A University of Wisconsin-Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell. The cells in question are neurons and make the neurotransmitter dopamine, whose deficiency is the culprit in the widespread movement disorder Parkinson's disease.
To address the deficit of interventions for older children and adolescents with fragile X, MIND Institute researcher Andrea McDuffie and colleagues created an intervention that uses a shared storytelling paradigm and real-time parent coaching, all provided in the home through telecommunications. The small but important study found that the intervention improved adolescent boys’ abilities to produce longer sentences, use more diverse vocabulary and concentrate for longer time periods during conversational interactions.
People who have had a traumatic brain injury (TBI) may still have sleep problems a year and a half after being injured, according to a study published in the April 27, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology. In addition, people with TBI may also be unaware of just how much their sleep is disturbed.
Rio is a California sea lion who can solve IQ tests that many people have trouble passing. In fact, she is so smart that scientists at the Long Marine Lab at the University of California, Santa Cruz designed a series of tests that prove she is the first animal besides humans that can use basic logic (If A=B and B=C then A=C).
A University of Wisconsin-Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome. The condition, called fragile X, has devastating effects on intellectual abilities.
What if a map of the brain could help us decode people's inner thoughts? Scientists at the University of California, Berkeley, have taken a step in that direction by building a "semantic atlas" that shows in vivid colors and multiple dimensions how the human brain organizes language. The atlas identifies brain areas that respond to words that have similar meanings.
Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source
Resistance, stability and flexibility training can improve balance and other functional movements for people diagnosed with multiple sclerosis—and behavior therapy may further improve their quality of life. That’s the premise of a study that builds on previous work suggesting that resistance and flexibility training improved balance and symmetry, which is of particular concern for those experiencing leg weakness.
A group including scientists at The Scripps Research Institute Florida campus has been awarded a grant from the National Institute of Neurological Disorders to study the role of microRNAs in a range of physiological activities, including memory, sleep, synapse function and movement.
Description of Invited Speakers for AANS Annual Scientific Meeting
Review of AANS Annual Scientific Meeting Opening Ceremonies
Univ. of Iowa biologists have homed in on the genes that tell brain cells to grow the tendrils critical for passing messages throughout the body. In a new study, they report certain genes in nearby neurons need to be exact matches in order for the signaling branches to grow properly. Results published in the journal Cell Reports.
A gene known as OSMR plays a key role in driving the growth of glioblastoma tumors, according to a new study led by a McGill University researcher and published in the journal Nature Neuroscience.
Hayden Schaumburg suffered paralysis during a high school football game. After a 10-hour surgery and 47 days at Loyola University Medical Center, he was breathing on his own and able to continue rehabilitation. He returns to Loyola to help raise money for the pediatrics program this June.
A new technique might be used to diagnose neuromuscular disorders such as multiple sclerosis or impairment from concussions by detecting and measuring subtle oscillations in a person's standing posture.
The hormone insulin – usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS. Results reveal a metabolic pathway that can be targeted by new and already approved drugs to treat fragile X patients.
The University of Texas MD Anderson Cancer Center and Helsinn, a Swiss pharmaceutical group focused on building quality cancer care, today announced that they signed a strategic alliance on a broad, multi-years program of clinical studies in cancer supportive and palliative care.
Children whose mothers were nurturing during the preschool years, as opposed to later in childhood, have more robust growth in brain structures associated with learning, memory and stress response than children with less supportive moms, according to research at Washington University School of Medicine in St. Louis.
University of Kansas neuroscientist Jonathan Brumberg has been awarded a $25,000 New Century Scholars Research Grant by the American Speech-Language-Hearing Foundation to develop and test a brain-computer interface (BCI) that will directly control commercially available augmentative and alternative communication (AAC) devices for individuals with profound speech and motor disorders
Epilepsy Laser Surgery Gives Teen Normal Life
Princeton University researchers have found that dopamine - a brain chemical involved in learning, motivation and many other functions - also has a direct role in representing or encoding movement. The finding could help researchers better understand dopamine's role in movement-related disorders such as Parkinson's disease.
Repeated impacts to the heads of high school football players cause measurable changes in their brains, even when no concussion occurs, according to research from UT Southwestern Medical Center’s Peter O’Donnell Jr. Brain Institute and Wake Forest University School of Medicine.
Hearing socially meaningful sounds can change the ear and enable it to better detect those sounds, according to researchers at Georgia State University who studied the phenomenon in green treefrogs.
Alcohol-induced blackouts, defined as memory loss of all or a portion of events that occurred during a drinking episode, are reported by approximately 50 percent of drinkers, and are associated with a wide range of negative consequences, including injury and death. Identifying the factors that contribute to and result from alcohol-induced blackouts is critical for developing effective prevention programs. This manuscript is an updated review of clinical research that has focused on alcohol-induced blackouts. It outlines practical and clinical implications of these findings and provides recommendations for future research.
A study conducted by researchers at Columbia University Medical Center found that older adults who used a hearing aid performed significantly better on cognitive tests than those who did not use a hearing aid, despite having poorer hearing.
Compared to the nicotine patch and a placebo, the smoking cessation aids varenicline (marketed as Chantix in the U.S.) and bupropion (Zyban) do not show a significant increase in neuropsychiatric adverse events, reports an international team of researchers in a study published online April 22 in the journal The Lancet.
Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex.
By turning skin cells into brain neurons, researchers at the Icahn School of Medicine at Mount Sinai have identified that certain tiny molecules aiding in gene expression, known as microRNAs (miRNAs), are under-expressed in the brains of the 14 schizophrenia patients they studied.
Columbia researchers have discovered a new neurodevelopmental syndrome and the genetic mutations that cause it.
Aaron D. Boes, MD, PhD, Clinical Neuroscience Fellow in the Berenson-Allen Center for Noninvasive Brain Stimulation at Beth Israel Deaconess Medical Center (BIDMC) received the 2016 S. Weir Mitchell Award from the American Academy of Neurology (AAN) at a ceremony held at the AAN annual meeting in Vancouver. This prestigious honor recognizes a junior investigator based on a manuscript likely to make a significant contribution to the field of neurology.
Autism experts at University of California San Diego Autism Center of Excellence (ACE) at the School of Medicine will be part of the largest autism study ever undertaken in the United States – an effort to collect information and DNA from 50,000 individuals, ages 3 to 100, with the neurodevelopmental disorder.
Athletes who have medical complaints, like aches and pains, that have no known physical cause may take longer to recover after a concussion, according to a study published in the April 20, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
VANCOUVER, BRITISH COLUMBIA – The American Academy of Neurology (AAN), the world’s largest association of neurologists, is pleased to announce the recipients of the 2016 AAN Research Program. This year’s program has awarded nearly $3 million dollars toward neuroscience research and training. The individual awards will be presented during the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016, at the Vancouver Convention Centre.
Athletes who have medical complaints, like aches and pains, that have no known physical cause may take longer to recover after a concussion, according to a study published in the April 20, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Caltech researchers have mapped out a circuit of neurons that is responsible for motor impairment--such as difficulty walking--in patients with Parkinson's disease.
Rebrand of North America's largest spine registry opens the door for even more cross-specialty data collection.
A protein previously known for its role in kidney function, adaptor protein CD2AP, also plays a significant role in the nervous system, and is associated with a type of neural growth known as collateral sprouting.
Using a novel method, Whitehead Institute researchers have determined how mutations that are not located within genes are identified through genome-wide association studies (GWAS) and can contribute to sporadic Parkinson’s disease, the most common form of the condition. The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.
In an Olympics tennis analogy, when a high degree of accuracy is required, a one-second delay in frontal cortex processing could make the difference between an Olympic gold and silver, according to the researchers.
Researchers have developed a new method to map and track the function of brain circuits affected by autism spectrum disorder (ASD) in boys using brain imaging.
Bestselling author John Grisham was featured on CBS This Morning today discussing his free book called The Tumor, a fictional account of how a real medical technology could impact the future of medicine. The short book is about focused ultrasound, a revolutionary non-invasive therapy with the potential to transform the treatment of a variety of serious medical disorders.
Specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice.
Researchers present data and a simple statistical network model that describe an unanticipated property of newly formed, immature neurons in the dentate gyrus.
Researchers at Roswell Park Cancer Institute (RPCI), in collaboration with investigators from the cooperative group SWOG, have found that use of multivitamins prior to diagnosis may reduce the risk of neuropathy in breast cancer patients treated with the class of drugs known as taxanes. The team will present their findings at the American Association for Cancer Research (AACR) Annual Meeting 2016, to be held April 16-20 in New Orleans.
Researchers at The Ohio State University have pinpointed the area of the brain responsible for recognizing human facial expressions.
The UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of Cambridge, leading to an estimated 40,000 fewer cases of dementia than previously predicted. However, the study, published today in Nature Communications, suggests that the dramatic change has been observed mainly in men.
A study by a University of Delaware researcher shows that incarceration of adult family member can lead to lasting neurological health decline for young female relatives.
Chronic brain diseases such as epilepsy involve disturbances of the brain’s electrical activity. Finding new and better ways to correct them is the dream of millions of patients, their physicians and researchers.
The American Academy of Neurology (AAN) has updated its 2008 guidelines on the use of botulinum toxin for spasticity, cervical dystonia, blepharospasm and migraine headache, based on recent research. The guideline is published in the April 18, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented at the 68th AAN Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.
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