until a surgeon discovered great risk in continuing and elected to close him up and do a different procedure three days later.
Newborns with a congenital heart defect often need advanced medical care to survive, leaving them vulnerable to cognitive delays. Various factors contribute to these delays. But what role does proper growth and feeding mode at the beginning of life play? A research team – led Penn Nursing – found that newborns (up to three months) with poor growth and CHD, who required device-assisted feeding, were at an increased risk for neurodevelopmental delays at six and twelve months.
• Higher levels of urinary potassium excretion, which closely correlate with intake amounts, were linked with a slower decline of kidney function and a lower incidence of cardiovascular complications among patients with type 2 diabetes and normal kidney function.
Linking digital activity trackers to smartphones and periodically pinging users with personalized texts that urge them to walk more can significantly increase physical activity levels and spark healthy behavior changes, according to findings of a pilot study conducted at Johns Hopkins.
Chest pain in female-pattern heart disease is linked with abnormal heart blood flow, demonstrated with a drug commonly used to alleviate chest pain patients with coronary artery disease, which was found to be ineffective in patients with moderate female-pattern heart disease, but may offer some relief for sicker patients, a new Cedars-Sinai Heart Institute study shows. The study’s results were presented today as a late-breaking trial at the American Heart Association Scientific Sessions in Orlando.
Bleeding complications present the most common risk for patients taking blood thinners. Without an antidote, there is no way to quickly reverse the effects of a blood thinner in emergency situations.
94-year-old Wade Gladden came to UAB with only 20 percent heart function, but physicians put a monthslong plan in place to restore function — and the Alabama resident hit every mark along the way.
Bypass patients who are older, female and/or from lower-income neighbourhoods are more likely to face delays in beginning cardiac rehabilitation (CR), making them less likely to complete CR, which can lead to a higher mortality risk, suggests a new study.
Treating patients 50 and older with high blood pressure to a systolic blood pressure of less than 120 mm Hg reduced rates of cardiovascular events, including heart attack, heart failure and stroke, by 25 percent.
Heart patients who had undergone an angioplasty procedure that opened only some blocked arteries tended to have a resolution of their chest pain, making it unnecessary to add another medication to treat the symptom, according to a study led by the Duke Clinical Research Institute.
Cardiovascular disease risk in women increases after menopause and is associated with the drop in estrogen levels. Menopausal hormone therapy could slow the progression, but oral formulations also increase the risk of blood clots. A new study reports that whether a woman will obtain cardiovascular benefits from certain types of hormone therapy may depend on her genes.
Continuous chest compression, touted as the new way to perform cardiopulmonary resuscitation, was not an improvement over standard CPR, according to findings published in NEJM by eight US and Canadian universities in the ROC consortium.
People with high fitness levels in midlife have significantly lower annual health care costs after age 65 than people with low fitness in midlife, after adjusting for cardiovascular risk factors, according to a study published in the Journal of the American College of Cardiology (JACC).
New research shows that drinking one 16-ounce energy drink can increase blood pressure and stress hormone responses significantly. This raises the concern that these response changes could increase the risk of cardiovascular events.
A group of researchers led by Mayo Clinic has discovered that disclosing genetic risk for coronary heart disease (CHD) results in lower low-density lipoprotein cholesterol (LDL), also known as bad cholesterol.
The number of angioplasty procedures classified as rarely appropriate declined sharply between 2010 and 2014, as did the number of those performed on patients with non-acute conditions, according to a study published today in the Journal of the American Medical Association and simultaneously presented at a meeting of the American Heart Association in Orlando.
Heart failure patients with preserved ejection fraction (HFpEF) — where the heart becomes stiff and cannot relax or fill properly — did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo.
A lack of vitamin D can result in weak bones. Recent studies also show that vitamin D deficiency is linked to more serious health risks such as coronary artery disease, heart attacks, and strokes.
Patients whose blood pressures spikes in the doctor’s office but not at home, and patients whose blood pressure spikes at home but not in the doctor’s office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.
A new study finds that at least 16.8 million Americans could potentially benefit from lowering their systolic blood pressure (SBP) to 120 mmHg, much lower than current guidelines of 140 or 150 mmHg. The collaborative investigation between the University of Utah, University of Alabama at Birmingham, and Columbia University, will be published Nov. 9 online in the Journal of the American College of Cardiology (JACC). The scientists calculated the potential impact of preliminary results from the Systolic Blood Pressure Intervention Trial (SPRINT) to be presented in full at the American Heart Association meeting and published online in the New England Journal of Medicine, also on Nov. 9.
Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.
A new study of generally healthy men who used testosterone replacement therapy to normalize testosterone levels has found that taking supplemental testosterone does not increase their risk of experiencing a heart attack or stroke.
Patients whose blood pressure target was lowered by medications to reach a systolic goal of 120 mmHg had their risk for heart attack and heart failure reduced by 38 percent, and their risk for death lowered by 27 percent. Aggressive treatment appeared to be as effective for adults age 75 and older as for adults age 50-74, according to results from the Systolic Blood Pressure Intervention Trial (SPRINT) presented at the American Heart Association meeting and published online in the New England Journal of Medicine (NEJM) on Nov. 9, 2015.
A team of researchers from the Cardiothoracic Surgical Trials Network (CTSN) found that recipients of a mitral valve replacement for Ischemic mitral regurgitation (IMR) experienced a lower rate of heart failure and fewer cardiovascular-related hospital readmissions in the two years following surgery.
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