Curated News: JAMA

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10-Mar-2022 3:05 PM EST
People Who Die by Suicide With a Firearm Are Less Likely to Have Sought Treatment
Rutgers University-New Brunswick

People who kill themselves with a firearm are more likely to talk about suicide a month before ending their lives than ask for help and seek mental health treatment, according to a study by the New Jersey Gun Violence Center at Rutgers University.

Released: 10-Mar-2022 12:15 PM EST
Moffitt Study Finds Cancer Patients Do Benefit From COVID-19 Vaccination
Moffitt Cancer Center

The study, led by Moffitt Cancer Center, followed 515 patients with varying cancers. The goal was to evaluate if patients had an immune response to the Moderna mRNA-1273 vaccine and if that response differed by diagnosis and treatment.

Released: 10-Mar-2022 6:05 AM EST
New Mesothelioma Drugs, Once Hailed as Gamechangers, Don’t Live Up to the Hype
Sbarro Health Research Organization (SHRO)

Malignant Pleural Mesothelioma (MPM) is an aggressive cancer mostly related to asbestos exposure whose incidence is constantly rising, especially in low-income countries.

Released: 9-Mar-2022 8:05 AM EST
Even at best hospitals, low-income older cancer patients struggle after surgery
Michigan Medicine - University of Michigan

They’re old enough to qualify for Medicare, and their incomes are low enough to qualify them for Medicaid. And when they have surgery to remove a cancerous tumor, a new study finds, they suffer more complications and incur higher costs than patients with Medicare alone, even at top hospitals.

Newswise: Self-Administered Screening Can Provide Benefits
for Patients and Providers
4-Mar-2022 3:05 PM EST
Self-Administered Screening Can Provide Benefits for Patients and Providers
Atrium Health Wake Forest Baptist

Have you ever felt uncomfortable when asked about depression or any other sensitive personal issue when checking in for a medical visit?

Released: 7-Mar-2022 3:20 PM EST
Financial Strain Linked to Increased Risk of Death in Older Adults Recovering from Heart Attack, UM School of Medicine Study Finds
University of Maryland School of Medicine

Older adults who report being under severe financial strain were substantially more likely to die within six months of having a heart attack compared to those with moderate or no financial strain, according to a new study led by University of Maryland School of Medicine (UMSOM) researchers.

3-Mar-2022 12:05 PM EST
Could a Community-Based Approach to Genetic Testing Help African Americans Reduce Risks of Chronic Kidney Disease?
Mount Sinai Health System

In 2010, scientists discovered that African Americans who are born with certain variants of a gene called apolipoprotein L1 (APOL1) have a higher-than-average risk for experiencing chronic kidney disease (CKD). Now, in a new study of African Americans with hypertension, researchers at the Icahn School of Medicine at Mount Sinai find that a community-based approach to reporting APOL1 genetic test results back to individuals may have beneficial effects.

2-Mar-2022 1:35 PM EST
Combination treatment is effective for treating smokers who drink heavily
University of Chicago Medical Center

A study on smokers who drink heavily finds that a combination treatment of the drug varenicline and nicotine replacement therapy is more effective for smoking cessation, and that efforts to quit smoking can indirectly lead to reduced drinking rates.

Released: 2-Mar-2022 9:05 PM EST
Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research
University of Utah

Results from a new clinical trial demonstrate that an eight-week mindfulness-based therapy—Mindfulness-Oriented Recovery Enhancement (MORE)—decreased opioid use and misuse while reducing chronic pain symptoms, with effects lasting as long as nine months.

Newswise: Black overdose death rate exceeds white rate in U.S. for first time in 20 years
Released: 2-Mar-2022 3:45 PM EST
Black overdose death rate exceeds white rate in U.S. for first time in 20 years
University of California, Los Angeles (UCLA), Health Sciences

In 2020, the first year of the COVID-19 pandemic, the rate of drug overdose deaths among Black Americans surpassed that of whites for the first time since 1999 — a sharp reversal of the situation a decade earlier, when rates were twice as high for whites as for Blacks.

Released: 1-Mar-2022 3:45 PM EST
Investigating The Effects of Critical Illness in Early Childhood On Neurocognitive Outcomes
University of Pennsylvania School of Nursing

Approximately 23,700 children in the U.S. undergo invasive mechanical ventilation for acute respiratory failure annually. Although most survive, little is known if they have worse long-term neurocognitive function than children who do not undergo such procedures. There are concerns about neurotoxic effects of critical illness and its treatment on the developing brain. Therefore, infants and young children may be uniquely susceptible to adverse neurocognitive outcomes after invasive mechanical ventilation.

Newswise: Patient Safety Program Reduces Unnecessary Antibiotic Use in Long-Term Care Facilities
Released: 28-Feb-2022 12:05 PM EST
Patient Safety Program Reduces Unnecessary Antibiotic Use in Long-Term Care Facilities
Johns Hopkins Medicine

In early 2021, researchers at Johns Hopkins Medicine and NORC at the University of Chicago showed that the Agency for Healthcare Research and Quality Safety Program for Improving Antibiotic Use successfully helped more than 400 U.S. hospitals ensure that patients only received antibiotics when needed, and then, only in the correct amounts and for the prescribed dosage period.

Newswise: Jonsson Comprehensive Cancer Center researcher urges caution on AI in mammography
Released: 25-Feb-2022 2:15 PM EST
Jonsson Comprehensive Cancer Center researcher urges caution on AI in mammography
University of California, Los Angeles (UCLA), Health Sciences

Analyzing breast-cancer tumors with artificial intelligence has the potential to improve healthcare efficiency and outcomes, but doctors should proceed cautiously, according to a new editorial in JAMA Health Forum co-written by Dr. Joann G. Elmore, a researcher at the UCLA Jonsson Comprehensive Cancer Center.

Newswise: New Artificial Intelligence Tool Detects Often Overlooked Heart Diseases
Released: 23-Feb-2022 8:05 PM EST
New Artificial Intelligence Tool Detects Often Overlooked Heart Diseases
Cedars-Sinai

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis. The new findings were published in JAMA Cardiology.

   
Released: 23-Feb-2022 5:05 PM EST
Child Abuse Actually Decreased During COVID. Here’s Why
Tufts University

A review of available data suggests that there was not a significant rise in child abuse related to COVID-19. Robert Sege of Tufts University School of Medicine and Tufts Medical explains the "missing epidemic of child abuse" in a recent JAMA Pediatrics viewpoint.

Released: 23-Feb-2022 12:45 PM EST
Extreme heat linked to increase in mental health emergency care
Boston University School of Medicine

During periods of extreme heat, clinicians should expect to see an increase in patients requiring mental health services, according to a new study led by Boston University School of Public Health researchers.

Newswise: Patients with rare skin cancer, Merkel cell carcinoma, face 40% recurrence rate
21-Feb-2022 3:35 PM EST
Patients with rare skin cancer, Merkel cell carcinoma, face 40% recurrence rate
University of Washington School of Medicine

Patients treated for Merkel cell carcinoma face a five-year recurrence rate of 40%—markedly higher than recurrence rates for other skin cancers, according to new research in JAMA Dermatology. As well, 95% of recurrences happened in the first 3 years, suggesting surveillance should be focused in that span.

Released: 23-Feb-2022 9:00 AM EST
More adults are falling every year, despite prevention efforts
University of Michigan

Falls are a leading cause of hospitalization and institutionalization for older adults in the U.S. and fall prevention efforts are an important part of geriatric education and health.

Newswise: 10-Year Study Results Find Patient Outcomes Similar for Two CABG Procedures
Released: 17-Feb-2022 1:25 PM EST
10-Year Study Results Find Patient Outcomes Similar for Two CABG Procedures
Stony Brook University

A new study that monitors patients who received “on-pump” or “off-pump” coronary artery bypass grafting (CABG) over a 10-year period reveals that outcomes between the two forms of heart bypass surgery are not much different. The findings are published in JAMA Surgery.

Newswise: MRI may lower breast cancer deaths from variants in 3 genes
15-Feb-2022 1:05 PM EST
MRI may lower breast cancer deaths from variants in 3 genes
University of Washington School of Medicine

Annual MRI screenings starting at ages 30 to 35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes (ATM, CHEK2, PALB2), according to a newly published comparative modeling analysis. The findings will be published Feb. 17 in JAMA Oncology.

Released: 16-Feb-2022 2:05 PM EST
Too soon to lift mask mandates for most elementary schools in U.S., study finds
Harvard T.H. Chan School of Public Health

Before lifting mask mandates in elementary schools in the U.S., local COVID-19 case rates should be far below current rates to avoid the risk of increased transmission among students, staff, and families, according to a study led by researchers at Harvard T.H. Chan School of Public Health and Massachusetts General Hospital (MGH).

Newswise: University of Miami Miller School Investigators Compare Recovery from Open Versus Robotic Bladder Removal Surgery
15-Feb-2022 10:30 AM EST
University of Miami Miller School Investigators Compare Recovery from Open Versus Robotic Bladder Removal Surgery
University of Miami Health System, Miller School of Medicine

Patients undergoing bladder removal surgery, known as cystectomy, need from three to six months to recover regardless of whether they have robot-assisted radical cystectomy or the traditional open approach, according to a multicenter study led by Miller School investigators and published in JAMA Network Open.

14-Feb-2022 1:55 PM EST
Where Children Live Linked to Delayed Access to Surgical Care
Ann and Robert H. Lurie Children's Hospital of Chicago

A new study from Ann & Robert H. Lurie Children’s Hospital of Chicago found that children from less resourced neighborhoods were at increased odds of presenting with complicated appendicitis, an indicator of delayed access to surgical care. This is the first pediatric study to link many neighborhood-level factors that influence health – such as quality of schools, housing, safety, and economic opportunity – to timely surgical care access.

Newswise: Pandemic Upends Breast Cancer Diagnoses
Released: 15-Feb-2022 1:00 PM EST
Pandemic Upends Breast Cancer Diagnoses
UC San Diego Health

UC San Diego Health researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pandemic, discovering fewer of the former and more of the latter as patients delayed care.

Newswise: Multi-Country African Research Reports High Rates of COVID-19-Related Deaths Among Hospitalized Children and Adolescents
Released: 15-Feb-2022 11:55 AM EST
Multi-Country African Research Reports High Rates of COVID-19-Related Deaths Among Hospitalized Children and Adolescents
University of Maryland School of Medicine

African children and adolescents hospitalized with COVID-19 experience much higher mortality rates than Europeans or North Americans, according to a study conducted by the Institute of Human Virology at the University of Maryland School of Medicine and the Institute of Human Virology Nigeria.

Newswise: Rare Insight: A New Approach Optimizes Hepatoblastoma Cancer Treatment
Released: 14-Feb-2022 5:05 PM EST
Rare Insight: A New Approach Optimizes Hepatoblastoma Cancer Treatment
Children's Hospital Los Angeles

A new study at Children’s Hospital Los Angeles independently verified the value of a system that assesses hepatoblastoma risk in children. Hepatoblastoma is a rare childhood liver cancer, usually seen within the first three years of a child’s life with 50 to 70 cases occurring in the U.S. each year.

11-Feb-2022 1:00 PM EST
Study Suggests Misalignment Between Tax Subsidies for Nonprofit Hospitals and the Community Benefit These Hospitals Provide
Johns Hopkins University Carey Business School

A study led by researchers at Johns Hopkins Carey Business School found a surprising misalignment between the tax subsidies received by nonprofit hospitals in the United States and the community benefit that these hospitals provide.

   
Newswise: Follow-up costs can add up if a free cancer screening shows a potential problem
Released: 14-Feb-2022 8:05 AM EST
Follow-up costs can add up if a free cancer screening shows a potential problem
Michigan Medicine - University of Michigan

Several recent studies measure the out-of-pocket costs that patients face for necessary follow-up tests after getting abnormal results on free screening for colon, cervical, lung or breast cancer.

Released: 10-Feb-2022 12:45 PM EST
全球性研究发现代谢综合征可增加COVID-19住院患者发生急性呼吸窘迫综合征和死亡的风险
Mayo Clinic

根据一项发表在《美国医学会杂志—网络开放》(JAMA Network Open)上的全球性研究,存在高血压、肥胖症、糖尿病或其他代谢综合征相关疾病的COVID-19(2019冠状病毒病)住院患者发生急性呼吸窘迫综合征和死亡的风险明显升高。

Released: 10-Feb-2022 12:40 PM EST
دراسة عالمية تجد أن متلازمة التمثيل الغذائي تزيد من خطر الإصابة بمتلازمة ضيق النفس الحادة، والوفاة لدى المرضى الذين يدخلون المستشفى بفيروس كورونا المستجد (كوفيد-19)
Mayo Clinic

ولاية مينيسوتا- إنّ المرضى الذين أُدخِلوا إلى المستشفى بفيروس كورونا المستجد (كوفيد-19) والمصابين بمزيج من ارتفاع ضغط الدم أو السُمنة أو السكري أو غيرها من الحالات المرتبطة بمتلازمة التمثيل الغذائي هم أكثر عرضة لخطر الإصابة بمتلازمة ضيق النفس الحادة والوفاة، وفقًا لدراسة دولية نُشرت في مجلة جاما نتوورك اوبن.

Released: 10-Feb-2022 12:35 PM EST
Um estudo global descobriu que a síndrome metabólica aumentou o risco de síndrome do desconforto respiratório agudo e morte em pacientes hospitalizados com COVID-19
Mayo Clinic

Pacientes hospitalizados com COVID-19 que possuíam uma combinação de pressão alta, obesidade, diabetes ou outras condições associadas à síndrome metabólica corriam um risco muito maior para síndrome do desconforto respiratório agudo e morte.

Released: 10-Feb-2022 12:30 PM EST
Estudio mundial descubrió que síndrome metabólico aumentó riesgo de síndrome de dificultad respiratoria aguda y muerte en pacientes hospitalizados por COVID-19
Mayo Clinic

Los pacientes hospitalizados por COVID-19 y que tenían una mezcla de hipertensión, obesidad, diabetes u otras afecciones relacionadas con el síndrome metabólico corrieron un riesgo mucho mayor de desarrollar el síndrome de dificultad respiratoria aguda y de morir.

Newswise: UTSW study finds it safe to give clot-busting drug to stroke patients who took blood thinners
8-Feb-2022 5:05 PM EST
UTSW study finds it safe to give clot-busting drug to stroke patients who took blood thinners
UT Southwestern Medical Center

Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows. The results run counter to the common practice of withholding the clot-busting drug to these patients due to concerns over complications from bleeding.

Newswise:Video Embedded covid-19-linked-to-serious-health-complications-during-pregnancy
VIDEO
Released: 7-Feb-2022 11:00 AM EST
COVID-19 Linked to Serious Health Complications During Pregnancy
University of Utah Health

Pregnant individuals infected with SARS-CoV-2, the virus that causes COVID-19, are about 40% more likely to develop serious complications or die during pregnancy than those who aren’t infected with the virus, according to a nationwide study led by a University of Utah Health obstetrician.

3-Feb-2022 4:05 PM EST
Getting more sleep reduces caloric intake, a game changer for weight loss programs
University of Chicago Medical Center

In a randomized clinical trial, overweight adults who increased their nightly sleep duration by about an hour reduced their daily caloric intake by an average of 270 kcal, which would lead to weight loss over time.

Released: 7-Feb-2022 9:50 AM EST
Prevention suffers when doctors drop out of Medicare’s ACO program
Michigan Medicine - University of Michigan

For 10 years, Medicare has offered doctors and their practices extra money if they joined groups called Accountable Care Organizations and improved the quality of care they provided to older patients covered by traditional Medicare, while also focusing on the cost of their care. But a new study finds that those quality gains erode quickly when physician groups leave ACOs – which many have done in the past two years.

Released: 4-Feb-2022 11:20 AM EST
Shorter Treatment is Better for Young Children with Outpatient Pneumonia
Vanderbilt University Medical Center

Five days of antibiotics is superior to 10 days for children with community-acquired pneumonia who are not hospitalized, according to a study published in JAMA Pediatrics.

Newswise: Yale Cancer Center Study Suggests Improved Diagnostic Testing Needed to Guide HER2 Breast Cancer Treatment
2-Feb-2022 8:05 AM EST
Yale Cancer Center Study Suggests Improved Diagnostic Testing Needed to Guide HER2 Breast Cancer Treatment
Yale Cancer Center/Smilow Cancer Hospital

A new study by researchers at Yale Cancer Center shows using current standard human epidermal growth factor receptor 2 (HER2) assays as a diagnostic test may result in a mis-assignment of patients for treatment for breast cancer with a promising new drug.

Released: 2-Feb-2022 12:30 PM EST
Study finds concerning variations in care between physicians of the same specialty and in the same city, delivering care in the same clinical scenarios
Harvard Medical School

Some physicians are much more likely to deliver appropriate care than others, even in clinical situations where guidelines for appropriate care are clear. Notable—at times dramatic—differences were found across 14 common clinical scenarios representing seven specialties. The findings highlight the importance of understanding the reasons for these variations and developing ways to minimize them to improve the value of care.

Newswise: Social Isolation and Loneliness Increase Heart Disease Risk in Senior Women
31-Jan-2022 5:05 PM EST
Social Isolation and Loneliness Increase Heart Disease Risk in Senior Women
University of California San Diego

Data from a UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study point to as much as a 27% increase in heart disease risk in postmenopausal women who experience both high levels of social isolation and loneliness.

Newswise: Greater body fat a risk factor for reduced thinking and memory ability
Released: 1-Feb-2022 2:20 PM EST
Greater body fat a risk factor for reduced thinking and memory ability
McMaster University

A new study has found that greater body fat is a risk factor for reduced cognitive function, such as processing speed, in adults. Even when the researchers took cardiovascular risk factors (such as diabetes or high blood pressure) or vascular brain injury into account, the association between body fat and lower cognitive scores remained. This suggests other not yet confirmed pathways that linked excess body fat to reduced cognitive function.

Newswise:Video Embedded study-examines-years-of-life-lost-for-adolescents-young-adults-to-unintentional-drug-overdose
VIDEO
28-Jan-2022 5:00 PM EST
Study Examines Years Of Life Lost For Adolescents, Young Adults To Unintentional Drug Overdose
Ohio State University Wexner Medical Center

In a first-ever study, researchers at The Ohio State University Wexner Medical Center and College of Medicine examined the unintentional drug overdose mortality in Years of Life Lost among adolescents and young people in the United States. Study findings are published online in the journal JAMA Pediatrics.

Released: 27-Jan-2022 2:55 PM EST
The Effects of Pediatric Critical Illness on Absenteeism
University of Pennsylvania School of Nursing

Children who survive critical illness and their parents commonly experience physical, emotional, and cognitive conditions as a result of the critical illness. These effects can also include prolonged absences from school and/or work. What has not been fully understood is the rate and duration of school absences among these children and work absences among their caregivers.

Newswise: Flowered Steering: How Well Do Drivers Fare After Smoking Cannabis?
Released: 26-Jan-2022 2:25 PM EST
Flowered Steering: How Well Do Drivers Fare After Smoking Cannabis?
UC San Diego Health

Novel trial measured simulated driving performance of persons after cannabis use, revealing sharply differentiated levels of ability and perception of skills.

24-Jan-2022 3:00 AM EST
New Study Validates Benefits of Convalescent Plasma for Some COVID-19 Patients
NYU Langone Health

Transfusions of blood plasma donated by people who have already recovered from infection with the pandemic virus may help other patients hospitalized with COVID-19, a new international study shows.

Newswise: Most “Pathogenic” Genetic Variants Have a Low Risk of Causing Disease
21-Jan-2022 2:05 PM EST
Most “Pathogenic” Genetic Variants Have a Low Risk of Causing Disease
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai discovered that the chance a pathogenic genetic variant may actually cause a disease is relatively low - about 7 percent. They also found that some variants, such as those associated with breast cancer, are linked to a wide range of risks for disease. The results could alter the way the risks associated with these variants are reported, and one day, help guide the way physicians interpret genetic testing results.

Newswise: Use of Alzheimer’s drug aducanumab raises concerns about Medicare spending
Released: 24-Jan-2022 9:05 PM EST
Use of Alzheimer’s drug aducanumab raises concerns about Medicare spending
University of California, Los Angeles (UCLA), Health Sciences

A cost analysis of the controversial new Alzheimer’s disease drug aducanumab shows that ancillary care services account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.

Newswise: Access to vital health services fell during COVID, particularly for poorer Americans
Released: 24-Jan-2022 4:25 PM EST
Access to vital health services fell during COVID, particularly for poorer Americans
University of California, Los Angeles (UCLA), Health Sciences

Some of the most socioeconomically disadvantaged patients — those with Medicaid or Medicare-Medicaid dual eligibility insurance — were far less likely than those with other insurance plans to return to using outpatient services at rates approaching normal, pre-pandemic levels.

Newswise: Children with Cancer and Other Special Needs Deserve Support During Online Learning
Released: 24-Jan-2022 9:40 AM EST
Children with Cancer and Other Special Needs Deserve Support During Online Learning
Johns Hopkins Medicine

Thousands of schools transitioned to online learning in 2020 due to the COVID-19 pandemic, during which time many children with cancer and other chronic health needs, as well as those with special education needs, faced significant challenges to learning online. An opinion paper by Johns Hopkins experts, published Jan. 4 in the journal JAMA Pediatrics, highlights some of the issues faced by families and offers suggestions to move forward.



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