According to a new study by Hospital for Special Surgery investigators presented at the American College of Rheumatology meeting Oct. 21, most lupus patients are not aware that their condition puts them at a higher risk for cardiovascular disease and a counseling program is a valuable way to promote education and lifestyle change.
People who suffer from both lupus and depression could experience additional health problems, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Philadelphia, Pa.
Insecticide exposure may increase the risk of developing two well known autoimmune rheumatic diseases in post-menopausal women, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Philadelphia, Pa.
Cigarette smoking leads to rheumatic disease and makes treatment less successful, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Philadelphia, Pa.
In patients with systemic lupus erythematosus, their race can affect how severe the disease will become, according to a new study.
Patients suffering with chronic autoimmune diseases from every corner of the globe can now find one another online to provide support, share experiences, and form relationships. The new Autoimmunity Forum launched by the American Autoimmune Related Diseases Association (AARDA) is a virtual support group community nearly 400 members strong.
A research team has generated DNA-like compounds that effectively inhibit the cells responsible for the most common and serious form of lupus. The findings could eventually lead to new treatments for this difficult disease, which affects up to one million Americans.
Lupus is a rare but serious disease that mainly affects women of child-bearing age and occurs when the body's immune system goes awry, damaging a variety of organs. When kidneys are targeted, patients develop lupus nephritis, which can result in kidney failure and death. Lupus nephritis is often treated with the cancer drug cyclophosphamide, which suppresses the immune system but also causes hair loss, nausea, vomiting, and infertility.
In an international human genetic study, researchers at UT Southwestern Medical Center have identified a gene linked to the autoimmune disease lupus, and its location on the X chromosome might help explain why females are 10 times more susceptible to the disease than males.
A recent study of 20 people suffering from lupus nephritis, a severe kidney disorder, who were all high risk cases for kidney failure, were given the cancer drug Rituxan. Of these patients, 60 percent showed significant signs of improvement. If this study can be replicated in larger numbers, it could translate into an FDA approval of Rituxan for lupus patients. If so, it would break a 50-year record of no new drugs having been approved by the U.S. Food and Health Administration specifically for lupus.
Treatment with the targeted drug rituximab can significantly benefit some patients with severe lupus nephritis who do not respond to conventional therapy, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The findings indicate that this immunosuppressive agent could improve the health of patients who have few other treatment options and who might otherwise develop end-stage renal disease.
Mice from a strain that ordinarily develops systemic lupus erythematosus (SLE), but bred with a deficiency in receptor for the protein Interleukin 21, stayed healthy and exhibited none of the symptoms of the disease, researchers at The Jackson Laboratory and National Institutes of Health report.
A gene discovered by scientists at Wake Forest University School of Medicine has been linked to lupus and related autoimmune diseases. The finding, reported online in Nature Genetics, is the latest in a series of revelations that shed new light on what goes wrong in human cells to cause the diseases.
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