In a recent study, researchers from Montreal assess how six previously identified plant extracts can delay aging by affecting different signalling pathways that set the pace of growing old.
New York University biologist Elodie Ghedin will study the host response to Zika virus infections under a $1 million grant from the National Institute of Allergy and Infectious Diseases.
Johns Hopkins researchers report evidence from mouse studies that a “repurposed” drug that would be expected to improve the immune system response of tuberculosis patients may be increasing resistance to the antibiotic drugs these patients must also take.
Researchers from Massachusetts Eye and Ear/Harvard Medical School have found that patients who were prescribed corticosteroids as part of treatment for Lyme disease-associated facial paralysis had worse long-term outcomes of regaining facial function than those who were prescribed antibiotic therapy alone. Based on these findings, which were published online today in Laryngoscope, the researchers urge caution in prescribing corticosteroids to patients with acute Lyme disease-associated facial paralysis.
Mayo Clinic Monthly News Tips, August 2016
Zika virus is able to infect the eye, according to researchers at Washington University School of Medicine in St. Louis. The study, in mice, helps explain why some people with Zika virus develop eye disease, and suggests that contact with infected eyes may play a role in spreading the disease.
Researchers at Washington University School of Medicine in St. Louis published a study that shows that genetic material from the Zika virus has been found in tears. The study, fast-tracked for publication in Cell Reports, was conducted in mice, thereby creating an animal model for studying transmission and treatment of this alarming virus. The study, published September 6, 2016, also confirms that the Zika virus can lead to cell death in the eyes. Research to Prevent Blindness, located in New York, provided funding for this study.
Dr. Jonathan Karn has been awarded the 2016 Drexel Prize in Translational Medicine by the Institute for Molecular Medicine and Infectious Disease at Drexel University College of Medicine in Philadelphia.
Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington’s disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse the mutated gene effects responsible for HD.
Heavy drinking frequently causes liver inflammation and injury, and fatty acids (FAs) involved in pro- and anti-inflammatory responses could play a critical role in these processes. This study evaluated heavy drinking and changes in levels of omega-6 (ω-6, pro-inflammatory) and omega-3 (ω-3, anti-inflammatory) FAs in alcohol dependent (AD) patients who showed no clinical signs of liver injury.
Today’s news is flooded with reports on Zika; none of them good…until now. Texas A&M AgriLife Research has fielded a Zika team led by two scientists who joined the department of entomology at Texas A&M University.
Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.
The only approved vaccine for dengue may actually increase the incidence of dengue infections requiring hospitalization rather than preventing the disease if health officials aren’t careful about where they vaccinate, new public health research published Sept. 2 in Science suggests.
A new influenza virus that affects cattle has an official name. influenza D. The executive committee of the International Committee of Taxonomy of Virus approved a new genus, Orthomyxovirdae, with a single species, Influenza D virus, because of its distinctness from other influenza types—A, B and C.
Whitehead Institute researchers have conducted the first genome-wide screen in Apicomplexa, a phylum of single-celled parasites that cause diseases such as malaria and toxoplasmosis. The screen sheds light into the vast, unstudied reaches of parasite genomes, uncovering for instance a protein common to all apicomplexans.
Mayo Clinic will offer the Zika virus antibody test developed by the Centers for Disease Control and Prevention (CDC).This test has received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) and has been licensed to select national reference laboratories, including Mayo Medical Laboratories (MML).
Heart abnormalities linked to immersion pulmonary edema were present in a greater-than-expected proportion of triathletes who died during the competition’s swim portion, according to a study led by researchers at Duke Health.
Every minute, someone comes into a hospital emergency department in the United States with sepsis, a life-threatening over-response to infection that damages tissues and organs. The CDC recently declared sepsis a medical emergency.
A team of researchers from the University of Notre Dame’s Eck Institute for Global Health has received a grant from the USAID to develop an insecticide to destroy Aedes aegypti larvae before the mosquitoes are able to hatch and transmit Zika.
In a study of children with brain shunts at Children’s of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current “gold standard” test for detecting bacterial infections in the shunts.
Researchers are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness.
A new quality improvement initiative that aims to create effective solutions in optimizing adult vaccination rates was announced today. The program, the Adult Immunization Project, is a collaboration among the Duke Clinical Research Institute (DCRI), Duke Primary Care, Pfizer, and Premier. Researchers will jointly work to develop evidence-based interventions to support indicated adult vaccination practices among providers in the Duke Health system
Chronic fatigue syndrome (CFS) is a mysterious and maddening condition, with no cure or known cause. But researchers at the University of California San Diego School of Medicine, using a variety of techniques to identify and assess targeted metabolites in blood plasma, have identified a characteristic chemical signature for the debilitating ailment and an unexpected underlying biology: It is similar to the state of dauer, and other hypometabolic syndromes like caloric restriction, diapause and hibernation.
As Zika continues to dominate news headlines and political discussions, the O’Neill Institute for National and Global Health Law Colloquium hosts “Zika Virus: Our Common Future,” a panel discussion led by Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases.
Scientists report that a specialized drug screen test using lab-grown human cells has revealed two classes of compounds already in the pharmaceutical arsenal that may work against mosquito-borne Zika virus infections.
A team of researchers from Florida State University, Johns Hopkins University and the National Institutes of Health have found existing drug compounds that can both stop Zika from replicating in the body and from damaging the crucial fetal brain cells that lead to birth defects in newborns. One of the drugs is already on the market as a treatment for tapeworm.
People with blood type O get sicker from cholera than people of other blood types. Researchers from Washington University School of Medicine in St. Louis have found that cholera toxin activates a key molecule more strongly in people with blood type O than type A, possibly worsening symptoms.
Tuberculosis (TB) is the leading cause of death worldwide among people infected with HIV. But as yet, no test can reliably show when latent (inactive) TB infections in people with HIV starts progressing to active—and potentially fatal—TB disease. Now, a researcher at Albert Einstein College of Medicine has received a five-year, $3.7 million National Institutes of Health grant to identify biomarkers that signal an increase in activity by Mycobacterium tuberculosis (Mtb), the bacterium that causes TB, in people with HIV.
American Autoimmune Related Diseases Association (AARDA) announced today its August Autoimmune Heroes – the 46 Board members and advisors who have loyally and generously donated their time and talents to helping AARDA and its mission evolve and grow these last 25 years.
New Orleans, LA - Dr. John England, Professor and Chair of Neurology at LSU Health New Orleans School of Medicine, and colleagues in Honduras and Venezuela have reported a new neurological complication of infection with the Zika virus. They described the first confirmed case of Zika-associated sensory polyneuropathy in a paper published online by the Journal of the Neurological Sciences, available at http://www.jns-journal.com/article/S0022-510X(16)30535-4/abstract.
The USDA's National Institute of Food and Agriculture supports NoroCORE, a multidisciplinary research collaborative of 30 researchers from 25 universities who are joining forces to understand and control food borne virus risks.
Washington, DC - August 26, 2016 - Several species of bacteria found in smokeless tobacco products have been associated with opportunistic infections, according to a paper published August 26 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
The U.S. Food and Drug Administration (FDA) on Friday issued an advisory that all U.S. blood banks screen donated blood for Zika virus.
University of Colorado Cancer Center researcher shows that women who contract malaria while pregnant may have children with an increased risk of Burkitt's lymphoma.
Case Western Reserve University School of Medicine has received a five-year renewal program project grant totaling $9.7 million from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institute of Health, with the goal of better understanding the origins of Crohn's disease and eventually developing a cure.
In “Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome,” published in the most recent PLOS Neglected Tropical Diseases, the authors analyze Zika fetal neuropathogenesis from a comparative pathology perspective.
BOSTON – In a special report released August 23 in the journal Radiology, a team of researchers including Deborah Levine, MD, Director of Obstetric & Gynecologic ultrasound at Beth Israel Deaconess Medical Center (BIDMC) and professor of radiology at Harvard Medical School (HMS), documented the brain abnormalities associated with congenital Zika in 45 confirmed and presumed cases from northeastern Brazil.
New research published in the UEG Journal1 has found that Crohn's disease sufferers experience slower response times than matched individuals that do not have the disease.
Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders.
Nearly 400 non travel-related Zika infections will occur in Florida before the end of the summer, according to new projections by biostatisticians at the University of Florida and other institutions.
About 40 per cent of the population have a genetic disposition to celiac disease, but only about one per cent develop the autoimmune condition when exposed to gluten, and this could be promoted by the type of bacteria present in the gut. Researchers at McMaster University have found that gluten, a common protein in the Western diet which is not well digested by the gut enzymes, could be metabolized by bacteria.
As the number of patients with Zika virus grows worldwide, Johns Hopkins Medicine announces the opening of the new Johns Hopkins Wilmer Zika Center dedicated primarily to caring for patients with the mosquito-borne and sexually transmitted virus. The center is composed of providers and staff from departments and divisions at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health, including epidemiology, infectious diseases, maternal-fetal medicine, ophthalmology, orthopaedics, pediatrics, physiotherapy, psychiatry and social work. Medical experts from Brazil, a country greatly affected by Zika virus, are also members of the center.
Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. In their study, published in the peer-reviewed medical journal Cell, the investigators provide clues to unraveling some of the mysteries surrounding the human immune system, which defends the body against harmful microbes such as bacteria.
In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.
A chemical compound - new to science and never before identified - is being investigated by a graduate student who is working to replicate it so it can be tested as a weapon in the battle against disease-transmitting mosquitoes.
Researchers at the University of California, Davis, and in the Netherlands have discovered how three fungal diseases have evolved into a lethal threat to the world’s bananas.
Researchers at the University of Massachusetts Medical School have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy resistance.
University of Saskatchewan scientists at the Vaccine and Infectious Disease Organization International Vaccine Centre have developed and tested a prototype vaccine against Porcine Epidemic Diarrhea Virus (PEDV) which has so far killed more than eight million pigs and cost more than $400 million in lost income since 2013.
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