A single dose of lithium chloride, a drug used to treat bipolar disease and aggression, blocks the sleep disturbances, memory loss, and learning problems tied to fetal alcohol syndrome, new experiments in mice show.
Making an AD mouse model that incorporates both Aβ and tau pathologies in a more AD-relevant context has been greatly sought after but difficult to accomplish. This study is a big step for AD research, which will allow testing of new therapies in a more realistic context.
Ludwig Cancer Research extends its warmest congratulations to Don Cleveland, who has been a Member of the Ludwig Institute for Cancer Research since 1995 and today was awarded the prestigious Breakthrough Prize.
Two past Presidents of the American Society for Cell Biology (ASCB), Don Cleveland and Peter Walter, are among the winners of the 2018 Breakthrough Prize in Life Sciences. Cleveland, a researcher at the University of California, San Diego, was 2013 ASCB President and Walter, a researcher at the University of California, San Francisco, was 2016 President.
Cannabis use in youth is linked to bipolar symptoms in young adults, finds new research by the University of Warwick.
A new study concludes excessive time on electronic devices is linked to a higher risk of depression and suicide among teenagers, especially girls.
Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant. In a paper published online in the journal Cancer Cell on November 30, University of California San Diego School of Medicine researchers identified a strategy that pinpoints a genetically distinct subpopulation of patients with glioblastoma that is particularly sensitive to drugs like cilengitide that target a cell adhesion receptor known as integrin αvβ3.
An antibody therapy against a key inflammatory molecule involved in migraines reduces the number of headaches that chronic migraine patients experience per month in a phase III trial.
Scientists at the Universities of Birmingham and Amsterdam hope to have found a new neurobiological marker to help recognise patients with post-traumatic stress disorder (PTSD).
A blood test to monitor a nerve protein in the blood of people with multiple sclerosis (MS) may help predict whether disease activity is flaring up, according to a study published in the November 29, 2017, online issue of Neurology® Neuroimmunology and Neuroinflammation, an official journal of the American Academy of Neurology.
A new study could bring a better scientific understanding of the unique stressors facing police officers. Expanding on a pilot study, the new project delves deeper into the effectiveness of an eight-week mindfulness-based program on police well-being and brings into the fold new collaborators in the law enforcement community.
People showing high levels of extraversion and conscientiousness may have protection against depression and anxiety, according to the results of a new study by a team of University at Buffalo psychologists.
A multi-disciplinary team of researchers with expertise in biology, anesthesiology, pharmacology, and medicinal chemistry at U of U Health received a $10 million grant from the Department of Defense to identify new, natural compounds to develop non-opioid drugs for pain management
White male gun owners who have lost, or fear losing, their economic footing tend to feel morally and emotionally attached to their guns, according to a Baylor University study. This segment of the population also is most likely to say that violence against the U.S. government is sometimes justified.
Media Pitch: People with a mental illness are twice as likely to have a substance use problem compared to the general population. At least 20% of people with a mental illness have a co-occurring substance use problem.
Women have smaller, more breakable nerve fibers in the brain compared to men that may make them more susceptible to concussions, suggests a new study from Penn Medicine neuroscientists published online today in the journal Experimental Neurology.
The final results of the DAWN study, published in The New England Journal of Medicine, show that select patients with stroke caused by a blood clot can be effectively treated with a procedure to remove the clot mechanically – and that this can be done up to 24 hours after the onset of symptoms.
Military sexual trauma (MST) is defined as sexual harassment and/or sexual trauma experienced during the course of military service. It includes uninvited or unwanted verbal or physical contact of a sexual nature, such as attention, verbal remarks, touching, sexual coercion, sexual assault, and rape. MST happens to both men and women, and can have mental and physical health consequences. However, little attention has been paid to the behavioral health consequences of MST, such as substance misuse. This study examined the prevalence of MST during deployment among male Reserve and National Guard soldiers, and the extent to which MST exposure during deployment was associated with frequent heavy drinking and alcohol problems post-deployment.
Understanding how brains actively erase memories may open new understanding of memory loss and aging, and open the possibility of new treatments for neurodegenerative disease.
Playing a video game that rewards participants for holding various “ninja” poses could help children and youth with autism spectrum disorder (ASD) improve their balance, according to a recent study in the Journal of Autism and Developmental Disorders led by researchers at the University of Wisconsin-Madison.
A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction—which can be caused by aging, pesticides and pollution—may contribute to Parkinson’s disease.
When family is gathered around the table, there are better -- and worse -- ways to deliver personal updates
A groundbreaking Loyola Medicine study suggests that a simple 15-minute electrocardiogram could help a physician determine whether a patient has major depression or bipolar disorder.
Diagnosing a concussion can sometimes be a guessing game, but clues taken from small molecules in saliva may be able to help diagnose and predict the duration of concussions in children, according to researchers at Penn State College of Medicine.
Aging research specialists have identified, for the first time, a form of mental exercise that can reduce the risk of dementia.
Nearly 15 percent of Kentucky children are currently diagnosed with ADHD, the highest rate in the nation. While medicine alone doesn't necessarily lead to improved academic performance in the long run, a new intervention developed by UK professors is aiming to do just that.
Using virtual reality therapy to improve arm and hand movement after a stroke is equally as effective as regular therapy, according to a study published in the November 15, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Denise Cai, PhD, Assistant Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai, has been selected as one of the Allen Institute for Brain Science’s 2017 Next Generation Leaders.
Study led by University of Maryland School of Social Work's Jodi Frey has resulted in more than 1,750 mental health screenings.
People sometimes joke that easy tasks are “not brain surgery.” But what happens when it actually is brain surgery? How old is too old to be a neurosurgeon? In a new Mayo Clinic Proceedings study, most neurosurgeons disagreed with an absolute age cutoff, but half favored additional testing for neurosurgeons 65 and older.
a new study concludes that two of the top medications available for outpatient, office-based treatment, once initiated, are equally safe and effective in curtailing opioid use, relapse, treatment drop-out and overdose.
University of Arkansas biomedical engineering doctoral student Asya Ozkizilcik has improved the nanowiring of drugs for an international team of researchers who are working on a new method for treating neurodegenerative diseases.
New research on the biological basis of psychiatric disorders has important implications for legal proceedings as well as mental health treatment, according to a special issue on "Psychiatry, Neuroscience, and the Law," presented in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.
McMaster University neuroscientists studying sports-related head injuries have found that it takes less than a full concussion to cause memory loss, possibly because even mild trauma can interrupt the production of new neurons in a region of the brain responsible for memory. Though such losses are temporary, the findings raise questions about the long-term effects of repeated injuries and the academic performance of student athletes.
NitroSynapsin is intended to restore an electrical signaling imbalance in the brain found in virtually all forms of autism spectrum disorder (ASD).
UT Southwestern’s O’Donnell Brain Institute will help in an international effort to map and characterize all the cells in the human body, an ambitious project aimed at gaining insight into how cellular changes can cause disease.
Ludwig Cancer Research has released the scope of its participation at this year’s Annual Meeting and Education Day of the Society for Neuro-Oncology in San Francisco, California, November 16-19.
A procedure to remove clots from blocked brain vessels – known as thrombectomy - may be beneficial for some stroke patients even if they come in to the emergency room beyond the 6-hour treatment window that current guidelines endorse, according to a groundbreaking study conducted by an international team of physicians and researchers.
Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.
A research team has identified the pathological mechanism for a certain type of autism and intellectual disability by creating a genetically modified mouse. They are hopeful it could eventually lead to a therapeutic fix.
Researchers at Georgetown University Medical Center have found distinct molecular signatures in two brain disorders long thought to be psychological in origin — chronic fatigue syndrome (CFS) and Gulf War Illness (GWI).
Obstructive sleep apnea (OSA) may put elderly people at greater risk of developing Alzheimer’s disease (AD), according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
The Department of Defense has awarded a multi-institutional team of scientists a series of grants totaling $4.37 million to investigate the potential role of airborne pollutants as triggers of Parkinson’s disease via the nose.
By teaching patients better strategies for coping with chronic pain, cognitive behavioral therapy (CBT) is a valuable treatment alternative for the millions of Americans taking opioids for noncancer pain, according to an article in the Journal of Psychiatric Practice. The journal is published by Wolters Kluwer.
CIHR-promoted researchers explore Post-traumatic stress disorder
Research by a team of Vanderbilt University Medical Center scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.
More mental health providers may want to take a closer look at including exercise in their patient's treatment plans, a new study suggests. Michigan State University and University of Michigan researchers asked 295 patients receiving treatment at a mental health clinic whether they wanted to be more physically active and if exercise helped improve their mood and anxiety.
Second Year Catherine Aranda helped organize Darden's inaugural Resilience Week, which featured panels discussions, speakers and a variety of event.
Genes linked to schizophrenia in psychiatric patients suffering from bipolar disorder are the reason why such patients don't respond to the "gold standard" treatment for bipolar – the drug lithium – according to international research led by the University of Adelaide.
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