Researchers at the University of Liège (ULiège) have identified microstructures in fossil cells that are 1.75 billion years old. These structures, called thylakoid membranes, are the oldest ever discovered.
Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and the Boston University Sargent College of Health & Rehabilitation Sciences have used a soft, wearable robot to help a person living with Parkinson’s walk without freezing.
These “picosprings” have remarkably large and tuneable compliancy and can be controlled remotely through magnetic fields (even deep within the human body) allowing articulated motion in microrobots as well as micromanipulations well beyond the state of the art.
An international team of researchers, led by Professor Gustavo Goldman of the University of São Paulo and Maynooth University’s Dr Özgür Bayram, has unveiled ground-breaking findings on Aspergillus fumigatus, which can cause deadly disease in humans.
Irvine, Calif., Jan 4, 2024 — With a split-second muscle contraction, the greater blue-ringed octopus can change the size and color of the namesake patterns on its skin for purposes of deception, camouflage and signaling.
With help from an artificial language network, MIT neuroscientists have discovered what kind of sentences are most likely to fire up the brain’s key language processing centers.
A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King’s College London, Guy’s and St Thomas’ Hospital Trust, and the Francis Crick Institute have found.
Disease-causing bacteria of the genus Salmonella or Yersinia can use tiny injection apparatuses to inject harmful proteins into host cells, much to the discomfort of the infected person.
Like mail carriers who manage to deliver their parcels through snow, rain, heat and gloom, a critical group of mammalian proteins helps cells function properly even under less-than-ideal conditions.Using state-of-the-art cell imaging and genome editing technology, University of Wisconsin–Madison scientists have begun to unravel how this collection of proteins performs its essential service.
Researchers at the Georgia Institute of Technology have created the world’s first functional semiconductor made from graphene, a single sheet of carbon atoms held together by the strongest bonds known. The breakthrough throws open the door to a new way of doing electronics. Video summary: https://www.youtube.com/watch?v=gWUX2OTqkEo
Mount Sinai researchers have shown for the first time that a person’s beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.
Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel “genetic priority score” (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score. The findings were described in the January 3 online issue of Nature Genetics [DOI: 10.1038/s41588-023-01609-2]. Studies have shown that drugs have an increased likelihood of success in clinical trials when the genes they target have been demonstrated to have genetic support. The new tool integrates multiple lines of genetic evidence to prioritize these drug targets.
Researchers developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
The Matabele ants (Megaponera analis), which are widespread south of the Sahara, have a narrow diet: They only eat termites. Their hunting expeditions are dangerous because termite soldiers defend their conspecifics – and use their powerful mandibles to do so. It is therefore common for the ants to be injured while hunting.
In a report just published in the journal Nature Climate Change, researchers argue that tackling inequality is vital in moving the world towards Net-Zero – because inequality constrains who can feasibly adopt low-carbon behaviours.
Farmers in sub-Saharan Africa need to diversify away from growing maize and switch to crops that are resilient to climate change and supply enough key micronutrients for the population, according to a major research study.
Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.
Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers at the Max-Planck-Institute for Terrestrial Microbiology have developed a synthetic biochemical cycle that directly converts CO2 into the central building block Acetyl-CoA.
Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders. This discovery may pave the way for the development of improved medications targeting the same pathway. Their findings, detailed in the January 2 online issue of Nature Communications https://doi.org/10.1038/s41467-023-44601-4, show that a brain protein known as the TAAR1 receptor, a drug target known to regulate dopamine signaling in key reward pathways in the brain, differs significantly in humans compared to the preclinical rodent models on which drugs are typically tested. The study suggests considering species-specific differences in drug-receptor interactions and further investigation into ways asenapine affects the body, as steps toward potential therapeutic improvements.
Rutgers professor and other researchers perform a systematic review and meta-analysis to evaluate studies comparing perinatal outcomes among individuals with gestational diabetes mellitus
Amid the threat of dramatic sea level rise, coastal communities face unprecedented dangers, but a new study reveals that as flooding intensifies, disadvantaged populations will be the ones to experience some of the most severe burdens of climate change.
The physics of carbon-12 are extremely complex. This research computed the nuclear states of carbon-12 from first principles using supercomputers and nuclear lattice simulations.
Following years of research and the power of a technologically advanced instrument, UC San Diego scientists have detailed the complex nanoscale exoskeleton patterns of the roundworm, a model laboratory organism, revealing clues about how skin layers are bound together.
Conventional computer processors have pretty much maxed out their “clock speeds” — a measurement of how fast they can toggle on and off — due to limitations of electronic switching.
A research team from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has successfully harnessed artificial intelligence (AI) and deep-learning techniques to model atomic-level RNA 3D structures from primary RNA sequences.
The maintenance of a balanced lipid homeostasis is critical for our health.
As climate change drives more frequent and intense weather, finding new ways to adapt can be a matter of life or death.
The number of people affected by tropical cyclones has nearly doubled from 2002 to 2019, reaching nearly 800 million people in 2019, according to a new study.
A groundbreaking new technique invented by researchers at the USC Dornsife College of Letters, Arts and Science may revolutionize the field of synthetic biology. Known as CReATiNG (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), the method offers a simpler and more cost-effective approach to constructing synthetic chromosomes. It could significantly advance genetic engineering and enable a wide range of advances in medicine, biotechnology, biofuel production and even space exploration.
Technology developed at the University of Wisconsin–Madison to grow “rosettes” of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.It’s the latest discovery using RosetteArray technology, a screening tool that uses stem cells to generate embryonic forebrain or spinal cord tissue structures called neural rosettes.
A team of computational scientists at the Department of Energy’s Oak Ridge National Laboratory has generated and released datasets of unprecedented scale that provide the ultraviolet visible spectral properties of over 10 million organic molecules.
Heart rates are easier to monitor today than ever before. Thanks to smartwatches that can sense a pulse, all it takes is a quick flip of the wrist to check your heart.
The Beach Boys’ iconic hit single “Good Vibrations” takes on a whole new layer of meaning thanks to a recent discovery by Rice University scientists and collaborators, who have uncovered a way to destroy cancer cells by using the ability of some molecules to vibrate strongly when stimulated by light.
NEMO, a protein that is primarily associated with signaling processes in the immune system, prevents the deposition of protein aggregates that occur in Parkinson’s disease. For this purpose, it binds to certain protein chains that serve as markers for cellular waste removal, thus promoting the degradation of the harmful aggregates.
A microbial sensor that helps identify and fight bacterial infections also plays a key role in the embryonic development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.
Damage to the protein production capacity neutralizes the trypanosome parasite, which causes sleeping sickness. Joint research by Prof.
Where are the billions of trees people promised to plant? Forest restoration, especially in the tropics, is more complex than it seems and comes with major financial risks.
Artificial intelligence developed to model written language can be utilized to predict events in people's lives.
High-entropy alloys (HEAs) have potential uses in applications involving severe wear and tear, extreme temperatures, radiation, and high stress, but HEAs made using additive manufacturing often have poor ductility. Scientists have now used laser-based additive manufacturing to form stronger and more ductile HEAs.
Scientists at St. Jude Children’s Research Hospital identified genetic and epigenetic mechanisms driving predisposition to this childhood kidney cancer, impacting care and treatment.
Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.
Led by Aoxing Liu and senior authors Melinda Mills, Andrea Ganna and an international team, the study examined the link between 414 early-life diseases and lifetime childlessness in over 2.5 million individuals born in Finland and Sweden.
New research published in the January issue of Nature Cities examines, for the first time, the potential benefits of combining heat adaptation strategies with mitigation strategies to lessen heat exposure across major U.S. cities. It also identifies the regions in which these strategies could best benefit future populations.
Nature Communications today published research by an international team from Wits and ICFO- The Institute of Photonic Sciences, which demonstrates the teleportation-like transport of “patterns” of light – this is the first approach that can transport images across a network without physically sending the image, and a crucial step towards realising a quantum network for high-dimensional entangled states.
Researchers from the National University of Singapore (NUS) devise a simple and innovative way to directly identify and sort the immune cells involved in cell-mediated cytotoxicity.
Cardiovascular diseases are the leading cause of death in the world according to the Global Burden of Disease study, with 18.6 million annual deaths in 2019, of which around 7.9 are attributable to diet. This means that diet plays a major role in the development and progression of these diseases.
In a landmark study led by the University of Maryland School of Medicine, researchers discovered for the first time that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart.
Using laser scanning, researchers at the University of Helsinki have mapped out how the fragmentation of forests affects tree shape in the rainforests of Brazil. The results are surprising, as they shed light on the impact of human activity on the tropical environment and, consequently, on climate change in a new way.
Findings published in the journal Nature by physician-scientists at Beth Israel Deaconess Medical Center (BIDMC) and colleagues suggest that it may be possible to improve protection against COVID-19 by delivering the vaccine directly to the respiratory tract— the primary site of entry in SARS-CoV-2 infection.
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