Feature Channels: Cardiovascular Health

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The Dhillon family seemed to be living the California dream, enjoying the waterway just steps from their home on Naples Island. But a little more than five years ago, when their daughter, Daya, began feeling ill, the Dhillon family’s California dream morphed into a medical nightmare.

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The global study assessed risk factors, including metabolic (such as high blood pressure, obesity and diabetes), behavioural (smoking and diet), and psychosocial (economic status and depression) in about 156,000 people without a history of CVD between the ages of 35 and 70. Living in 21 low, middle and high-income countries on five continents, they were followed for an average of 10 years.

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After a rare disease caused organ failure, UC San Diego Heath transplant teams performed a heart, liver and kidney transplant on a patient. The surgery is a first for UC San Diego Health and a first in the nation to use three organs from a donor after circulatory death.

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Nebraska researchers seek to identify the bioactive molecules that give chive nanoparticles their "very strong anti-inflammatory function."

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Racial and ethnic minorities in Los Angeles County are more likely to live as far as or farther than five miles from a cardiac rehabilitation facility, according to a new study by investigators at the Smidt Heart Institute at Cedars-Sinai.

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The latest research and expert commentary on pain management.

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Researchers at the Georgia Institute of Technology and clinicians at Emory University School of Medicine are bringing a new understanding to these complicated conditions with the first high-resolution visualizations of stable spiral waves in human ventricles.

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Among several lifestyle changes that may reduce cardiovascular disease, adopting the DASH (Dietary Approaches to Stop Hypertension) diet may have the greatest impact for young and middle-aged adults with stage 1 hypertension, according to new research presented at the American Heart Association’s Hypertension Scientific Sessions 2022, held Sept. 7-10, 2022, in San Diego.

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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A series of upcoming studies will explore whether the grind of active-duty military life and veterans’ disproportionately high incidence of chronic illness could be tamed by lifestyle interventions designed to achieve a metabolic state of nutritional ketosis.

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Culinary medicine programs are emerging at medical schools to meet a critical need to improve nutrition education in an era of unprecedented diet-related health problems including obesity and cardiovascular disease, according to a review of programs by UT Southwestern researchers published in Academic Medicine, the journal of the Association of American Medical Colleges.

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Mice lacking Regnase-1 in myeloid cells spontaneously developed severe pulmonary arterial hypertension, mirroring the same pathology in humans. The decay of mRNA by Regnase-1 leads to PAH inhibition, suggesting its possible as a disease biomarker.

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A new study from Israel found that the risk of developing myocarditis among males ages 16 to 19 years was about 1 in 15,000 after third dose of the Pfizer-BioNTech COVID-19 vaccine, and the cases were rare and mild, according to new research published today in the American Heart Association’s flagship journal Circulation.

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Having easier access to primary care physicians may increase high blood pressure awareness and control regardless of where a person lives, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed journal of the American Heart Association.

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William Morice II, M.D., Ph.D., has been named CEO and president and Mary Jo Williamson has been named chief administrative officer of Mayo Clinic Laboratories and other diagnostic services in the biopharma and cardiovascular spaces. Mayo Clinic Laboratories is the reference laboratory for Mayo Clinic, providing health care professionals access to the world's most sophisticated test catalog and thousands of Mayo Clinic experts.

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妙佑医疗国际(Mayo Clinic)参与的一项首次人体多中心试验使用了一种新型消融技术来治疗室性心动过速患者。室性心动过速是一种心律异常加快的疾病，已成为全球心源性猝死病例的主要元凶之一。

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Ali Azizzadeh, MD, an internationally recognized vascular surgeon at Cedars-Sinai, has been appointed associate dean of Faculty Affairs.

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Um primeiro estudo multicêntrico em humanos envolvendo a Mayo Clinic usou uma nova técnica de ablação para pacientes com taquicardia ventricular (um ritmo cardíaco anormalmente rápido que é uma das principais causas de morte súbita cardíaca em todo o mundo).

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Un ensayo realizado por primera vez en seres humanos y en varios centros, entre los que está Mayo Clinic, empleó una nueva técnica de ablación para los pacientes con taquicardia ventricular, o ritmo cardíaco anormalmente rápido que es la causa principal de muerte cardíaca súbita en todo el mundo.

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Symptoms are subjective experiences that may indicate underlying cardiovascular disease or change therein and are of fundamental significance not only to the diagnosis of cardiovascular disease (CVD) and appraisal of response to medical therapy but also directly to patients’ daily lives.

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A 70-year-old man is recovering safely at Ochsner Medical Center—New Orleans following a dramatic resuscitation by an Ochsner Health cardiologist that friends and family describe as “divine intervention.”

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A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

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An unexplained case of severe coronary artery disease in a seemingly healthy young man led scientists at The Ohio State University Wexner Medical Center and College of Medicine to a discovery that could lead to a new way to treat high cholesterol.

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Research could lead to potential new ways to prevent strokes in young adults.

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Gene variants associated with a person’s blood type may be linked to their risk of early stroke, according to a new meta-analysis published in the August 31, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. The meta-analysis included all available data from genetic studies that included young adult ischemic stroke, which is caused by a blockage of blood flow to the brain.

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The latest research on plants brought to you by Newswise.

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New research from the Smidt Heart Institute at Cedars-Sinai demonstrated that women—when height is accounted for—have a 50% higher risk of developing the abnormal heart rhythm disturbance when compared to men.

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Among people older than age 65 who were assessed using a short physical function test, having lower physical function was independently associated with a greater risk of developing heart attack, heart failure and stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

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Mount Sinai study could lead to ongoing health monitoring of astronauts to assess possible health risks and prevent disease progression

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In Biophysics Reviews, researchers explore how human tissue models can be used to examine the impact of heart attacks and treatment of the fibrotic tissue outside the body, improving treatment and diagnosis. They use organoids, 3D organlike multicellular models derived from stem cells, to mimic natural development, structural organization, regeneration, and disease progression. Meanwhile, microfluidic devices control cell placement and fluid flow to act like the heart on a chip, while bioprinting allows cardiac tissue to be built up layer by layer.

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In the Journal of Applied Physics, researchers develop a method to identify aortic valve dysfunction using complex network analysis that is accurate, simple to use, and low-cost. They used heart sound data to create a complex network of connected points, which was split into sections, and each part was represented with a node. If the sound in two portions was similar, a line was drawn between them. In a healthy heart, the graph showed two distinct clusters of points, with many nodes unconnected. A heart with aortic stenosis contained many more correlations and edges.

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The National Comprehensive Cancer Network’s Oncology Research Program is collaborating with Pfizer and Myovant to address cardiovascular risk in patients with prostate cancer being treated with androgen deprivation therapy (ADT).

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During National Atrial Fibrillation (AFib) Awareness Month and Aortic Disease Awareness Week, Smidt Heart Institute cardiologists and surgeons are available for interviews with journalists working on stories about these common heart conditions.

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A six-year analysis of more than 94,000 adults in the U.K. Biobank with no history of heart failure at enrollment has found that engaging in moderate or vigorous physical activity may lower the risk of developing heart failure, according to new research published today in the American Heart Association’s flagship journal Circulation.

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A new type of extravascular implantable cardioverter-defibrillator (ICD) using a lead (thin wire) placed behind the sternum met safety and effectiveness goals for participants in a premarket global clinical study. The device effectively terminated acute and chronic life-threatening ventricular arrhythmias. The findings were presented during a late-breaking session at the European Society of Cardiology Congress and were simultaneously published in The New England Journal of Medicine.

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All too often, patients go to the ER complaining of unexplained chest pain. After a battery of tests show no evidence of blocked heart arteries, the patients are sent home. Then, they return to the ER with the same symptoms. Until now. MedStar Heart & Vascular Institute is one of the few programs in the nation to have the innovative tool to find the culprit: coronary microvascular dysfunction, or CMD, a condition in which the heart’s tiniest arteries don’t dilate properly.