A new class of oral drugs can inhibit a wide range of SARS-CoV-2 variants, researchers report, potentially identifying new antiviral agents providing broad activity against the constantly emerging new strains of the COVID-19 virus
The link between symptoms of COVID-19 and physical inactivity is increasingly evident. An article recently published in the journal Scientific Reports by researchers at the University of São Paulo (USP) in Brazil describes a study in which COVID-19 survivors with at least one persistent symptom of the disease were 57% more likely to be sedentary, and the presence of five or more post-acute sequelae of infection by SARS-CoV-2 increased the odds of physical inactivity by 138%.
A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.
The same genetics that helped some of our ancestors fight the plague is still likely to be at work in our bodies today, potentially providing some of the population with extra protection against respiratory diseases such as COVID-19. However, there is a trade-off, where this same variation is also linked to increased autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
The research team consists of six investigators who will lead three separate project grants and three separate cores, in the hopes of finding new avenues for research and treatments to help patients who suffer from conditions like chronic obstructive pulmonary disorder, pulmonary fibrosis and acute respiratory distress disorder, a common and serious complication of COVID-19.
A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.
Bioengineers from Columbia University are developing a pipeline to systematically evaluate how bacterial treatments might synergize with existing anti-cancer therapies in preclinical models.
Lung cancer patients with moderate to severe depression are 2 to 3 times more likely to have inflammation levels that predict poor survival rates, a new study found. The results may help explain why a substantial portion of lung cancer patients fail to respond to new immunotherapy and targeted treatments that have led to significantly longer survival for many people with the disease.
Patients with serious pneumococcal infections, including pneumonia and sepsis, are at a substantially increased risk of heart attack after the onset of infection.
New insights into the importance of early-life factors on lung health have been unveiled in the most comprehensive study of its kind, led by the Universities of Essex and Bristol.
Despite COPD’s pervasiveness, it is generally assumed that the main instigator in its development is tobacco smoking. The 2023 Global Initiative for Chronic Obstructive Lung Disease or GOLD report is proposing a new definition of COPD, one that acknowledges the key pathogenic role of tobacco smoking but accounts for other factors that also contribute to COPD.
Schools are among the most notable settings people associate with picking up viral infections such as the common cold, various types of the flu or other respiratory viruses.
The Red Tide Respiratory Forecast — www.RedTideForecast.com — is a beach-level risk forecast activated during red tide conditions that tells beachgoers what red tide impacts are expected to be at individual beaches at different times of the day. The Forecast is also available in Spanish at www.PronosticoMareaRoja.com.
Hackensack Meridian Jersey Shore University Medical Center recently celebrated the opening of a new, specialized Pulmonary Hypertension Center.
Vaping cannabidiol (CBD), a compound found in marijuana, leads to more severe lung damage than vaping nicotine, according to a study out of Roswell Park Comprehensive Cancer Center. Until now, research on the health effects of vaping, or using e-cigarettes, has focused almost exclusively on vaping nicotine as opposed to CBD. Previous research has documented the effects of smoking cannabis, but the effects of vaping cannabinoids such as CBD were not previously known.
UC San Francisco researchers have uncovered a surprising role for fibroblasts in the lungs in activating T cell inflammation that drives lung destruction in COPD exacerbation triggered by viral infection. They also identified a T cell subset that can be targeted to treat COPD exacerbations.
A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protects cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease. The study was published in Nature Communications.
The Pulmonary Fibrosis Foundation (PFF) recognizes Rare Disease Day on February 28 and emphasizes the importance of empowering those living with or impacted by rare conditions, like pulmonary fibrosis (PF), to promote advocacy, education, and awareness.
Although the public had been alerted that this winter could be a potentially bad flu season, barely half of Americans said in January that they had received a flu shot, a vaccination level unchanged in a representative national panel from the comparable period last year.
The PFF celebrates and honors Black History Month this February. The PFF advocates for increasing diversity of patient representation through the PFF Community Registry to enhance research and improve treatment options for those in the African-American and other communities.
Internationally renowned expert will focus on growing St. Jude into a global leader in infectious diseases research.
Researchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed on drug-resistant cancer cells in EGFR-mutant non-small cell lung cancer (NSCLC), highlighting a novel therapeutic target that could be used to eliminate resistant cells remaining after treatment with commonly used EGFR tyrosine kinase inhibitors (TKIs). The study published today in Cancer Cell.
A newly published animal study found that chronic alcohol consumption may create conditions in the body that can facilitate infection by SARS-CoV2, the virus that causes COVID-19 disease. The study, published in Alcohol: Clinical and Experimental Research, found that chronic alcohol use increased the levels of an enzyme that helps the virus enter the cells and, therefore, may increase the risk for COVID-19.
Smoking tobacco and vaping electronic cigarettes may increase healthy young people’s risk for developing severe COVID illness.
University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.
More U.S. high school seniors reported vaping cannabis in states where it is legal only for medical purposes than states where all adult use is permitted – a study finding that surprised the researchers.
Researchers have developed an inhalable powder that could protect lungs and airways from viral invasion by reinforcing the body’s own mucosal layer.
A study of adolescents aged 11-16 in London has found long-term exposure to PM2.5 is associated with higher blood pressure, with stronger associations seen in girls.
Utilizing artificial intelligence (AI) along with traditional pathology offers promise for swiftly developing treatment plans for patients with non-small cell lung cancers, a team led by UT Southwestern Medical Center researchers discovered.
Taking vitamin D supplements does not reduce the risk of asthma attacks in children or adults, according to an updated Cochrane review.
Risk model-based lung cancer screening strategies, which select individuals based on personal risk, are more cost effective than current recommendations based solely on age and smoking history, according to a study led by the Cancer Intervention and Surveillance Modeling Network (CISNET) Lung Working Group, which includes researchers from The University of Texas MD Anderson Cancer Center.
The severity of a lung disease associated with e-cigarettes in teens decreased during the COVID-19 pandemic, but hospitalizations from the disease continued to mount, according to a study of more than three dozen patients by UT Southwestern researchers published in Pediatric Pulmonology.
Replacing traditional biomass-burning cookstoves across sub-Saharan Africa could save more than 463,000 lives and US $66 billion in health costs annually, according to a new analysis of the most socially optimal cooking technologies in Africa.
Each month, we’d like to highlight some current work at Huntsman Cancer Institute. See how a potential new immunotherapy for breast cancer is being developed, learn about research being done to prevent cancer risks in young adults, gain an understanding of how a specific DNA mutation can change lung cancer tumors, check out how nurses are creating a new way to monitor a serious type of pneumonia, and read how researchers have linked biomarkers to distress in colorectal cancer patients.
Immunotherapy — drug treatment that stimulates the immune system to attack tumors — works well against some types of cancer, but it has shown mixed success against lung cancer.
Researchers at Moffitt Cancer Center are investigating new treatment approaches for this patient population. In a new article published in the International Journal of Radiation Oncology, Biology and Physics, our team of physicians, led by Daniel Oliver, M.D., and Stephen Rosenberg, M.D., shows that stereotactic body radiotherapy, or SBRT, is an effective treatment for patients with early stage lung neuroendocrine tumors.
The tuberculosis vaccine (or BCG vaccine) does not protect elderly with co-morbidities against disease symptoms caused by a coronavirus infection.
Todd Florin, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago recently was awarded a $5.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) for a multicenter study to derive and broadly validate the first emergency department (ED)-based pediatric community-acquired pneumonia severity (PedCAPS) score. This objective score will help avoid many unnecessary hospitalizations in children at low risk of severe outcomes, while targeting more focused therapies towards the lower proportion of children at highest risk for severe disease.
People with weakened immune systems remain more likely to die if hospitalised with COVID-19 than patients with normal immune systems, a new UK study has confirmed.
Over four percent of deaths in cities during the summer months are due to urban heat islands, and one third of these deaths could be prevented by reaching a tree cover of 30%, according to a modelling study published in The Lancet and led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa” Foundation.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Below are some of the latest articles that have been added to the Surgery and the Transplantation channels on Newswise, a free source for journalists.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
The largest trial in limited-stage small cell lung cancer ever suggests similar outcomes and long-term survival in patients treated with twice-a-day versus once-a-day radiotherapy.
Johns Hopkins Medicine investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains
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