Madeline Harris and Kristen Noles centered their careers on caring for patients at UAB Hospital; now they celebrate five years of breast cancer survivorship for Noles.
Researchers from UAB, Emory and Microsoft demonstrate that HIV has evolved to be pre-adapted to the immune response, worsening clinical outcomes in newly infected patients.
With a $2.5-million grant from the Gates Foundation's All Children Thriving initiative, UAB researchers are developing sensor-based devices that can detect signs of pre-term labor and predict which patients will encounter problems.
Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson’s.
Researchers have learned new information about how different people respond to aspirin, a globally prescribed drug in cardioprotection. The team identified more than 5,600 lipids in blood platelets and gained new insights into how these cells respond to aspirin.
UAB School of Nursing Professor David Vance, Ph.D., received a five-year, $2.86 million R01 grant to test ways of improving cognitive function in older adults with HIV.
Adam Gordon, O.D., discusses blue light, including the lack of clinical evidence in advertisements overstating dangers, as well as the effects of blue light on sleep and eye discomfort.
Researchers present data and a simple statistical network model that describe an unanticipated property of newly formed, immature neurons in the dentate gyrus.
The Medical Genomics Laboratory at UAB is expanding its technological array with a new panel of diagnostic tests for genetic diseases known as neurofibromatoses and rasopathies, using the technique called customized deep-coverage, next-generation sequencing or NGS.
Gift from United Therapeutics will establish UAB Xenotransplantation Program and bring additional resources to support the endeavor with a goal of genetically modified kidney transplants taking place by 2021.
Using satellite imaging, UAB archaeologist Sarah Parcak may have found evidence of the 2nd Norse settlement in North America at a site in Newfoundland.
In his new book, “What We Talk About When We Talk About Clone Club,” international expert on the ethics of human cloning, Gregory Pence, explores issues raised in the sci-fi show “Orphan Black” about human cloning, its ethics and impact on personal identity, genetic enhancement, and other mysterious science. Pence takes a lighthearted look at cloning in popular culture and explains when the show gets the science right and when it doesn’t.
Michelle Harris came to UAB on maximal life support, unsure if she would live after a rare multisystem autoimmune disease attacked her lungs. Now, she goes home with her eyes on upcoming prom, graduation.
Researchers made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using a laser-scanning method called MALDI tissue imaging to localize the changes.
Developmentally appropriate activities conducted by parents with their child during the first three years after birth reduce childhood cognitive delays in low-resource families.
Kejin Hu, Ph.D., has found a robust reprogramming factor that increases the efficiency of creating human induced pluripotent stem cells (HiPSCs) from skin fibroblasts more than 20-fold, speeds the reprogramming time by several days and enhances the quality of reprogramming.
The protective effect of heme oxygenase-1 and its mechanism are described. Overexpression of this enzyme could protect the heart from life-threatening damage after cancer chemotherapy, and it also may be a way to increase the therapeutic window of such drugs.
Study shows that, although ZEBRA, a system intended to enable prompt and user-friendly deauthentication, works very well with honest people, opportunistic attackers can fool the system.
A small regulatory RNA called microRNA-155 appears to play a key role in the brain inflammation that helps foster Parkinson’s disease. This finding, using a mouse model, implicates microRNA-155 as both a potential therapeutic target and biomarker for this progressive neurodegenerative disorder.
The pathway leading to increased expression of TGF-β1 — which provokes the destructive lung remodeling of pulmonary fibrosis — involves Akt1 kinase-induction of reactive oxygen species and mitophagy, and alveolar macrophages are the primary source of TGF-β1 in the lung.