Are Cyclists Pedaling Towards Osteoporosis?

Newswise — While maintaining a steady exercise regimen is one of the best things people can do for their general good health, recent studies suggest an alarming correlation between bicycling and the onset of osteopenia (lower-than-normal bone density) or osteoporosis (very low bone mineral density), even among those who are young and fit.

A low-impact sport that puts little mechanical load on the bones and joints, bicycling is a wonderful cardiovascular exercise that people can enjoy into their later years. When it comes to the risk of thinning bones, however, it's the weight-bearing nature of exercise that signals bones to create more mass. Without such stress, bones do not get stronger, and become more prone to injury.

A recent study that appeared in Medicine & Science in Sports & Exercise found that competitive male road cyclists showed significantly lower bone mineral density in their spines than a control group of men who were moderately physically active. Although the cyclists had a greater calcium intake, they were still more likely to have osteopenia and osteoporosis than those in the control group. A similar study in Bone illustrated that male road cyclists had lower bone mineral density than male mountain bikers after adjusting for body weight and age. The distinction could be found in that mountain biking, with its variable terrain, provides more impact for bone growth than road cycling or racing. Swimmers may also be at risk, because that sport requires similarly little mechanical loading, leaving the lower spine particularly vulnerable.

Another challenge facing cyclists and swimmers in relation to bone density is caloric intake. Cycling and swimming are notorious for burning up calories (witness, Michael Phelps's notorious 12,000 calorie diet), however, hard-core cyclists may not be eating enough to offset what they burn when they exercise, depriving their bodies of bone-strengthening nutrients such as calcium and vitamin D. These caloric shortfalls could also trigger physiological problems such as lower levels of estrogen in women and testosterone in men, both hormones that have protective effects on bones and slow the rate of bone breakdown.

"Unfortunately, many people consider osteoporosis a disease that primarily concerns women and the elderly," says Dr. Warren P. Levy, President, and CEO of Unigene Laboratories. "Of course, exercise is good for people, but in order to maintain healthy bones, avid cyclists and swimmers should be mindful of incorporating cross-training weight-bearing exercise into their routines. People do not achieve peak bone mass until their late twenties, so if cyclists or swimmers are in their early or mid twenties, and they're not doing any exercise that's going to load their spine and help them achieve peak bone mass, they may be putting themselves at risk for a fracture."

Boning Up On Treatments Early screening by physicians can help identify patients at risk of bone loss. The most commonly prescribed treatment for osteoporosis today is a class of drugs known as bisphosphonates. Bisphosphonates are the active ingredient in widely prescribed osteoporosis treatments such as Fosamax, Actonel and Boniva. These medicines work by effectively preventing further bone loss by osteoclast cells, preserving bone density. In some instances however, users of bisphosphonates have experienced side effects including osteonecrosis of the jaw (a degenerative disease that may result in infections that will not heal, lost teeth or jaw collapse), severe muscle or joint pain, sudden low energy leg fractures, irregular heart rhythms, or esophageal cancer.

"We still have a lot to learn about bone health and that everyone, even younger males, need to be aware of bone health," adds Levy.

Unigene Laboratories seeks to provide osteoporosis sufferers, male and female alike, with a natural, effective treatment. The active ingredient in Unigene's peptide-based nasally delivered osteoporosis treatment is salmon calcitonin, which in more than 35 years of human use poses virtually no significant side effects. It is available today in a prescription drug called Fortical.

For more information log on to www.unigene.com or http://www.irgnews.com/coi/ugne