The detection of prions in the blood of patients with variant Creutzfeldt-Jakob disease could lead to a noninvasive diagnosis prior to symptoms and a way to identify prion contamination of the donated blood supply, according to researchers at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth).
Health and wellness tips about preventing blood shortages, cardiorespiratory fitness check-up, and avoid holiday heart syndrome.
Modeling blood flow through a stent graft put graduate student John Asiruwa on the path to a career in biomedical engineering, doing work that “can be life changing for patients.”
Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels and reduces body fat in an animal model.
Researchers found that patients whose oropharyngeal cancer recurred had higher levels of antibodies for two proteins, E6 and E7, which are found in HPV-fueled cancers. The finding suggests a potential blood-based marker that could predict when cancer is likely to return.
Researchers have found that a Chinese herbal regimen called TSY-1 (Tianshengyuan-1) TSY-1 increased Telomerase activity in normal blood cells but decreased it in cancer cells. Telomerase is an enzyme responsible for the production of telomeres, which play an important role in the regulation of normal cell division. These results indicate that Telomerase-based treatments may be of significance in treatments for both blood cell deficiency and cancer.
Memorial Sloan Kettering Cancer Center and Hackensack Meridian Health announced the Memorial Sloan Kettering–Hackensack Meridian Health partnership, a joint venture that will combine both organizations’ unparalleled expertise in all areas of cancer care and research to accelerate new discoveries and improve the lives of patients they jointly serve.
This Saturday [Dec 3], the 58th Annual Meeting of the American Society of Hematology will begin in San Diego, where the latest advances in research for blood cancers including leukemia, lymphoma, and myeloma will be highlighted during the four days of talks and poster presentations.
Johns Hopkins researchers report that implementing a checklist-style set of procedures appears to cut almost in half the number of potentially unnecessary blood culture draws in critically ill children without endangering doctors' ability to diagnose and treat life-threatening blood infections.
Two new studies out of Case Western Reserve University School of Medicine describe how the inflammatory response to psoriasis can alter levels of several immune system molecules, ultimately increasing a person’s risk of thrombosis, which can include fatal blood clots
University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) to support a ground-breaking new study to investigate the effectiveness of giving patients blood products immediately after a major injury or trauma - before they reach hospital.
A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center (BIDMC). The product of a long-term collaboration among investigators at the Cancer Center at BIDMC and Dana-Farber Cancer Institute, the vaccine stimulated powerful immune responses against AML cells and resulted in protection from relapse in a majority of patients, the team of researchers reported today in Science Translational Medicine.
Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets. The initial laboratory tests at Empa in St. Gallen have been successful, and seem promising.
The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds. An interdisciplinary team of researchers from the Vanderbilt Institute for Integrative Biosystems Research and Education (VIIBRE) headed by Gordon A.
University of Alabama researchers are recruiting for a 10-week study to see how watermelon impacts blood vessel function.
Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. In a report on the work, published online in the journal Circulation on Nov. 30, the team says a large class of common blood pressure drugs that target the angiotensin receptor, called angiotensin receptor blockers (ARBs), may help patients depending on the levels of the autoantibodies.
Analysis of a phase 3 trial shows that older patients with high-risk or secondary AML, who received initial treatment with CPX-351, had improved survival following allogeneic hematopoietic cell transplant, when compared with patients who received standard 7+3 cytarabine and daunorubicin as initial therapy.
Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia. Many patients with lower-risk MDS benefit from treatment with recombinant-erythropoietin (rHuEPO), which stimulates blood cell production.
As the Zika epidemic spreads to the United States, the potential for contracting the disease via blood transfusion has emerged as a serious concern. The problem of transfusion-related Zika virus transmission—and recommended strategies to reduce that risk—are outlined in a special article in Anesthesia & Analgesia. Anesthesia & Analgesia is published by Wolters Kluwer.
A ruptured abdominal aortic aneurysm is the 15th leading cause of death in the country, and the 10th leading cause of death in men older than 55.
Whether patients with mechanical heart valves or left ventricular assist devices must take blood thinners depends on how effectively blood flows through these implantable devices. Researchers have modeled the flow of blood through these devices to estimate clotting risk, but this type of work has not been done on stent grafts—until now. The results showed that shear accumulation in a new endovascular stent graft design was comparable to that of an idealized aorta.
• New research estimates the projected lives that would be saved if patients at high risk of cardiovascular disease underwent intensive blood pressure lowering. • The findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.
Carrying extra weight increases a person's risk that a benign blood disorder will develop into multiple myeloma, a blood cancer. This is particularly true for older, African-American men.
Roughly 86 million Americans have prediabetes, and the vast majority of them don’t even know they have it. But the progression from prediabetes to type 2 diabetes is not inevitable, and there’s a simple blood test that can determine whether a person’s blood glucose levels need attention.
Freezing and reanimating your body is still science fiction, but cryopreserving cells and certain tissues for future use is a reality. Still, the process could use some improvements to make it more useful in emergencies. In a recent study in the journal ACS Omega, scientists take a close look at a new class of small molecules with the potential to make the process more practical and give the cells and tissues a longer shelf life.
A new study led by scientists at The Scripps Research Institute (TSRI) reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch.
The latest research and features on obesity in the Obesity News Source.
A new treatment may diminish a dangerous side effect associated with transfusions of red blood cells (RBCs) known as pulmonary hypertension, an elevated blood pressure in the lungs and heart that can lead to heart failure, suggests a new study published in the November issue of Anesthesiology.
Zinc is essential for wound healing, for vision, for DNA creation, for our senses of taste and smell, even for sexual health. But despite its importance, scientists have never fully understood the mechanism that moves the mineral through the body – until now. Researchers have, for the first time, created detailed blueprints of the molecular moving vans that ferry this important mineral everywhere it’s needed through the blood.
A half billion dollars – at least -- gets spent each year on blood tests to see which hospital patients have a genetic quirk that makes their blood more likely to form dangerous clots. And most of that spending probably isn’t necessary, a new review shows.
Incapacitating specific nerves to the kidneys improves the work of insulin on another organ, the liver, according to research from Cedars-Sinai recently published in the journal Diabetes.
Researchers with the UCI Susan Samueli Center for Integrative Medicine have found that regular electroacupunture treatment can lower hypertension by increasing the release of a kind of opioid in the brainstem region that controls blood pressure.
A newly published study of people with chronic obstructive pulmonary disease (COPD) concludes that long-term supplemental oxygen treatment results in little or no change in time to death, time to first hospitalizations or significant quality of life improvements for those with moderately low blood oxygen levels.
The Canadian Patent Office awarded Streck a patent regarding its Cell-Free DNA BCT®, a direct-draw blood collection tube that stabilizes nucleated blood cells. Streck received patent #2,690,651 on October 4, 2016. The patent relates to the use of Streck’s proprietary Cell-Free DNA BCT product for the collection of samples to analyze fetal nucleic acid.
The Latest in Cell Biology News
ROCHESTER, Minn. – People diagnosed with multiple myeloma are more likely to live longer if they are treated at a medical center that sees many patients with this blood cancer. Mayo Clinic researchers published these findings today in the Journal of Clinical Oncology.
High blood pressure in middle age can lead to impaired cognition and is a potential risk factor for Alzheimer’s disease.
St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project team identifies genetic changes underlying a type of B-precursor acute lymphoblastic leukemia
It’s been long thought that when blood transfusions are needed, it may be best to use the freshest blood, but McMaster University researchers have led a large international study proving that it is not so.
In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier.
Hematology researchers have found that blocking the role of a common protein may offer unexpected benefits for patients with the inherited bleeding disorder hemophilia A. The finding offers potential for developing both gene therapy and more effective protein replacement treatments for hemophilia A, the most common form of hemophilia.
joint research published today in Nature Communications has shown new molecular causes of brain cancer and leukemia.
A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients. For the first time, they have corrected the mutation in a proportion of stem cells that is high enough to produce a substantial benefit in sickle cell patients.
For most stable hospitalized patients, transfusions of red blood cells stored for any time point within their licensed dating period — so-called standard issue — are as safe as transfusions with blood stored 10 days or less, or “fresh,” according to updated clinical guidelines issued by an expert panel convened by a national organization that has long set standards for blood banking and transfusion practices.
Most patients who need blood transfusions – including those who are critically ill – can be given blood when their hemoglobin drops to a lower level than practiced traditionally, according to AABB, a national association of blood banks that based its recommendation on research led by Rutgers University.
Seven-year-old Rey Ahumada should be jumping and playing outside like most other children his age. Instead, he’s fighting leukemia and “stuck in a bubble,” says his mom, an admissions clerk at UCLA Medical Center, Santa Monica. “That word, ‘cancer,’” she adds. “We need to put an end to it.” With that as a goal, UCLA Health is presenting sponsor of the Leukemia & Lymphoma Society’s Oct. 22 “Light the Night Walk” in Los Angeles. Jassmine will be carrying a red lantern in support of Rey and other patients with blood cancers who are hoping for a cure. Individuals who wish to commemorate a loved one lost to cancer will carry yellow lanterns, while cancer survivors will carry white, signifying the power of research.
In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice. The findings create a new pathway for study into the cause of MF and provide new therapeutic targets to block the progression of this rare form of blood cancer.
SEATTLE – (Sept. 20, 2016) – Seattle Cancer Care Alliance (SCCA) has opened a new Prostate Cancer Genetics Clinic at their South Lake Union campus in Seattle. The specialty clinic will serve patients with prostate cancer that has spread beyond the prostate (metastatic) and/or who have a family history of the disease or a family history of breast cancer, ovarian cancer, pancreatic cancer, lymphoma or leukemia. These men are more likely to have an inherited and more aggressive form of prostate cancer. Knowing a patient has a particular genetic mutation helps doctors choose the best treatment plan and can open doors for innovative clinical trials.
In the study published in the Journal of Clinical Oncology, UNC Lineberger researchers report that nearly a third of a group of patients with chronic myeloid leukemia, and who have federally-funded Medicare health insurance, did not start treatment within six months of diagnosis with any of three targeted drugs that have led to dramatic improvements in survival for the disease.
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