Feature Channels: Aging

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Investigadores y colaboradores de Mayo Clinic han descubierto hallazgos clínicos clave que pueden ayudar a los médicos clínicos a reconocer causas que podrían tratar la demencia rápidamente progresiva en pacientes que, de lo contrario, podrían recibir un diagnóstico de enfermedad de Creutzfeldt-Jakob. Su estudio se publicó en la versión en línea de Neurology Clinical Practice, la revista médica oficial de la Academia Americana de Neurología.

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Slipping on ice or tripping over a curb can result in broken bones or more serious injuries. To avoid taking an unexpected tumble, it’s important to be aware of your surroundings and watch where you’re walking, a UT Southwestern Medical Center orthopedist advises.

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Os pesquisadores e colaboradores da Mayo Clinic identificaram achados clínicos importantes que podem ajudar os médicos a reconhecer pacientes com causas potencialmente tratáveis de demência rapidamente progressiva e que seriam diagnosticados erroneamente com a doença de Creutzfeldt-Jakob. O estudo foi publicado on-line na Neurology Clinical Practice, uma revista médica oficial da American Academy of Neurology.

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The American Macular Degeneration Foundation will be hosting multiple, awareness-spreading activities throughout February, which is AMD Awareness Month, including new films on living well with AMD.

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Rutgers Biomedical and Health Sciences (RBHS) is launching the Herbert and Jacqueline Krieger Klein Alzheimer’s and Dementia Clinical Research and Treatment Center. Based at the Rutgers Brain Health Institute and scheduled to open in fall 2023, the center will offer research expertise from the institute, Rutgers Robert Wood Johnson Medical School, Rutgers New Jersey Medical School and the Rutgers Institute for Health, Health Care Policy and Aging Research as well as facilitate clinical research in Alzheimer’s disease that could result in new medical treatments.

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The study analyzed data from 1,445 participants aged 45 to 85 years from the Canadian Longitudinal Study on Aging. The participants provided blood samples for DNA methylation analysis and completed a self-report questionnaire on ACEs. These experiences include childhood exposure to physical, emotional or sexual abuse, neglect, as well as exposure to parental intimate partner violence or poor parental mental health. The data was analyzed to determine if there was an association between early childhood adversity and accelerated biological aging.

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A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

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KINGSTON, R.I. – Jan. 31, 2023 – China’s National Bureau of Statistics recently released data showing the country’s first population decline in decades. At the end of 2022, the population of mainland China stood at 1.411 billion people, down 850,000 from the previous year.Around the world, experts called it a tipping point for a nation looking to continue an era of rapid economic expansion and boost its falling birth rate.

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ESTIMADA MAYO CLINIC: Tenho pouco mais de 50 anos e adoro meu estilo de vida ativo. Recentemente, ouvi relatos sobre o aumento de torções e fraturas no tornozelo, particularmente em uma população mais velha, devido em parte à atividade e ao envelhecimento. Em primeiro lugar, como posso evitar essas lesões?

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Tengo poco más de 50 años y disfruto de un estilo de vida activo. Hace poco, me enteré de que hay informes sobre un aumento de esguinces y fracturas de tobillo, particularmente entre la población más adulta, debido a una combinación de dos factores: la actividad y la edad. ¿Cómo puedo evitar estas lesiones en primer lugar?

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Age-based heuristics can lead to large differences in breast cancer treatment based on small differences in chronologic age, according to a new analysis of more than 500,000 patient records. Patients aged 70 were nearly twice as likely to be passed over for standard-of-care radiation as those aged 69. There were no similar gaps between other age pairs. The study is among the first to demonstrate an age cutoff heuristic in oncology.

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The typical person living with arthritis in the UK is 20% less likely to be in work than their equivalent without the condition, new research shows.

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Whether you call them comfort foods, highly processed foods, junk foods, empty calories or just some of Americans’ favorite foods and drinks, about 13% of Americans aged 50 to 80 have an unhealthy relationship with them.

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Below are some of the latest articles that have been added to the Behavioral Science channel on Newswise, a free source for journalists.

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UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.

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The Vanderbilt Memory and Alzheimer’s Center is recruiting individuals age 50 and older to participate in a study researching early drivers of Alzheimer’s disease.

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Thai Red Cross Emerging Infectious Diseases Health Science Center, Faculty of Medicine, Chulalongkorn University has researched a blood test for markers of Alzheimer’s that can give a 10-year warning, so people can be prepared to slow down the development of dementia in old age.

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The American Society of Nephrology (ASN) is encouraged by the recent U.S. Preventive Services Task Force (USPSTF) announcement to solicit comment on USPSTF’s draft research plan on screening for kidney diseases. This development follows more than a decade of advocacy in support of more kidney health screening by ASN and other stakeholders dedicated to intervening earlier to slow or stop the progression of kidney diseases.

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The sport of orienteering, which draws on athleticism, navigational skills and memory, could be useful as an intervention or preventive measure to fight cognitive decline related to dementia, according to new research from McMaster University.

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La menopausia, que es el fin de los ciclos menstruales, puede provocar síntomas como sofocos, sudoración nocturna, insomnio y cambios en el estado de ánimo. Las mujeres no tienen por qué sufrir en silencio. La Dra. Jewel Kling, presidenta de la División de Salud de la Mujer de Mayo Clinic en Scottsdale, Arizona, explica las terapias hormonales y no hormonales.

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A menopausa (o fim dos ciclos menstruais) pode produzir sintomas como ondas de calor, transpiração noturna, insônia e mudanças de humor. As mulheres não precisam sofrer em silêncio. Muitas opções de tratamento estão disponíveis. A Dra. Jewel Kling, diretora da divisão de Saúde da Mulher na Mayo Clinic em Scottsdale, Arizona, fala sobre terapias hormonais e não hormonais.

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Menopause, the end of menstrual cycles, can produce symptoms such as hot flashes, night sweats, insomnia and mood changes. Women do not need to suffer in silence: Many treatment options are available. Jewel Kling, M.D., chair of the Division of Women’s Health at Mayo Clinic in Scottsdale, Arizona, describes hormonal and nonhormonal therapies.

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High blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decrease as people age. The study is published in the January 18, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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COVID-19 interrupted or delayed medical treatment for many people who chose to put off elective procedures or couldn't get in to see a specialist.

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Aging and related diseases are associated with alterations in oxidative status and low-grade inflammation, as well as a decreased endoplasmic reticulum (ER) unfolded protein response (UPR). UPR is a functional mechanism by which cells attempt to protect themselves against ER stress. Researchers analyzed these proteins in peripheral blood mononuclear cells of elderly subjects and used computer simulation to predict the key proteins associated with these biomolecules underlying physiological adaptations to exercise. They collected blood samples about five to six days before and after the training period and analyzed various oxidative stress biomarkers in peripheral blood mononuclear cells. The study takes research one step further in helping to elucidate the benefits of exercise in this population.

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Negative emotions, anxiety and depression are thought to promote the onset of neurodegenerative diseases and dementia. But what is their impact on the brain and can their deleterious effects be limited?

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The U.S. Food and Drug Administration (FDA) recently granted approval to Lecanemab, the first Alzheimer’s disease treatment to win approval since the largely failed rollout of Aduhelm two years ago.

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Speed or strength, which is more important?” may be a critical question for not only athletes but also knee surgery patients.

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Vision impairment disproportionately impacts older adults

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Maintaining a healthy weight during the golden years is a priority for many older adults. While previous research has shown that cutting calories can lower disease risk factors, it's unclear whether it can have a long-term positive impact on disease and disability. With a $2.1 million grant from the National Institutes of Health, researchers at Wake Forest University School of Medicine will evaluate the potential benefits of diet interventions such as time-restricted eating and caloric restriction.

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In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

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From a cranky-faced fetus scowling at her mother’s healthy lunch choice to an octogenarian still benefiting from long-ago musical lessons, the most impactful psychological science research published in 2022 reveals that new understandings of human behavior—studied across the lifespan and from within a remarkable diversity of topics and scientific subdisciplines—continue to resonate with wide audiences.

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Findings highlight potential benefit of hearing aid use

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In a study using data from nearly 1,200 older adults, Johns Hopkins Medicine researchers have added to a growing body of evidence that loss of the sense of smell is a predictive marker for an increased risk of frailty as people age.

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Early retirement can accelerate cognitive decline among the elderly, according to research conducted by faculty at Binghamton University, State University of New York.

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UC San Diego School of Medicine study shows cannabis-related emergency department visits among older adults are on the rise with high risk for adverse effects of cannabis use for ages 65 and older.

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Findings from a UC Davis Comprehensive Cancer Center study prompt researchers to question current cervical cancer screening guidelines for older women.

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Two separate eye diseases may contribute to age-related macular degeneration (AMD), a leading cause of blindness in the United States, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.