A recent genetic discovery has revealed that the pale grey plumage of the tawny owl is linked to crucial functions that aid the bird's survival in cold environments.
The discovery of a pair of genes that work in perfect harmony to protect male fertility, could provide new insights into some unexplained cases of the most severe form of infertility, research suggests.
Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.
Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field. The findings were published in the February 14 online issue of Cell. Utilizing data from more than 1,000 tumors across 10 different cancers, the study is the first to integrate DNA, RNA, and proteomics (the study of proteins), revealing the complex interplay of immune cells in tumors. The data came from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), a program under the National Cancer Institute.
Xiao Tian, Ph.D., who recently joined Sanford Burnham Prebys as an assistant professor in the Degenerative Diseases Program, focuses on epigenomic changes and deterioration that influence age-related diseases.
Argonne National Laboratory researchers have made new discoveries about the risks of prostate cancer in people with different genetic backgrounds.
Cedars-Sinai Guerin Children's inauguró hoy una clínica para ofrecer atención multidisciplinar especializada a niños con síndrome de Angelman, una enfermedad del neurodesarrollo rara y grave.
Cedars-Sinai Guerin Children’s opened a clinic today to provide specialized multidisciplinary care for children with Angelman syndrome, a rare and severe neurodevelopmental condition.
UT Southwestern Medical Center is partnering with Pfizer Inc. to develop RNA-enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center's Program in Genetic Drug Engineering.
Scientists hope to advance precision medicine through the discovery of a gene variant that leads to the same phenotype in separate high-dwelling populations while taking a different evolutionary path.
Biologists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory have demonstrated a new way to boost the oil content of plant leaves and seeds.
In a changing climate, corn growers need to be ready for anything, including new and shifting disease dynamics. Because it’s impossible to predict which damaging disease will pop up in a given year, corn with resistance to multiple diseases would be a huge win for growers.
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, “Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation.”
A pair of Iowa State University geneticists are among the first research teams in the world to construct DNA nanoparticles that can express their own built-in genetic instructions.
Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts.
To improve bioproducts productivity, researchers have engineered the genome of E. coli to make it immune to viral infections.
Russell DeBose-Boyd, Ph.D., Professor of Molecular Genetics at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research into a key mechanism necessary for cholesterol control.
A research study led by a multidisciplinary team of scientists at Roswell Park Comprehensive Cancer Center details evidence on the therapeutic efficacy of a compound that targets a key genetic feature of pancreatic cancer.
University of Queensland researchers have used machine learning to help predict the risk of secondary bacterial infections in hospitalised COVID-19 patients.
A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.
As the effectiveness of radiotherapy varies greatly between tumours, finding gene signatures to predict the radiation response could better guide the clinicians to personalize treatment plans.
Sydney and Sheridan Taylor of Durham, North Carolina, have lived with this rare genetic disorder all of their lives.
Fighting disease-causing bacteria becomes more difficult when antibiotics stop working.
Investigators in the Department of Computational Biomedicine at Cedars-Sinai wanted to find out which factors influenced susceptibility to COVID-19 infection and disease severity the most. Was it genetics? Or was it home environment, meaning the germs circulating throughout your everyday life?
Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function.
University at Albany scientist Scott Tenenbaum, founder of UAlbany spinoff company sxRNA Technologies, Inc. (sxRNA Tech), has received $500,000 from the National Institute on Aging, part of the National Institutes of Health, to study how aging brain cells shape the progression of Alzheimer’s disease, and advance RNA technology that could inform new therapeutics to prevent and treat Alzheimer's and related dementias.
Traditional genome editing faced limitations in achieving ultimate precision until now. Prof. Buchholz's team has broken through this barrier by creating what many have sought after: a zinc-finger conditioned recombinase.
Gliomas de alto grau são tumores cancerígenos que se espalham rapidamente no cérebro ou na medula espinhal.
الأورام الدبقية عالية الدرجة هي أورام سرطانية تنتشر بسرعة في الدماغ أو الحبل النخاعي. في دراسة جديدة أجريت تحت إشراف مايو كلينك، وجد الباحثون أن هوامش أورام الدماغ الغزوية للورم الدبقي عالي الدرجة تحتوي على تغيرات جينية وجزيئية مميزة بيولوجيًا تشير إلى السلوك العدواني وتكرار المرض. وتُظهر النتائج تصورات متعمقة للعلاجات المحتملة التي يمكن أن تحوّل مسار المرض.
Los gliomas de alto grado son tumores cancerígenos que se propagan rápidamente en el cerebro o en la médula espinal.
Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.
University Hospitals has been selected by the Global Parkinson’s Genetics Program as one of four new study sites for the Black and African American Connections to Parkinson’s Disease (BLAAC PD) study.
Pilot study by Children’s Hospital Los Angeles and City of Hope proposes a promising global, clinically applicable genomic assay for the diagnosis and treatment of this heterogeneous leukemia, reports The Journal of Molecular Diagnostics.
IU School of Medicine investigators and their collaborators in Uganda has revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia, which enhances strong evidence of hydroxyurea’s effectiveness and could ultimately reduce death in children in Africa.
Storb was a Professor in the Department of Molecular Genetics and Cell Biology for more than 29 years.
Legislation introduced in Illinois would eliminate financial barriers to clinically appropriate genetic testing and additional screenings in an effort to detect breast cancers related to a known inherited gene mutation.
The intricate dance of nature often unfolds in mysterious ways, hidden from the naked eye. At the heart of this enigmatic tango lies a vital partnership: the symbiosis between plants and a type of fungi known as arbuscular mycorrhizal (AM) fungi.
Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.
Pesquisadores da Mayo Clinic que estudam a genética de pessoas que recentemente desenvolveram cardiomiopatia dilatada (uma das causas mais comuns de insuficiência cardíaca), descobriram um gene particular para o qual o desenvolvimento de futuros tratamentos de terapia medicamentosa poderá ser direcionado.
Investigadores de Mayo Clinic que estudian la genética de personas que recientemente desarrollaron miocardiopatía dilatada, una de las causas más comunes de insuficiencia cardíaca, descubrieron que deben enfocarse en un gen particular para desarrollar tratamientos farmacológicos en el futuro.
Researchers at the Universities of Basel and Zurich have discovered the genetic material of the pathogen Treponema pallidum in the bones of people who died in Brazil 2,000 years ago.
Rutgers Health researcher develops software that can analyze multigenomic and clinical data to discover biomarkers and predict diseases in individuals.
IntelliGenes analyzes genomic data to discover biomarkers associated with health traits.
A newly published study provides guidance for building accurate mathematical models for gene regulatory networks. The project, which includes an online database, was supported by undergraduate researchers at Iowa State.
Sanjeev S. Ranade, Ph.D., who joined the faculty of Sanford Burnham Prebys this month as an assistant professor in the Development, Aging and Regeneration program, studies how proteins called transcription factors (TFs) specifically control the development and function of cardiac cells — and what happens when things go wrong.
Tumors constantly shed DNA from dying cells, which briefly circulates in the patient’s bloodstream before it is quickly broken down.
Analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma
An international team of researchers from McMaster University, University of Alaska Fairbanks and the University of Ottawa has tracked and documented the movements and genetic connections of a female woolly mammoth that roamed the earth more than 14,000 years ago.
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