Feature Channels: All Journal News

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While the health effects of breastfeeding are well-recognized and apply to both mothers and children, some mothers may not be able to produce a milk supply to meet the needs of their child. When infants require hospitalization in the immediate newborn period doing to being born preterm or having other health complications, human milk is a vital life-saving medical intervention.

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A team led by Columbia University Biomedical Engineering Professor Gordana Vunjak-Novakovic has designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts.

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A drug that failed to effectively strike larger targets in lung cancer hits a bulls-eye on the smaller target presented by a previously untreatable form of the disease, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

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Using advanced imaging technology, researchers observe new patterns of molecular organization as connections between neurons strengthen during learning.

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Study shows potential link between Parkinson’s disease and inflammatory bowel disease, suggests anti-TNFα therapy may reduce the risk of developing Parkinson’s disease

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An international team, led by Berkeley Lab scientists, has demonstrated a breakthrough in the design and function of nanoparticles that could make solar panels more efficient by converting light usually missed by solar cells into usable energy.

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Study looked at 46 women across two different age ranges, 60-74 and 75-90, to learn how physical activity affects frailty differently in the two groups

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Rutgers New Jersey Medical School and collaborators from Shanghai University in China examined more than 6,000 compounds and identified a drug that relaxes the muscles and opens the airways, allowing those with asthma to breathe. Find out why this new therapy might give people a better option and new hope.

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Bringing black parents into school settings can work toward shifting and closing the cultural disconnects between black families and predominantly white school personnel, according to new research from Binghamton University, State University of New York.

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WASHINGTON -- If you’ve had a bad day at work thanks to rude colleagues, doing something fun and relaxing after you punch out could net you a better night’s sleep.

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Investigators at Rutgers Cancer Institute have discovered that some mutations detected in comprehensive, clinical genome sequencing of patients with solid tumors do not originate from cancer cells, but arise from mutated hematopoietic cells that infiltrate the tumor microenvironment. The findings, they say, have direct implications for cancer patients, specifically in accurately interpreting their molecular testing results and ensuring that treatment is focused on somatic tumor-specific mutations.

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Nature has inspired a coating for synthetic leather that repels oil and water—and keeps the material from getting sticky in the heat.

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To explore causes of hospital readmissions, researchers created a tool to identify and quantify a patient’s feelings of uncertainty during their initial emergency department visit.

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It might seem surprising that a colony of ants would tolerate the type of guests that gobble both their grub and their babies. But new research shows there’s likely a useful tradeoff to calmly accepting these parasite ants into the fold: They have weaponry that’s effective against their host ants and a more menacing intruder ant.

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An international team of scientists including the University of Adelaide has discovered a new complex carbohydrate in moss that could possibly be exploited for health or other uses.

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A new study of guenon monkeys in Gombe National Park is the first to provide genetic evidence of ongoing mating between two distinct species. These monkeys have successfully been producing hybrid offspring for hundreds maybe even thousands of years. Prior studies have suggested that their different physical characteristics keeps them from interbreeding. So, if their faces don’t match, they shouldn’t be mating, right? Wrong, according to this latest evidence.

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A treatment gap remains for many conditions involving damage to the liver, the body’s main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

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One of the most frustrating and debilitating complications of diabetes is the development of wounds on the foot or lower leg. Once they form, they can persist for months, leading to painful and dangerous infections.

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Article describes effect of ion and electron heating on multiscale turbulence in fusion plasmas.

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There’s increasing physiological evidence connecting breathing patterns with the brain regions that control mood and emotion. Now researchers have added neurons associated with the olfactory system to the connection between behavior and breathing. Connecting patterns in these interactions may help explain why practices such as meditation and yoga that rely on rhythmic breathing can help people overcome anxiety-based illnesses.

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A $2 million investment from a Denver angel investor group is the latest step forward for the biomedical startup CNine Biosolutions. Two entrepreneurs are using technology they developed at UAB to create a rapid and simple test to distinguish bacterial meningitis from viral meningitis.

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Researchers from the University of California, Irvine, Georgetown University and the University of Rochester have found that specific small molecules in blood plasma may be useful in determining whether someone has sustained a mild traumatic brain injury (mTBI), commonly known as a concussion.

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A Saint Louis University professor has developed a method for teaching a new language through gaming.

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In the largest study of its kind, researchers at the University of Minnesota and University of Toronto have revealed a complex network of genes that work together. Understanding those genetic connections can help develop new life-saving treatments to combat diseases such as cancer, heart disease, and diabetes.

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A recent article in Muscle & Nerve – “The Usefulness of Electrodiagnostic Studies in the Diagnosis and Management of Neuromuscular Disorders” proves the value and importance of electrodiagnostic testing to patient care.

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Need stronger timber, better biofuel or new sources of green chemicals? A systems biology model built on decades of NC State research will accelerate progress on engineering trees for specific needs.

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A Mayo Clinic study of children who received one or more exposures to anesthesia before the age of 3 has provided valuable information about the potential neurological and behavioral impact of general anesthesia on very young children, according to the International Anesthesia Research Society and the Society for Pediatric Anesthesia.

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People with diabetes can expect 15 per cent cost saving and three-fold reduction in hospital admissions with pharmacist-managed care

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You can wear an exoskeleton, but it won’t turn you into a superhero. In the journal Applied Ergonomics, researchers report that that a commercially available exoskeleton relieved stress on the arms just as it was supposed to—but it increased stress on the back by more than 50 percent.

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Often people think performing in front of others will make them mess up, but a new study led by a Johns Hopkins University neuroscientist found the opposite: being watched can make people do better.

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A multidisciplinary team of scientists share recent advancements in innovative in-vitro cancer biology methods for screening drug-like molecules in cancer tissue relevant models in a new report published online ahead-of-print at SLAS Discovery. Entitled "Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening," the report can be accessed for free.

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The famous Oxford Dodo died after being shot, according to breakthrough research by Oxford University Museum of Natural History and WMG at the University of Warwick.

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• Sixty-four percent of US patients undergoing hemodialysis in 2011 received opioids for pain, which is one of the most common reported symptoms in this patient population. • Opioid use was associated with higher risks of altered mental status, fall, and fracture in a dose-dependent manner, and these risks were present even when patients were not prescribed high opioid doses.

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An epidemiological study conducted by researchers at University of California San Diego School of Medicine and Seoul National University suggests that persons deficient in vitamin D may be at much greater risk of developing diabetes. The findings are reported April 19 in PLOS One.

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Cancer immune cell therapy has made headlines with astounding successes like saving former U.S. President Jimmy Carter from brain cancer. But immunotherapy has also had many tragic flops. Georgia Tech researchers working to optimize the innovative treatment have implanted a genetic switch that activates T-cells when they are inside of tumors. Remote-control light waves resembling those used in a TV remote combine with gold nanorods to flip the switch.

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Scientists have re-created brain neurons of obese patients using "disease in a dish" technology, offering a new method to study the brain's role in obesity and possibly help tailor treatments to specific individuals.

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A host of nuclear RNA-binding proteins, when misplaced outside the nucleus, form the harmful clumps seen in several brain disorders, including FTD and ALS. Clumps that form from these disease proteins are composed of sticky fibrils that damage nerve cells.

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In this issue, find research on Race and opioids, heroin overdose death undercount, folate during pregnancy, age of sexual initiation and health outcomes

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In a groundbreaking paper published today in the journal Cell, investigators at the Cancer Research Institute Beth Israel Deaconess Medical Center (BIDMC) have found dozens of important new genes, both coding and non-coding that impact sensitivity to chemotherapy. In doing so, the scientists developed a novel technique that marries CRISPR technology with big data mining to identify and assign function to non-coding RNAs

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After testing more than 200,000 chemical compounds, UT Southwestern’s Simmons Cancer Center researchers have identified 170 chemicals that are potential candidates for development into drug therapies for lung cancer.

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Researchers in the Department of Astrophysical and Planetary Science have completed an unprecedented "dissection" of twin galaxies in the final stages of merging.

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In recent years, researchers have firmly established that gene mutations appearing for the first time, called de novo mutations, contribute to approximately one-third of cases of autism spectrum disorder. In a new study, a team led by scientists at University of California San Diego School of Medicine have identified a culprit that may explain some of the remaining risk: rare inherited variants in regions of non-coding DNA. The findings are published April 20 in Science.

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An international team of scientists have developed a new cell imaging technology combining lattice light sheet microscopy (LLSM) and adaptive optics (AO) to create high-resolution “movies” of cells in their 3D environment that also captures subcellular processes

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Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet and legs. The researchers used the compound to treat the nerves of mice harboring the genetic defects that cause the disease.

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El estudio descubrió que cuando los pacientes se someten al trasplante doble, el hígado tiene un efecto protector sobre el riñón.

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Both civilians and military veterans with post-traumatic stress disorder (PTSD) reap long-term benefits from psychotherapies used for short-term treatment, according to a new study from Case Western Reserve University.

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Scientists at The Scripps Research Institute have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate.

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Engineers at the University of Washington have developed a new HD video streaming method that doesn’t need to be plugged in. Their prototype skips the power-hungry components and has something else, like a smartphone, process the video instead.

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Triple-negative breast cancer (TNBC) is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment. A team at The University of Texas MD Anderson led a study which may explain how resistance evolves over time, and potentially which patients could benefit from chemotherapy.

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Scientists have for the first time found direct causal links between the neurotransmitter dopamine and avoidance – behavior related to pain and fear. Researchers have long known that dopamine plays a key role in driving behavior related to pleasurable goals, such as food, sex and social interaction. In general, increasing dopamine boosts the drive toward these stimuli. But dopamine’s role in allowing organisms to avoid negative events has remained mysterious.