In this randomized clinical trial, anakinra did not prevent the need for mechanical ventilation or reduce mortality risk compared with standard of care alone among hospitalized patients with severe COVID-19 pneumonia. Future research should assess anakinra in patients with less severe pneumonia.
This national-level analysis found substantial adverse maternal outcomes among pregnant patients with COVID-19 infection at delivery during the early pandemic in the U.S. Specifically, the odds of severe respiratory complications were increased among pregnant patients with COVID-19 infection at delivery.
A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent. Their discovery could lead to more potent vaccines and new antibody-based treatments.
After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.
The U.S. experienced an unprecedented number of group A streptococcal infections in children from October to December of 2022, which should alert physicians to check for the potentially deadly infectious disease as the country moves out of the pandemic, according to research published by UTHealth Houston.
The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.
A group of physicians and scientists with the University of Miami Miller School of Medicine are releasing an important study that will be published in the journal Pediatrics on Thursday, showing that COVID-19 can cross into the placenta of pregnant women and cause brain injury in newborns, as evidenced with 2 cases they treated here in Miami. One of the infants also died at about 13 months old. Further testing of the infant’s brain specimen showed that the virus was still present in the brain at the time of death—which was over a year after birth.
Researchers have shown that, in two cases, COVID-19 infection breached the placenta and caused brain damage in the newborn.
Cleveland Clinic researchers found 41% of patients with long COVID, had moderate to severe sleep disturbances. The retrospective analysis also identified risk factors for moderate to severe sleep disturbances, including race, hospitalization for COVID-19, greater anxiety severity and fatigue. After adjusting for demographics, Black patients were three times more likely to develop these sleep disturbances. The findings were published in Journal of General Internal Medicine.
Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs. Increasingly, scientists are learning that organ dysfunction results from damage to the blood vessels, but why the virus causes this damage is unclear.
In a twist on the question, “Which came first, the chicken or the egg?”, scientists have long faced a similar question about how human adenovirus replicates: “Which comes first, assembly of the viral particle, or packaging of the viral genome?” Now, in a new study published today in Nature, researchers at Children’s Hospital of Philadelphia (CHOP) have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.
Recent study reveals neurodegenerative biomarkers after COVID-19, gives clues for monitoring and potential treatment of long COVID
The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies.
The saliva of mosquitoes infected with dengue viruses contains a substance that thwarts the human immune system and makes it easier for people to become infected with these potentially deadly viruses, new research reveals.
Getting sick often may impact how quickly the brain ages and increase the risk of dementia or other forms of cognitive decline.
A study by researchers at Washington University School of Medicine in St. Louis shows that vaccinating people with updated boosters as new variants of the virus that cause COVID-19 emerge could shore up population immunity even as the virus mutates, and thereby prevent another deadly COVID-19 wave.
The National Institute of Allergy and Infectious Diseases has awarded a five-year, $15.45 million grant to the San Diego Center for AIDS Research at UC San Diego, renewing support that extends back to an original establishing grant in 1994 at the height of the AIDS epidemic.
Forty per cent of people diagnosed with HIV in Aotearoa between 2011 and 2020 were diagnosed late, a University of Otago study shows.
New research led by Penn State reveals that the stem region of the spike protein became progressively tighter over time, and the team thinks this likely improved the virus’s ability to transmit through nasal droplets and infect host cells once in the body.
In a study among residents of Ventura County, California, rates of sudden cardiac arrest rose sharply during the COVID-19 pandemic.
More than half of patients who suffer from chronic hepatitis B have the e antigen (HBeAg)-negative form of the disease. Even after many years of antiviral treatment with nucleos(t)ide analogues (NUC), lasting immune control is almost never seen.
A new study led by Worcester Polytechnic Institute (WPI) brings into sharper focus the structural details of the COVID-19 virus, revealing an elliptical shape that “breathes,” or changes shape, as it moves in the body.
Given the recent news regarding tickborne illnesses, Cummings School of Veterinary Medicine recently posed a question about a mild winter and if that would result in an increase of ticks in the spring. A pair of Cummings School experts shared their advice.
New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.
In a new study, researchers analyzed data from Cali, Colombia, to develop a model that provides a template for tracking data, predicting transmission, and informing health surveillance systems.
Research by the Milner Centre for Evolution at the University of Bath, UK, along with colleagues at Universities of Oxford and Aberdeen, finds that trust in scientists has hugely increased overall since the COVID-19 pandemic, but that attitudes have also become more polarized. The study also found that people were more likely to take the COVID-19 vaccine if their trust in the science had increased.
Researchers found that, despite being heavily immunocompromised, haematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.
The seasonal flu vaccine is less effective in some years than others. New St. Jude research showed one reason behind this lack of efficacy is the inclusion of flu strains with an unstable viral protein.
The COVID-19 pandemic posed an immense challenge on the health care industry in 2020 and 2021. While hospitals were inundated with COVID-19 cases, other illnesses such as respiratory syncytial virus (RSV) saw a decrease in hospital visits, particularly in the fourth quarter of 2020 and the first quarter of 2021.
There are no vaccines or therapies available for lymphocytic choriomeningitis virus (LCMV) infection. This pathogen spreads easily and is extremely common in people worldwide.
From septic shock to sticker shock. Keep up with this ever-growing, changing sector. Below are some of the latest stories on healthcare on Newswise.
Researchers have designed a molecule that slows the effects of one of SARS-CoV-2's more dangerous components – an enzyme called a protease that cuts off the immune system's communications and helps the virus replicate. While much more needs to happen to develop a drug, scientists can begin to imagine what that drug could look like – thanks to new images of the molecule bound to the protease.
Wistar Institute researchers identified hopeaphenol, a natural plant-based compound, as possessing antiviral properties that are effective against HIV.
Countries must intensify efforts to track HIV and hepatitis C virus (HCV) incidence among people who inject drugs, and to prioritise this group in prevention and elimination work, according to new University of Bristol-led research, published online in The Lancet Gastroenterology & Hepatology.
Scientists report using a single-atom-thick nanomaterial to build a device that can simultaneously detect the presence of the viruses that cause COVID-19 and the flu — at much lower levels and much more quickly than conventional tests for either. They will present their results at ACS Spring 2023.
While COVID-19 can be transmitted via contact with contaminated objects, most studies have focused on airborne droplet transmission.
A quick, affordable diagnostic test developed by a Washington State University researcher may help curb one of the most prevalent but least discussed sexually transmitted infections.
You might have heard or read about the ‘superbug’ Candida auris (C. auris), but is it as scary as the news makes it seem?
A new study identified a compound that prevents C. diff infection. Researchers are now using this compound to develop new drug candidates that might eventually offer a way to prevent serious C. diff infections.
New research from Boston Medical Center found that substance use disorders do not increase the likelihood of dying from COVID-19. Published in Substance Abuse: Research and Treatment, the study showed that the increased risk for severe COVID-19 in people with SUD that has been seen may be the result of co-occurring medical conditions.
Heated tobacco products—an alternative to traditional cigarettes, similar to e-cigarettes or vapes—do not burn tobacco leaves, but rather allow users to inhale the vapor produced by heating the tobacco leaves.
Researchers have developed a molecule that is, when administered nasally, extremely effective in preventing the disease caused by all known variants of the SARS-CoV-2 virus.
For mosquito-borne diseases such as dengue fever, the abundance of the insects in places where people gather has long served as the main barometer for infection risk. A new study, however, suggests that the number of “hidden” infections tied to a place, or cases of infected people who show no symptoms, is the key indicator for dengue risk.
The Centers for Disease Control and Prevention issued an alert that infections from the fungus Candida auris are increasing. Theresa O’Meara, Ph.D., an assistant professor in the Department of Microbiology & Immunology at the U-M Medical School, speaks about the emerging threat.
People infected with SARS-CoV-2, the virus that causes COVID-19, may experience genome structure changes that not only may explain our immunological symptoms after infection, but also potentially link to long COVID, according to a new study by researchers at UTHealth Houston.
Rutgers New Jersey Medical School will receive $20 million over five years from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to coordinate research being conducted in eight nations on tuberculosis (TB) control and prevention.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
