A software tool to automatically calculate how extensively bones have been infiltrated by prostate cancer is both accurate and speedy, capturing key prognostic information related to survival and the development of symptoms over time.
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
A meditation and stress reduction program may be as effective at getting people to move as structured exercise programs, according to a study led by an Iowa State researcher. Jacob Meyer is part of another study that found resistance training reduces symptoms of depression.
Researchers from the Smith Center for Outcomes Research in Cardiology at Beth Israel Deaconess Medical Center (BIDMC) provide a closer look at physicians’ knowledge, attitudes and beliefs about PCI public reporting.
Very few depression patients receive the treatment once known as ‘shock therapy’. But a new cost-effectiveness study suggests that the modern form of the approach, called ECT, should be made more available to patients who fail to get relief from two other types of treatment.
When the Centers for Medicare and Medicaid Services (CMS) announced controversial policies inviting states to establish work requirements as a condition to receive Medicaid, many in the medical community opposed it. If these measures continue to be approved – as is the case in Kentucky, Indiana, and Arkansas – CMS should act to minimize the potential harms they could cause to Medicaid recipients, two Penn Medicine experts in law and ethics argue in a new JAMA Viewpoint published this week, that lays out basic safeguards to help guide the states. “Promoting health, after all,” the authors note, “is the goal of Medicaid.”
The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
Eye inflammation and uveal effusion develop among patients taking anti-cancer immune checkpoint inhibitor therapy.
Researchers at Memorial Sloan Kettering (MSK) report that firefighters at the World Trade Center (WTC) scene in September 2001 were nearly twice as likely as the general population to have a multiple myeloma precursor condition called monoclonal gammopathy of undetermined significance (MGUS).
Effect is greatest among those with highest illness burden
They cost thousands of dollars, and insurance almost never covers them. But hearing aids may hold the potential to cut older adults’ visits to the hospital or emergency room, according to a new study. That could mean lower costs in the long run, though more research is needed to see if this is true. The study arrives at a time when discussion about adding Medicare coverage for hearing aids is rising.
Research led by UNC School of Medicine student Wesley Stepp, PhD, shows how more detailed genetic testing of head and neck tumors could lead to more personalized treatments for patients.
Study shows potential link between Parkinson’s disease and inflammatory bowel disease, suggests anti-TNFα therapy may reduce the risk of developing Parkinson’s disease
Soldiers who deploy twice in one year, with six months or less between each deployment, could be at an increased risk for attempted suicide during or after their second deployment, according to a study published April 18.
PAs increasingly used in dermatology to cut costs and improve access, but are less likely than dermatologists to accurately diagnose early stage skin cancers, according to new research.
Are indoor tanners taking measures to prevent skin cancer? A researcher from Rutgers Cancer Institute of New Jersey and colleagues at Fox Chase Cancer Center found a majority of the indoor tanners analyzed in this study are not taking part in skin cancer screening.
Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas MD Anderson Cancer Center. The preclinical research challenges traditional models of cancer immune activation and suggests immunotherapy may be useful for colorectal cancer prevention in certain high-risk groups.
Studying data from more than 125,000 individuals, an international team of researchers led by scientists at Washington University School of Medicine in St. Louis has identified genetic links between amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. The link between the seemingly unrelated disorders suggests that some drugs developed to treat ALS also may work against frontotemporal dementia and vice versa.
A new smartphone app allows Parkinson's disease patients and their doctors to better track the progression of symptoms, such as tremors and walking difficulties, that can vary dramatically over days, or even hours.
People have a 50 percent higher risk of death if they suffer a shocking financial loss
超过一半的美国医生表示他们在工作中曾经有过度劳累的问题。 今天，Mayo Clinic和其他领先的医疗中心发表了“医生健康章程”，作为医疗机构的一个 预期模型不仅要最大限度地减少和管理医生的劳累过度，而且还要促进医生的健康福利。 《美国医学会杂志》（JAMA）在线发表了该章程。该章程已经得到许多主要医疗机构（包括美国医学协会和美国医学院协会）的赞成或支持。
MRIs show that babies with fragile X syndrome had less-developed white matter compared to infants that did not develop the condition. Imaging various sections of white matter from different angles can help researchers focus on the brain circuitry important for proper neuron communication.
Hospital payment experiment in Maryland failed to deliver on the promise of shifting care from hospitals toward less expensive outpatient and primary care settings. Researchers say that weak incentives for physicians may have limited the program’s effectiveness.
Más del 50 por ciento de los médicos en Estados Unidos dicen sentir agotamiento en su trabajo. Por ello, Mayo Clinic y otros centros médicos principales publicaron hoy una “carta estatutaria para el bienestar de los médicos.”
Exposing infants to antacids or antibiotics in their first six months of life could increase their risk of developing allergies in childhood.
More than half of U.S. physicians say they experience burnout in their work. Today, Mayo Clinic and other leading medical centers have published a “Charter on Physician Well-Being” as an intended model for medical organizations to not only minimize and manage physician burnout, but also promote physician well-being. The charter, which has been endorsed or supported by many major medical organizations, including the American Medical Association and the American Association of Medical Colleges, appears online in JAMA.
Chemotherapy agents have been associated with neurocognitive side effects in young leukemia survivors. Now St. Jude Children’s Research Hospital scientists have evidence the disease and genetics might also play a role.
Framework and Principles on Well-Being Aim to Benefit Patients and Strengthen Health Care Systems
After years of public health efforts, health care at the Los Angeles County Jail has significantly improved, and the facility now typically provides full access to treatment for inmates who have HIV — including medications that keep their disease in check. When they are released, however, many former inmates stop making regular visits to a doctor and taking the medication they need, which puts their own health at risk and increases the chance they will transmit the virus to others.
Receptivity to advertising for e-cigarettes, cigarettes and cigars were confirmed to be associated with those who would try the respective tobacco product within one year. However, receptivity to e-cigarette advertising also independently increased the odds that 12- to 21-year-olds who have never smoked would try cigarette smoking within the next year by 60 percent. This finding, publishing in the March 26 issue of JAMA Pediatrics, was independent of receptivity to cigarette advertising.
While there are many treatment options for men with prostate cancer, a recent national study published in JAMA compared the effectiveness of treatments for high-risk prostate cancer.
A decade ago, the late Seattle Children’s surgeon, Dr. Richard Grady, began traveling to India to provide urgent surgical care to children with a complex disorder called bladder exstrophy. An article in JAMA Surgery documents Grady's work through an international collaborative aimed at alleviating the global burden of this treatable disease.
A new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment. The analysis, which included 104 radiation therapy oncology groups across North America, was led by researchers at Washington University School of Medicine in St. Louis.
High drug prices as well as the excessive use of imaging and surgical procedures, and excessive administrative burdens contribute the majority to America’s health care overspending compared to Europe, argues policy expert Ezekiel J. Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medicine at the University of Pennsylvania, in an editorial in this week’s JAMA.
A new study from University of Michigan Kellogg Eye Center links familial relationships to the likelihood older adults will get needed cataract surgery — a procedure with broad implications for health.
Aseem R. Shukla, MD, a pediatric urologist at Children’s Hospital of Philadelphia, along with several of his colleagues from around the world, have created an innovative program to help address urological needs in India. The team is specifically addressing bladder exstrophy, a complex, rare disorder that occurs during fetal development when the bladder does not form completely and drains onto the surface of the abdomen.
Mount Sinai researchers have shown, for the first time, the complex web of links between physical and behavioral characteristics, like age, body mass index (BMI), and substance use, and specific patterns of brain structure and function in patients with psychosis. The study is important because many of these characteristics can be targeted clinically to improve brain health in these patients.
Medicare’s experimental mandatory bundled payment model for knee and hip replacements is more likely to yield cost savings when the surgeries are performed in larger hospitals that do more of these procedures, according to a study from the Perelman School of Medicine at the University of Pennsylvania. Non-profit and major teaching hospital status also appear to be associated with cost savings, the Penn Medicine analysis found.
In a collaborative, multi-institutional study published by JAMA Oncology, researchers from the University of Alabama at Birmingham, University of Chicago, and National Cancer Institute determined that MRI-based prediction models can help reduce unnecessary biopsies in suspected prostate cancer patients and help improve personalized risk stratification.
A sizable percentage of elderly patients with blood-related cancers such as leukemia and multiple myeloma are apt to show signs of diminished cognitive functioning
Women who have one or both breasts removed to treat cancer may have unrealistic expectations about how they’ll feel after that surgery and after breast reconstruction, if they choose that option, a U.S. study suggests. Newsmax Article
A new study debunks the “obesity paradox,” a counterintuitive finding that showed people who have been diagnosed with cardiovascular disease live longer if they are overweight or obese compared with people who are normal weight at the time of diagnosis.
Rutgers and Stanford researchers develop new mathematical model to explain how smartphones act as “portable funhouse mirrors”
In a national medical records analysis, researchers at Johns Hopkins Medicine say there is evidence that the number of gender affirming surgeries performed in hospitals for transgender individuals is on the rise, along with increased access made possible by Medicare, Medicaid or private insurance coverage for the procedures.
Signing up for 5Ks and even a 10K is a feat many people with hypertrophic cardiomyopathy may not have dared to attempt a decade or two ago. Fear of tragedy leads many HCM patients to a sedentary lifestyle.
Long-term acute care (LTAC) facilities are designed to meet the needs of older adults with severe, complex illnesses who are recovering from hospitalization, but less expensive options sometimes overlooked may also be available, population health researchers at UT Southwestern found.
UCLA researchers found that nearly all people diagnosed with uveal melanoma had a number of unmet psychological and health information needs, particularly during the first three months after their diagnoses. The study is the first prospective, longitudinal approach to examine supportive care needs among patients with this disease, and suggested more acute needs among people with uveal melanoma than people with other cancers.
A comprehensive evaluation by clinical researchers at the Perelman School of Medicine at the University of Pennsylvania identified a neurological syndrome that left U.S. government personnel serving in Havana, Cuba with persistent memory and thinking dysfunction, as well as vision and balance problems after hearing unusual noises in their homes or hotel rooms. The team published their findings today in JAMA.
Family history of breast cancer continues to significantly increase chances of developing invasive breast tumors in aging women — those ages 65 and older, according to research published in JAMA Internal Medicine. The findings could impact mammography screening decisions later in life.
Comparison of two of the most commonly prescribed drugs for infants with nonsyndromic epilepsy revealed that levetiracetam was more effective than phenobarbital, according a multicenter, observational study published in JAMA Pediatrics. After six months of single-drug treatment, 40 percent of infants who received levetiracetam met criteria for successful outcome – they did not require a second anti-epileptic drug to control their seizures and they became seizure-free within three months of starting treatment. Only 16 percent of infants treated with phenobarbital achieved the same outcome.
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