Patients with age-related macular degeneration (AMD), the most common cause of major vision loss in older people, still show benefits from a new class of therapy -- originally developed to treat cancer -- after long-term treatment.
Frailty, a condition that affects 10 percent of people aged 65 and older, can make older adults more prone to disability, falls, hospitalization and a shorter lifespan. Recently, researchers writing in the Journal of the American Geriatrics Society examined the effects of frailty and depression on married couples. Although we know much about the effects of frailty and depression on individuals, up until now, little has been uncovered about how these two conditions may be connected within couples.
Researchers writing in the Journal of the American Geriatrics Society recently learned that older women who are frail, and who have six or more chronic health conditions, are twice as likely to have a lower quality of life compared to women with less than three risk factors.
A Stanford-led national collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ’s function changes as we age, and could point the way toward new diabetes treatments.
Events will address challenges for older adults, children, LGBT population and minority boys and men.
Falls are one of the leading causes of injury-related death among elderly people. So finding the risk factors that endanger them is becoming increasingly important, particularly with the projected increase in the elderly population with the baby boomers.
Probiotic supplements protected female mice from the loss of bone density that occurs after having their ovaries removed, researchers at Emory University School of Medicine and Georgia State University have shown.
Researchers at UB's Research Institute on Addictions have discovered how a gene in the brain’s dopamine system can play an important role in prolonging lifespan: it must be coupled with a healthy environment that includes exercise.
• Systolic blood pressure levels above 140 mmHg were linked with higher risks of coronary heart disease, stroke, kidney failure, and death in patients with chronic kidney disease of all ages, but the magnitude of these associations diminished with more advanced age. • Diastolic blood pressure levels below 70 mmHg were associated with a higher risk of death, but otherwise they showed no association with cardiovascular outcomes
Long before Alzheimer’s disease can be diagnosed clinically, increasing difficulties building cognitive maps of new surroundings may herald the eventual clinical onset of the disorder, finds new research from Washington University in St. Louis.“These findings suggest that navigational tasks designed to assess a cognitive mapping strategy could represent a powerful new tool for detecting the very earliest Alzheimer’s disease-related changes in cognition,” said senior author Denise Head, associate professor of psychological and brain sciences in Arts & Sciences.
An eight-year-long accrual and analysis of the whole genome sequences of healthy elderly people, or “Wellderly,” has revealed a higher-than-normal presence of genetic variants offering protection from cognitive decline, researchers from the Scripps Translation Science Institute reported.
It has been disorienting to the scientific and medical community as to why different subtle changes in a protein-coding gene causes many different genetic disorders in different patients -- including premature aging, nerve problems, heart problems and muscle problems. no other gene works like this. According to a new study, co-authored by Binghamton University faculty Eric Hoffman, it has to do with cell “commitment.”
Among adults 60 years of age or more, walking is the most common form of leisure-time physical activity because it is self-paced, low impact and does not require equipment. Researchers at the University of Missouri have determined that older adults who also are pet owners benefit from the bonds they form with their canine companions.
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Older adults who met twice-weekly strength training guidelines had lower odds of dying in a new analysis by researchers at Penn State College of Medicine, Penn State Health Milton S. Hershey Medical Center and Columbia University.
Whether a creature is a worm, a fly, a mouse, or a human, death inevitably awaits. And not only do these organisms share a common fate, but also, according to a new study, they may share some of the specific mechanisms of mortality. The researchers found that in all four species, there are 46 genes regulated by the same family of "FOXO" proteins known to be central in aging and longevity.
A compound enriched in citrus peels strengthens the body clock and protects against metabolic syndrome in mice, according to a study led by scientists at The University of Texas Health Science Center at Houston (UTHealth).
Tested in both mice and human cells and produced in the energy-producing mitochondria of cells, the proteins may lead to greater understanding of aging-related diseases from diabetes to Alzheimer's to cancer.
Researchers at the University of California, San Diego School of Medicine have developed a novel method for assessing mortality risk in elderly patients with cancer who also suffer from other serious diseases or conditions. The prognostic model, they say, is more precise and provides a more useful tool for determining the best treatments when more than one disease is involved.
Researchers at Basel University Hospital in Switzerland investigate the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.
Kelly Mills, a finalist in the SSHRC Storyteller's challenge, tells the tale of her work with the Memory Writers, a remarkable group that has been writing and sharing stories with each other for more than 25 years.
Mobility is a major issue for older adults, and Wake Forest Baptist Medical Center researchers are working with colleagues across the country to help keep seniors on their feet.
An international team of scientists led by The Wistar Institute have shown that aged tumor cells in melanoma behave differently than younger tumor cells, according to study results published in the journal Nature. Changes in the microenvironment make these older tumor cells more metastatic and more resistant to treatment with targeted therapies.
Researchers at University of California, San Diego School of Medicine and University of British Columbia (UBC) have determined that, in mice, age diminishes ability to regenerate axons, the brain’s communication wires in the spinal cord. The study is published March 31 in Cell Reports.
New research suggests that looking at structures in the right side of the brain may help predict who will better recover from language problems after a stroke, according to a study published in Neurology®, a medical journal of the American Academy of Neurology.
A University of Guelph professor has uncovered the “secret” to staying strong as we age – superb fitness. Geoff Power found elderly people who were elite athletes in their youth or later in life – and who still compete as masters athletes — have much healthier muscles at the cellular level compared to those of non-athletes.
For most people, the culmination of a good life is a “good death,” though what that means exactly is a matter of considerable consternation. Researchers at the University of California, San Diego School of Medicine surveyed published, English-language, peer-reviewed reports of qualitative and quantitative studies defining a “good death,” ultimately identifying 11 core themes associated with dying well.
To understand how people can live longer throughout the world, researchers at University of California, San Diego School of Medicine have teamed up with colleagues at University of Rome La Sapienza to study a group of 300 citizens, all over 100 years old, living in a remote Italian village nestled between the ocean and mountains on the country’s coast.
Assistant professor Javier Apfeld plumbs the cellular mechanisms driving the aging process in worms, uncovering insights that could increase our own longevity.
Exercise in older people is associated with a slower rate of decline in thinking skills that occurs with aging. People who reported light to no exercise experienced a decline equal to 10 more years of aging as compared to people who reported moderate to intense exercise, according to a population-based observational study published in the March 23, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cell’s protein factory may hold key to stalling cognitive decline.
When it comes to aging, the focus is not just on living longer, quality of life is equally important. According to the National Institute on Aging, people aged 50 and older need more of some vitamins and minerals than younger adults do. In the March issue of Food Technology magazine published by the Institute of Food Technologists (IFT), Linda Mila Ohr wrote about 8 essential nutritional ingredients that can help aging individuals maintain an active lifestyle.
Imagine telling a patient suffering from age-related (type-II) osteoporosis that a single injection of stem cells could restore their normal bone structure. This week, with a publication in STEM CELLS Translational Medicine, a group of researchers from the University of Toronto and The Ottawa Hospital suggest that this scenario may not be too far away.
A new study published in Physiological Genomics suggests that the brain shows signs of aging earlier than old age. The study found that the microglia cells—the immune cells of the brain—in middle-aged mice already showed altered activity seen in microglia from older mice.
Could an unhealthy diet and lack of exercise be making you age faster? Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice. Results appear today in Diabetes.
A new study published may have uncovered the fountain of youth: plant extracts containing the six best groups of anti-aging molecules ever seen.
Study finds that retirement leads to positive lifestyle changes.
A study from two Texas Tech professors shows an alarming decrease in financial awareness among Americans of retirement age.
More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.
A new study shows that the more flights of stairs a person climbs, and the more years of school a person completes, the “younger” their brain physically appears.
A new study reveals that individuals in their 60s who give advice to a broad range of people tend to see their lives as especially meaningful. At the same time, this happens to be the age when opportunities for dispensing advice become increasingly scarce.
Nutrition scientists from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston with support from AARP Foundation are introducing an updated MyPlate for Older Adults icon to help older adults develop and maintain healthy eating patterns.
Keeping the brain active with social activities and using a computer may help older adults reduce their risk of developing memory and thinking problems, according to a study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.
The process of ageing begins even before we are born, according to an international team of researchers led by the University of Cambridge. In a study using rats to model pregnancy and fetal development, the researchers also found that providing mothers with antioxidants during pregnancy meant that their offspring aged more slowly in adulthood.
Sleep may be one of the most important factors for well-being; yet, according to the CDC, one in three adults does not get enough. Lack of sleep can lead to potential cognitive declines, chronic diseases and death. Now, research from the University of Missouri finds that older adults who have trouble sleeping, could benefit from participating in social activities, in particular attending religious events.
The blueberry, already labeled a “super fruit” for its power to potentially lower the risk of heart disease and cancer, also could be another weapon in the war against Alzheimer’s disease. The researchers present their work today at the 251st National Meeting & Exposition of the American Chemical Society.
Growing up in poverty or being abused by parents can lead to accumulated health problems later in life, according to research from Purdue University.
Homeless people in their fifties have more geriatric conditions than those living in homes who are decades older, according to researchers at UC San Francisco who are following 350 people who are homeless and aged 50 and over, in Oakland.
Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.
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