Curated News: JAMA

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Released: 22-Oct-2020 11:30 AM EDT
Toward a New Staging System for Prostate Cancer, and Why it Matters
Michigan Medicine - University of Michigan

The development and validation of a staging system for non-metastatic prostate cancer could help doctors and patients assess treatment options, as well as improve clinical trials.

Released: 22-Oct-2020 11:00 AM EDT
Time is Not on Their Side: Physicians Face Barriers to Voting
UT Southwestern Medical Center

DALLAS – Oct. 22, 2020 – Two new UT Southwestern studies published today report some surprising findings: Only half of practicing physicians are registered to vote, and the most common obstacle faced by resident physicians is the lack of time to vote. The researchers say finding ways to increase voter participation among doctors is critical as the nation tackles health care issues.

   
Released: 21-Oct-2020 8:30 AM EDT
Opioid Use Disorder? Electronic Health Records Help Pinpoint Probable Patients
Florida Atlantic University

A new study suggests that patients with opioid use disorder may be identified using information available in electronic health records, even when diagnostic codes do not reflect this diagnosis. The study demonstrates the utility of proxies coding for DSM-5 criteria from medical records to generate a quantitative DSM-5 score that is associated with opioid use disorder severity. The study methods are unique in deriving a severity score that aims to mirror severity scores from more traditional interview-based diagnostic procedures.

Released: 20-Oct-2020 11:45 AM EDT
Efficacy, politics influence public trust in COVID-19 vaccine
Cornell University

If an initial COVID-19 vaccine is about as effective as a flu shot, uptake by the American public may fall far short of the 70% level needed to achieve herd immunity, new Cornell research suggests.

   
13-Oct-2020 4:55 PM EDT
Nudges Combined with Machine Learning Triples Advanced Care Conversations Among Patients with Cancer
Perelman School of Medicine at the University of Pennsylvania

An electronic nudge to clinicians—triggered by an algorithm that used machine learning methods to flag patients with cancer who would most benefit from a conversation around end-of-life goals—tripled the rate of those discussions.

Released: 14-Oct-2020 12:35 PM EDT
Therapy plus medication better than medication alone in bipolar disorder
University of California, Los Angeles (UCLA), Health Sciences

A review of 39 randomized clinical trials by scientists from UCLA and their colleagues from other institutions has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone.

14-Oct-2020 8:55 AM EDT
Tied to Undiagnosed Aortic Disease, Aortic Dissection in Pregnancy Proves Difficult to Predict
Michigan Medicine - University of Michigan

The 100th report out of the International Registry of Acute Aortic Dissection details the experiences of 29 women who faced this rare life-threatening complication while pregnant.

Released: 14-Oct-2020 8:30 AM EDT
Mount Sinai Researchers Find That Where People Live Can Impact Their Risk for Common Chronic Conditions Including High Blood Pressure and Depression
Mount Sinai Health System

The researchers found that a persons' place of residence substantially influences their risk of uncontrolled chronic disease including high blood pressure and depression

Released: 12-Oct-2020 12:20 PM EDT
Total deaths recorded during the pandemic far exceed those attributed to COVID-19
Virginia Commonwealth University (VCU)

For every two deaths attributed to COVID-19 in the U.S., a third American dies as a result of the pandemic, according to new data publishing Oct. 12 in the Journal of the American Medical Association.

Released: 12-Oct-2020 11:00 AM EDT
Labor epidurals do not cause autism; Safe for mothers and infants, say anesthesiology, obstetrics, and pediatric medical societies
American Society of Anesthesiologists (ASA)

The Society for Obstetric Anesthesia and Perinatology (SOAP),the American Society of Anesthesiologists (ASA), the Society for Pediatric Anesthesia (SPA) the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM) aim to clearly reassure pregnant women that the article “Association Between Epidural Analgesia During Labor and Risk of Autism Spectrum Disorders in Offspring,” a new retrospective database study published in JAMA Pediatrics on October 12th, 2020 does not provide credible scientific evidence that epidurals for pain relief cause autism.

8-Oct-2020 1:00 PM EDT
More young adults are abstaining from alcohol
University of Michigan

Fewer college-age Americans drink alcohol, compared to nearly 20 years ago, according to a new study.

Released: 9-Oct-2020 2:15 PM EDT
Young people hospitalized with COVID-19 face substantial adverse outcomes
Brigham and Women’s Hospital

While older age is widely recognized as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes.

Released: 9-Oct-2020 12:55 PM EDT
Weighing Risks and Benefits for Glaucoma Patients During COVID-19
Michigan Medicine - University of Michigan

Michigan Medicine ophthalmologists create a scalable algorithm for triaging appointments during the pandemic.

Released: 7-Oct-2020 5:20 PM EDT
Early COVID-19 Cases in Southern California Linked to New York
Cedars-Sinai

Most COVID-19 (coronavirus) patients in Southern California during the early months of the pandemic appear to have been infected by a variant of the SARS-CoV-2 virus introduced to the region from New York state via Europe, not directly from China, where the virus was first detected, according to a new study conducted at Cedars-Sinai.

5-Oct-2020 4:30 PM EDT
Yes or No: Forcing a Choice Increased Statin Prescribing for Heart Disease Patients
Perelman School of Medicine at the University of Pennsylvania

Adding an “active choice” nudge to the electronic health record increased statin prescribing for patients with heart disease, but not for those “at-risk”

Released: 6-Oct-2020 11:00 AM EDT
Story Tips From Johns Hopkins Experts On COVID-19
Johns Hopkins Medicine

Johns Hopkins Medicine biomedical engineering student Christopher Shallal developed an initiative to keep health care teams safe by galvanizing community members to use 3D printers to make face shields. His mentors on the project were Elizabeth Logsdon, Ph.D., and Warren Grayson, Ph.D.

Released: 5-Oct-2020 12:05 PM EDT
Exposure to Vitamin D in the Womb Might Minimize Risk of High Blood Pressure for Children Born to Mothers with Preeclampsia
Johns Hopkins Bloomberg School of Public Health

Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy—but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb.

30-Sep-2020 12:30 PM EDT
Study Highlights Shortcomings in Telemedicine Despite Large Increases in Remote Consults During Covid-19 Pandemic
Johns Hopkins Bloomberg School of Public Health

Despite increased use of telemedicine during the COVID-19 pandemic, Americans have had significantly fewer consultations with primary care doctors and markedly fewer assessments of common cardiac risk factors.

Released: 30-Sep-2020 6:25 PM EDT
Study reveals unnecessary stress testing performed prior to knee and hip replacement surgeries
University of Chicago Medical Center

A new study shows the overall rate of preoperative stress testing for hip and knee replacements has been decreasing consistently since 2006, but that many stress tests performed each year were unnecessary.

Released: 30-Sep-2020 12:55 PM EDT
Study supports airborne spread of COVID-19 indoors
JAMA - Journal of the American Medical Association

New research from the University of Georgia supports growing evidence for airborne transmission of COVID-19 in enclosed spaces.

   
28-Sep-2020 5:05 PM EDT
Hydroxychloroquine No More Effective Than Placebo in Preventing COVID-19
Perelman School of Medicine at the University of Pennsylvania

Clinical trial shows health care workers in contact with COVID-19 patients who took hydroxychloroquine each day did not reduce their rate of infection

Released: 29-Sep-2020 4:35 PM EDT
Study supports airborne spread of COVID-19 indoors
University of Georgia

New research from the University of Georgia supports growing evidence for airborne transmission of COVID-19 in enclosed spaces.

Released: 28-Sep-2020 12:05 PM EDT
Genetic Testing Cost Effective for Newly Diagnosed GIST
UC San Diego Health

UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.

24-Sep-2020 7:05 PM EDT
ACA reduced out-of-pocket health costs for families with kids, but they still need help
University of California, Los Angeles (UCLA), Health Sciences

The percentage of low- and middle-income families with children that had burdensome out-of-pocket health care costs fell following the 2014 implementation of the health insurance marketplaces and Medicaid expansion provisions of the Affordable Care Act, known widely as Obamacare,

Released: 24-Sep-2020 3:45 PM EDT
Age restrictions for handguns make little difference in homicides as US deals with ‘de facto availability’ of firearms
University of Washington

In the United States, individual state laws barring 18- to 20-year-olds from buying or possessing a handgun make little difference in the rate of homicides involving a gun by people in that age group, a new University of Washington studyhas found.

23-Sep-2020 9:40 AM EDT
Handheld Device Could Someday Provide Fast, Objective Method to Diagnose Concussions in Youth Athletes
Children's Hospital of Philadelphia

Building upon years of research, a new study has demonstrated how a specific assessment of the eye could someday help properly diagnosis and monitor concussions.

Released: 23-Sep-2020 12:05 PM EDT
Prenatal cannabis exposure associated with adverse outcomes during middle childhood
Washington University in St. Louis

Research from the Department of Psychological & Brain Sciences at Washington University in St. Louis shows prenatal cannabis exposure may impact child behavior later in life.

Released: 22-Sep-2020 3:10 PM EDT
Nearly 20 percent of americans don't have enough to eat
Pennington Biomedical Research Center

More than 18 percent of U.S. adults do not know whether they will have enough to eat from day to day, and the numbers are worse for Hispanics, Blacks, people with obesity, and women, a new report shows.

   
Released: 18-Sep-2020 4:05 PM EDT
Global first in mixed-reality education during COVID-19 pandemic
Case Western Reserve University

The developers of Case Western Reserve University’s signature HoloAnatomy mixed-reality software for the Microsoft HoloLens knew they were likely achieving a global first this Spring when they quickly pivoted to the first-ever, all-remote anatomy course when the COVID-19 pandemic kept 185 first-year medical students from coming to campus. Now, they have data reporting that an overwhelming majority of those students across the U.S. and Canada not only preferred the remote course, but believe they can effectively learn anatomy via the mixed-reality application.

16-Sep-2020 1:05 PM EDT
Daily coffee consumption associated with improved survival in patients with metastatic colorectal cancer
Dana-Farber Cancer Institute

In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and other organizations report in a new study.

Released: 16-Sep-2020 10:25 AM EDT
Potential COVID-19 drug azithromycin may increase risk for cardiac events
University of Illinois Chicago

Azithromycin — a commonly-prescribed antibiotic — also is being investigated as a potential treatment for COVID-19. Researchers have found that azithromycin by itself is not associated with an increase in cardiac events; however, if the drug is taken with certain other drugs that affect the electrical functioning of the heart, then cardiac events increased.

Released: 16-Sep-2020 9:00 AM EDT
Pollution Exposure Linked to Stroke Risk in People with Common Heart Rhythm Disorder
Health Sciences at the University of Pittsburgh

People with atrial fibrillation who are exposed to greater levels of pollution have a higher risk of stroke than their peers who live with less pollution.

Released: 14-Sep-2020 12:10 PM EDT
Doctors Get Plenty of Advice on Starting Treatment. This Could Help Them Know When to Stop.
Michigan Medicine - University of Michigan

Decades of effort have improved the chances that patients will get the scans, routine tests and medicines that can do them the most good – and avoid the ones that won’t help them at all. But in the push toward evidence-based medicine, a new study says, a key step has mostly gotten overlooked: helping doctors stop or scale back – or deintensify – treatment once it has started.

10-Sep-2020 8:05 PM EDT
Ohio State Study Shows Cardiac MRI Effective in Identifying Myocarditis in Athletes
Ohio State University Wexner Medical Center

A cardiac MRI is effective in identifying inflammation of the heart muscle in athletes and can help determine when those who have recovered from COVID-19 can safely return to play in competitive sports, according to a new study by researchers at The Ohio State University Wexner Medical Center.

9-Sep-2020 11:05 AM EDT
Study shows high blood pressure awareness and control are declining in America
University of Alabama at Birmingham

After nearly 15 years on an upward trend, awareness among Americans about their high blood pressure and rates of blood pressure control are now on the decline. many groups, including older adults and Black adults, are less likely than they were in earlier years to control their blood pressure.

Released: 8-Sep-2020 3:30 PM EDT
Generic Cholesterol Drugs Save Medicare Billions of Dollars, Study Finds
UT Southwestern Medical Center

DALLAS – Sept. 9, 2020 – The switch from brand name to generic cholesterol medications that occurred between 2014 and 2018 has saved Medicare billions of dollars, even as the number of people on cholesterol-lowering drugs has increased, UT Southwestern scientists have calculated. Their data, published in the journal JAMA Cardiology, suggest that policymakers and clinicians could help cut Medicare costs even further by switching more patients to generic drugs.

4-Sep-2020 2:05 PM EDT
Some Children at Higher Risk of Privacy Violations from Digital Apps
Michigan Medicine - University of Michigan

While federal privacy laws prohibit digital platforms from storing and sharing children’s personal information, those rules aren’t always enforced, researchers find.

Released: 3-Sep-2020 12:50 PM EDT
COVID has likely tripled depression rate: BU study
Boston University School of Medicine

A first-of-its-kind study from the Boston University School of Public Health (BUSPH) finds 27.8% of U.S. adults had depression symptoms as of mid-April, compared to 8.5% before the COVID-19 pandemic.

3-Sep-2020 7:05 AM EDT
Study: Vitamin D deficiency may raise risk of getting COVID-19
University of Chicago Medical Center

In a retrospective study of patients tested for COVID-19, researchers at the University of Chicago Medicine found an association between vitamin D deficiency and the likelihood of becoming infected with the coronavirus. The findings were published Sept. 3 in JAMA Network Open.

Released: 2-Sep-2020 5:55 PM EDT
Steroid found to improve survival of critically ill COVID-19 patients
Imperial College London

A new international study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery.

Released: 1-Sep-2020 6:35 PM EDT
Study: Anonymized cell phone location data can help monitor COVID-19 growth rates
Mount Auburn Hospital

In March 2020, federal officials declared the COVID-19 outbreak a national emergency. Around the same time, most states implemented stay-at-home advisories - to different degrees and at different times.

   
Released: 1-Sep-2020 6:10 PM EDT
Improving FDA's COVID-19 vaccine authorization and approval process
Dartmouth College

On March 28, the Food and Drug Administration (FDA) exercised its Emergency Use Authorization (EUA) authority to allow the use of hydroxychloroquine for the treatment of COVID-19.

Released: 1-Sep-2020 11:30 AM EDT
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Released: 31-Aug-2020 12:30 PM EDT
College students access eating disorders therapy via phone app
Washington University in St. Louis

Studying college women with eating disorders, a team led by researchers at Washington University School of Medicine in St. Louis found that a phone-based app that delivers a form of cognitive behavioral therapy was an effective means of intervention in addressing specific disorders.

27-Aug-2020 3:55 PM EDT
Cell Phone Location Used to Estimate COVID-19 Growth Rates
Perelman School of Medicine at the University of Pennsylvania

Data shows that coronavirus infection rates were lower in counties where cell phone activity declined at workplaces and increased at home

   
25-Aug-2020 1:00 PM EDT
Systematic Testing of Environmental Surfaces in a Radiation Oncology Clinic Shows no Detectable SARS-CoV2
Rutgers Cancer Institute of New Jersey

It has been hypothesized that SARS-CoV2 spread among people via droplets that come from the nose and mouth or through contact with contaminated objects and surfaces. Researchers at Rutgers Cancer Institute found that environmental surface testing at the center’s Radiation Oncology Department located within Robert Wood Johnson University Hospital, an RWJBarnabas Health facility, during the height of the COVID-19 pandemic in the state showed no detectable SARS-CoV2 – the virus that causes COVID-19.

26-Aug-2020 12:45 PM EDT
Cochlear implants should be recommended for adults more often
Washington University in St. Louis

An international group of hearing specialists has released a new set of recommendations emphasizing that cochlear implants should be offered to adults who have moderate to severe or worse hearing loss much more often than is the current practice. The group hopes the recommendations help increase usage of such devices, potentially improving hearing and quality of life for millions worldwide.

Released: 26-Aug-2020 1:20 PM EDT
Gunshot Injuries in California Drop, but Percentage of Firearm Deaths Goes Up
UC Davis Health (Defunct)

Despite a significant drop in gun injuries, California has experienced a substantial increase in the state’s overall death rate among those wounded by firearms.

24-Aug-2020 4:05 PM EDT
Largest pharmacogenetic clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy
Mayo Clinic

ROCHESTER, Minn. ― Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in cardiology, suggests that genetic testing could potentially be a useful tool to help select antiplatelet medication. Pharmacogenetics is the use of a patient's genetic makeup in prescribing treatments that are likely to be most successful.



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