A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson’s disease, according to new research from Iowa State University. The effect is particularly dramatic for young-to-middle-age adults.
Learning by taking practice tests, a strategy known as retrieval practice, can protect memory against the negative effects of stress, report scientists from Tufts University in a new study published in Science on Nov. 25.
Mental disorders and physical diseases frequently go hand in hand. For the first time, psychologists at the University of Basel and Ruhr University Bochum have identified temporal patterns in young people: arthritis and diseases of the digestive system are more common after depression, while anxiety disorders tend to be followed by skin diseases.
A study led jointly by research student Elham Taha from the laboratory of Prof. Kobi Rosenblum at the University of Haifa, and Christopher Heise from the laboratory of Professor Carlo Sala at the University of Milan, in cooperation with other European researchers. In a surprising finding, the study showed that a genetic change in the protein eEF2K creates resistance to epileptic attacks, thereby creating the possibility of a new treatment for the disease
Older baby boomers—those born between 1945 and 1954—are the “stroke-healthiest generation,” according to a Rutgers study that found the lowest incidence of ischemic stroke in this age group within the past 20 years. In contrast, the rate of stroke more than doubled in Generation X, people born between 1965 and 1974, during the same time period.
When traditional sequencing yielded no genetic drivers, pediatric cancer researchers identified changes at the epigenetic level that suggest a critical marker for predicting prognosis.
A multi-institutional group of researchers, led by investigators at Children’s Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.
Sanford Burnham Prebys Medical Discovery Institute (SBP) has announced that Huaxi Xu, Ph.D., has been named the Jeanne and Gary Herberger Leadership Chair in Neuroscience at the institute.
A team of biomedical engineering researchers at the University of Arkansas have identified a cause of fluid swelling of the brain, or cellular edema, that occurs during a concussion.
A team of scientists led by researchers at the University of Georgia has developed a new mouse model that closely mimics fetal brain abnormalities caused by the Zika virus in humans.
A woman had a cold virus injected into her brain tumor in an effort to eradicate it, making her the first person in the United States to participate in a clinical trial using this method, which incorporates immunotherapy, and was performed by doctors at the University of Arkansas for Medical Sciences (UAMS).
Humans, as well as many other organisms, possess internal clocks. The exact timing, however, can differ between individuals – for instance, some people are early risers whereas others are "night owls". Neurobiologist Kristin Tessmar-Raible and her team at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and Medical University of Vienna investigated that underlie such timing variations or "chronotypes". The non-biting midge Clunio marinus has two internal clocks, since it times its reproduction according to sun and moon. The team around Tessmar-Raible and Postdoc Tobias Kaiser were now able to identify relevant genes for this adaptation, and published their results in the current issue of "Nature".
New technologies are giving researchers unprecedented opportunities to explore how the brain processes, utilizes, stores and retrieves information. But without a coherent strategy to analyze, manage and understand the data generated by these new tools, advancements in the field will be limited. Berkeley Lab researchers and their collaborators offer a plan to overcome these big data challenges.
A team of neuroscience and biochemistry researchers at Stony Brook University have made a novel discovery that illustrates for the first time the difference between amyloid buildup in brain blood vessels and amyloid buildup around brain neurons.
The same compounds that give plants and vegetables their vibrant colors might be able to bolster brain functioning in older adults, according to a recent study from the University of Georgia.
Beth Israel Deaconess Medical Center (BIDMC) researchers have identified previously unknown neural circuitry that plays a role in promoting satiety, the feeling of having had enough to eat. The discovery revises the current models for homeostatic control – the mechanisms by which the brain maintains the body’s status quo – of feeding behavior. Published online today in Nature Neuroscience, the findings offer new insight into the regulation of hunger and satiety and could help researchers find solutions to the ongoing obesity epidemic.
In a hopeful sign for the health of the nation’s brains, the percentage of American seniors with dementia is dropping, a new study finds.
The downward trend has emerged despite something else the study shows: a rising tide of three factors that are thought to raise dementia risk by interfering with brain blood flow, namely diabetes, high blood pressure and obesity.
Exercise is key for Parkinson’s patients but it can be difficult to get them motivated and excited about treadmills, weights, and stationary bikes. At Rock Steady NYIT, health care professionals, as well as student physicians and physical therapy students, lead participants through classes with group activities, games, and boxing exercises designed to improve their physical and mental stamina.
Study Highlights
• Designed a smart drug that only targets and kills GBM brain cancer cells.
• Validated a compound that sensitizes GBM tumors to chemotherapy and results in a significant extension of life in an animal model.
Scientists have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in amyotrophic lateral sclerosis (ALS) — as well as a molecule that interferes with this helpful process.
Often called the suicide headache because of the excruciating intensity of the pain, cluster headaches are three times more likely to strike men than women.
The ASN Foundation for Kidney Research (ASN Foundation) is proud to announce the public launch of its Securing the Future Campaign during ASN Kidney Week 2016. This campaign coincides with the 50th anniversary of the American Society of Nephrology (ASN) and the 20th anniversary of the Career Development Grants Program.
• Amit X. Garg, MD, PhD will be presented with the ASN-AHA Young Investigator Award during ASN Kidney Week 2016, the world’s premier nephrology meeting where more than 13,000 kidney health professionals from around the world will gather in Chicago, IL from November 15–20.
– Elizabeth Loftus, Distinguished Professor of psychology & social behavior and criminology, law & society at the University of California, Irvine, was awarded the international John Maddox Prize for Standing up for Science today in London. Best known for her groundbreaking work on the “misinformation effect” – in which the memories of eyewitnesses are altered by exposure to incorrect information about events – she was also honored for her pioneering research on the creation and nature of false memories.
It has long been known to science that women find it easier than men to multitask and switch between tasks. But identifying exactly which areas of male and female brains respond differently and why has so far been unclear.
A study using Barbies and Transformers finds that men are better at recognizing Transformer faces while women are better at recognizing Barbie faces, supporting the theory that experience plays an important role in facial recognition.
We humans walk with our feet. This is true, but not entirely. Walking, as part of locomotion, is a coordinated whole-body movement that involves both the arms and legs. Researchers at the Biozentrum of the University of Basel and the Friedrich Miescher Institute for Biomedical Research have identified different subpopulations of neurons in the spinal cord with long projections. Published in Neuron, the results show that these neurons coordinate movement of arms and legs and ensure a stable body posture during locomotion.
A new study shows a link between mothers with rheumatoid arthritis and children with epilepsy. The study is published in the November 16, 2016, online issue of Neurology®, a medical journal of the American Academy of Neurology. Rheumatoid arthritis (RA) is an autoimmune disease that causes the body’s own immune system to attack the joints. It differs from osteoarthritis, which is caused by wear and tear on the joints.
Under a five-year, $2.5 million grant from the National Institute on Minority Health and Health Disparities, a team of University of Michigan researchers and community partners is embarking on a novel project to increase acute stroke treatment rates in the community of Flint, Michigan.
A new study in rats could begin to explain why allergies during pregnancy are linked to higher risks for attention-deficit hyperactivity disorder and autism in children.
Researchers at UT Southwestern Medical Center report the most detailed 3-D structure to date of the brain receptor that binds and responds to the chemical at the root of marijuana’s high.
In new findings that could have an impact the development of therapies for a number of currently untreatable brain disorders such as Parkinson’s and Huntington’s diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found for the first time that a specific signaling circuit in the brain is deeply involved in motor activity.
New Northwestern Medicine research on the brains of individuals 90 years and older who had superior memories until their deaths revealed widespread and dense Alzheimer’s plaques and tangles in some cases, considered full-blown Alzheimer’s pathology.
An experimental cancer imaging tool that makes tumors glow brightly during surgery has shown promise again in a new Penn Medicine clinical study, this time in patients with brain cancer. The fluorescent dye technique, originally developed by surgeons at the Penn Center for Precision Surgery to treat lung cancer, illuminated brain tumors in real-time during surgery, helping physicians distinguish between healthy and cancerous tissue
A new animal model developed at Penn Medicine using tau tangles isolated from the brains of Alzheimer’s patients rather than synthetic tau tangles paints a closer picture of the tau pathology in the AD brain
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered that mutations in PTEN affect the assembly of connections between two brain areas important for the processing of social cues: the prefrontal cortex, an area of the brain associated with complex cognitive processes such as moderating social behavior, and the amygdala, which plays a role in emotional processing.
Indiana University neuroscientist Andrea Hohmann took the stage at a press conference Nov. 14 in San Diego to discuss research conducted at IU that has found evidence that the brain’s cannabis receptors may be used to treat chronic pain without the side effects associated with opioid-based pain relievers or medical marijuana.
Aaron W. McGee, Ph.D., assistant professor at the UofL School of Medicine, has received the Disney Award for Amblyopia Research from Research to Prevent Blindness. McGee will use the award to investigate approaches for improving recovery from amblyopia, or “lazy eye."
Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience. “Reconnecting Eye to Brain” is a comprehensive assessment of what scientists know about optic nerve development, regeneration, and reconnection. The report was based on input gathered during the Oct. 16, 2015, panel discussion, titled “Reconnecting Neurons in the Visual System,” sponsored by the National Eye Institute Audacious Goals Initiative (AGI). The panel comprised two dozen leading experts on neural development and regeneration.
Astronauts survive in space by wearing high-tech space suits. But how do brain cancer cells thrive when they migrate to inhospitable sites within the brain?
Douglas Anderson, MD, one of the nation’s most accomplished neurosurgeons, has been appointed chair of the department of neurological surgery of Loyola Medicine and Loyola University Chicago Stritch School of Medicine.
ROCHESTER, Minn. — Research from Mayo Clinic included in the November issue of JAMA Neurology identifies a new biomarker for brain and spinal cord inflammation, allowing for faster diagnosis and treatment of patients.
Researchers have identified a key mechanism linking the master molecular clock in the brain to changes in the external firing activity of those circadian clock neurons. It involves the GSK3 kinase enzyme, which is also the target of mood-stabilizing drugs used to treat bipolar disorder.