Rutgers researchers hope their genome-assembly tool will spur the development of new treatments for bacterial infections.
Antibiotic resistant bacteria pose of the greatest threats to global public health. New research has the potential to reduce the amount of antibiotics used in the clinic and may pave the way for the discovery of new antibiotics that change growth rate and energy levels in bacteria.
The diagnosis and treatment of long COVID syndrome (LCS) is still very difficult, and there is only little knowledge about the factors causing accompanying symptoms.
The incredibly fast spread of COVID-19 throughout the world brought to light a very important fact: we need better methods to diagnose infectious diseases quickly and efficiently.
Japan’s government has drawn criticism from some of the nation’s researchers following a new analysis that shows Japan has for years been lagging in the field of infectious diseases research, including after the COVID-19 pandemic had hit.
Researchers at UBC’s Life Sciences Institute have identified a compound that shows early promise at halting infections from a range of coronaviruses, including all variants of SARS-CoV-2 and the common cold.
Men are at an increased risk of a severe bout of COVID-19 compared to women.
Onset of the COVID-19 pandemic was associated with increased hospitalizations with mental health diagnoses among adolescents, according to the results of this study that included eight children’s hospitals in the United States and France.
The federal agency that protects against pandemics and bioterrorism has elevated Texas Biomedical Research Institute into the top ranks of its national readiness and preparedness network. The new designation as a prime contractor opens Texas Biomed to a portfolio of up to $100 million in funding over five years through the Biomedical Advanced Research and Development Authority (BARDA).
Working night shifts is associated with several negative health outcomes, including an increased risk of infections.
In a global study, researchers have identified that most reservoirs of rodent-borne diseases tend to live exclusively or occasionally in or near human dwellings, show large fluctuations in their numbers, and/or are hunted for meat or fur.
Pesquisadores da Mayo Clinic dizem que o anticorpo monoclonal bebtelovimabe (já autorizado pela Food and Drug Administration para uso emergencial na variante ômicron da COVID-19) é uma opção confiável para tratar a BA.2 e outras subvariantes da COVID-19. As descobertas do estudo retrospectivo realizado vários locais, envolvendo 3.607 pacientes de alto risco foram publicadas na revista médica Journal of Infectious Diseases.
Los investigadores de Mayo Clinic informan que el anticuerpo monoclonal bebtelovimab, ya autorizado por la Administración de Alimentos y Medicamentos de Estados Unidos para usar en emergencias de la variante ómicron de la COVID-19, es una alternativa confiable para tratar a la BA.2 y otras subvariantes de la COVID-19. Los resultados del estudio retrospectivo que se realizó en varios sitios con 3607 pacientes de alto riesgo se publicaron en Journal of Infectious Diseases (Revista de Enfermedades Infecciosas).
Researchers trained five classification algorithms to create an accurate model to predict COVID-19 test results. Results identify the key symptom features associated with COVID-19 infection and provide a way for rapid screening and cost effective infection detection. Findings reveal that number of days experiencing symptoms such as fever and difficulty breathing play a large role in COVID-19 test results. Findings also show that molecular tests have much narrower post-symptom onset days compared to post-symptom onset days of serology tests. As a result, the molecular test has the lowest positive rate because it measures current infection.
مدينة روتشستر، ولاية مينيسوتا - يقول باحثو مايو كلينك إن الجسم المضاد أحادي النسيلة ببتيلوفيماب، المُرخص بالفعل من قبل إدارة الغذاء والدواء الأمريكية للاستخدام في حالات الطوارئ الخاصة بمتحور أوميكرون من فيروس كورونا المستجد (كوفيد-19)، هو خيار موثوق لعلاج سلالة BA.2 والمتحورات الفرعية الأخرى لفيروس كورونا المستجد (كوفيد-19). ونتائج دراستهم الاسترجاعية متعددة المواقع والتي شملت 3,607 مريضًا معرضين لمخاطر عالية، منشورة في مجلة الأمراض المعدية.
Reasons underlying hesitancy to get vaccinated against COVID-19 may be associated with increased risks of traffic accidents according to a new study in The American Journal of Medicine, published by Elsevier.
In early 2020, before COVID-19 vaccines and effective treatments were widely available, universal mask wearing was a central strategy for preventing the transmission of COVID-19. But hospitals and other settings with mask mandates faced a challenge.
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
An analysis of the first large mpox outbreak in North America found that early, sustained engagement and rapid offering of preexposure vaccination to affected communities successfully controlled the spread of the outbreak. The analysis is published in Annals of Internal Medicine.
A retrospective cohort study of more than 44,000 nonhospitalized persons diagnosed with COVID-19 found that nirmatrelvir plus ritonavir reduced the overall risk of hospitalization and death. The study is published in Annals of Internal Medicine.
MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state.
LJI Instructor Annie Elong Ngono, Ph.D., has spearheaded important studies into the immune response to deadly pathogens such as dengue virus. Now, this dedication to global health and virology has earned her acceptance to the Global Virus Network's (GVN) highly selective Rising Star Mentorship Program.
Enacting Medicaid expansion in Texas and increasing the use of preventive and antiviral medications could result in a decline of new HIV infections among young Black gay, bisexual, and other men who have sex with men (MSM) in Houston, reports a study in the January issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Investigators from the Smidt Heart Institute at Cedars-Sinai validated the link between a debilitating heart condition and COVID-19 and, to a lesser extent, a novel link between the same condition and COVID-19 vaccination.
Adult hospitalisations from Omicron-related SARS-CoV-2 (COVID-19) were less severe than Delta and the Pfizer-BioNTech vaccine remains effective in preventing not only hospitalisation, but severe patient outcomes associated with COVID-19, two new research studies have found.
The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been devastating the entire world.
Losing too much weight when infected with COVID-19 has been linked to worse outcomes.
Irvine, Calif., Dec. 8, 2022 — The National Academy of Inventors has named two University of California, Irvine researchers as fellows for 2022. Philip Felgner, a pioneer in the development of lifesaving mRNA vaccines, and Payam Heydari, a prolific creator of cutting-edge microelectronics technologies, were both recognized for inventions that have made tangible impact on quality of life, economic development and the welfare of society.
Study is one of the first to associate long COVID symptoms with changes in gene expression during acute COVID-19
Using a new analytical method, Empa researchers have tracked viruses as they pass through face masks and compared their failure on the filter layers of different types of masks. The new method should now accelerate the development of surfaces that can kill viruses, the team writes in the journal Scientific Reports.
人乳头状瘤病毒(HPV)具有100多种变异株，感染这种病毒通常会引发疣。HPV的某些变异株还可导致宫颈癌、肛门癌、阴茎癌、阴道癌、外阴癌以及咽喉癌。
Scientists at Dana-Farber Cancer Institute have developed a drug that potently neutralizes SARS-CoV-2, the COVID-19 coronavirus, and is equally effective against the Omicron variant and every other tested variant. The drug is designed in such a way that natural selection to maintain infectiousness of the virus should also maintain the drug’s activity against future variants.
Investigators at Cedars-Sinai conduct more than 2,500 research projects annually, and many of these studies have resulted in new treatments or have opened the door to future innovations.
Individuals who, despite having been vaccinated against COVID-19, develop the disease and are hospitalized are less likely to go to an intensive care unit (ICU), more likely to have a shorter hospital stay, and less likely to die in the hospital than individuals hospitalized for COVID who were never vaccinated, according to a national study from the Centers for Disease Control and Prevention’s VISION Network.
Ticks can transmit many different pathogens such as viruses, bacteria, and parasites.
"Vaccines such as JYNNEOS should be able to induce T cells that also recognize mpox and can provide protection from severe disease."
Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news.
Those on the front line of the Covid pandemic need mental health support to help them recover from, or manage, the stress and trauma they faced - according to University of East Anglia research.
The Global Virus Network (GVN) announced eleven members of the 2022 GVN Rising Star Mentorship Program. The newly elected members span eight countries around the globe.
Researchers at Washington University School of Medicine in St. Louis have shown that the cancer therapy known as CAR-T can be applied to multiple sclerosis (MS), an autoimmune disease of the nervous system. The findings extend the powerful tool of immunotherapy to autoimmune diseases, a class of diseases that are often debilitating and difficult to treat.
By August 2022, most children and adults younger than 60 years in Canada had been exposed to SARS-CoV-2 through a combination of vaccination and infection, according to a large study looking at blood antibodies published in CMAJ (Canadian Medical Association Journal)
Researchers at The Tisch Cancer Institute uncovered inflammatory markers that may predict which COVID-19 patients are more likely to respond to therapies like the anti-cancer drug pacritinib, according to phase 2 trial results published in JAMA Network Open in December.
CRISPR, the Nobel Prize-winning gene editing technology, is poised to have a profound impact on the fields of microbiology and medicine yet again. A team led by CRISPR pioneers Jennifer Doudna and Jill Banfield has developed a tool to edit the genomes of bacteria-infecting viruses called bacteriophages using a rare form of CRISPR. The ability to easily engineer custom-designed phages will help researchers treat dangerous drug-resistant infections and control microbiomes without antibiotics or harsh chemicals.
The precise relationship between vaccine hesitancy and COVID-19 vaccination side effects has not previously been explored in vaccinated persons. A fundamental question arises in regard to the directionality of this vaccine hesitancy-vaccine side effect link, namely which variable predicts which. One possibility is that side effects from an earlier dose predict one’s vaccine hesitancy towards a later dose. Alternatively, one’s psychological negativity (hesitancy) towards an earlier dose could predict subsequent side effects from a later vaccination dose. The latter direction reflects a Nocebo effect, i.e., side effects driven by psychological factors rather than by an active treatment component. Results showed only the latter direction to be true. Namely, only earlier vaccine hesitancy towards the second COVID-19 dose predicted subsequent nocebo side-effects following the booster vaccination. To put this in perspective up to 16% of one’s vaccine side effects were explained by earlier va
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