Be one of the first to read the October 2020 issue of the journal Diseases of the Colon and Rectum! Here are the editor's top picks

Title: High-Resolution Anoscopy Surveillance After Anal Squamous Cell Carcinoma: High-Grade Squamous Intraepithelial Lesion Detection and Treatment May Influence Local Recurrence

Video Creator: Carmelina Cappello, M.D. • Tamzin Cuming, F.R.C.S. • Julie Bowring, MBChB. •  Adam N. Rosenthal, Ph.D. • Noreen Chindawi, B.Sc. • Mayura Nathan, MBBS, F.R.C.P.

Description:   High-grade squamous intraepithelial lesions after anal squamous cell carcinoma are more common after excision only than after chemoradiation. Local recurrence is low in this high-resolution anoscopy surveillance group in which high-grade squamous intraepithelial disease was ablated. Excision of small perianal cancers appears safe; however, a subset of patients is at excess risk.

Title: Segmental Colonic Resection Is a Safe and Effective Treatment Option for Colon Cancer of the Splenic Flexure: A Nationwide Retrospective Study of the Italian Society of Surgical Oncology–Colorectal Cancer Network Collaborative Group

Video Creator: Maurizio Degiuli, M.D. • Rossella Reddavid, M.D. • Fulvio Ricceri, Ph.D.   • Francesca Di Candido, M.D. • Monica Ortenzi, M.D. • Ugo Elmore, M.D.   • Claudio Belluco, M.D., Ph.D. • Riccardo Rosati, M.D. • Marco Guerrieri, M.D.   • Antonino Spinelli, M.D., Ph.D. •   and Members of the Italian Society of Surgical Oncology Colorectal Cancer Network (SICO-CCN) Collaborative Group 

Description:  Segmental resection is a safe and effective treatment option for cancer of the splenic flexure.

Title: Clinical Decision Support for High-Risk Stage II Colon Cancer: A Real-World Study of Treatment Concordance and Survival

Video Creator: Peng-ju Chen, M.D. • Tian-le Li, M.D. • Ting-ting Sun, M.M.S.  •  Van C. Willis, Ph.D. • M. Christopher Roebuck, Ph.D.  •  Dena M. Bravata, M.D., M.S. • Xin-zhi Liu, M.D.  •  Yull Edwin Arriaga, M.D. • Irene Dankwa-Mullan, M.D., M.P.H.  •  Ai-wen Wu, M.D., Ph.D.

Description:  Watson for Oncology produced therapeutic options highly concordant with human decisions at a top-tier cancer center in China. Treatment patterns suggest that Watson for Oncology may be able to guide clinicians to minimize overtreatment of patients with high-risk stage II colon cancer with chemotherapy. Survival analyses suggest the need for further investigation to specifically assess the association between surveillance, single-agent and multiagent chemotherapy, and survival outcomes in this population.

Title: Prophylactic Gynecologic Surgery at Time of Colectomy Benefits Women with Lynch Syndrome and Colon Cancer: A Markov Cost-Effectiveness Analysis

Video Creator: Asya Ofshteyn, M.D., M.P.H. • Boxiang Jiang, M.D. • Katherine Bingmer, M.D.  •  John M. Nakayama, M.D. • Carlos Gallego, M.D. • Matthew Giglia, M.D. • Sharon L. Stein, M.D. • Emily Steinhagen, M.D.

Description:  Total abdominal colectomy with prophylactic hysterectomy at 30 years of age was the most cost-effective surgical choice in women with Lynch syndrome and colon cancer. The addition of bilateral salpingo-oophorectomy offered the highest event-free survival and lowest mortality. However, the additional morbidity of premature menopause of prophylactic salpingo-oophorectomy for younger women outweighed the benefit of ovarian cancer prevention.

Title: Is Same-Day and Next-Day Discharge After Laparoscopic Colectomy Reasonable in Select Patients?

Video Creator: Nicholas P. McKenna, M.D. • Katherine A. Bews, B.A. • Omair A. Shariq, M.B.B.S.   • Elizabeth B. Habermann, Ph.D. • Kevin T. Behm, M.D. • Scott R. Kelley, M.D.   •David W. Larson, M.D.

Description:  Discharge on the same day or next day after surgery was not associated with increased risk compared with discharge on postoperative day 3 to 5, and it did not result in a high rate of early readmissions. Increased use of expedited discharge pathways would reduce hospital costs and resource use.