New research published in the UEG Journal1 has found that Crohn's disease sufferers experience slower response times than matched individuals that do not have the disease.
There’s yet another reason to maintain a healthy weight as we age. An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma.
Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. In their study, published in the peer-reviewed medical journal Cell, the investigators provide clues to unraveling some of the mysteries surrounding the human immune system, which defends the body against harmful microbes such as bacteria.
The first published medical and surgical approach care plan for managing septic perianal Crohn’s disease, a serious complication that occurs in around 40 percent of Crohn’s disease patients has been developed by researchers at Penn State College of Medicine. The plan and its results took more than a decade to develop and are based on patient outcomes.
A recent study by researchers at the Atlanta Veterans Affairs Medical Center took them to a not-so-likely destination: local farmers markets. They went in search of fresh ginger root.
University of Helsinki researchers have previously demonstrated that a point mutation in a gene of serotonin 2B receptor can render the carrier prone to impulsive behaviour, particularly when drunk. Now the research group has established that the same mutation may shield its bearers from obesity and insulin resistance, both of which are associated with type 2 diabetes.
A new study by researchers at Emory's Rollins School of Public Health and the Centers for Disease Control and Prevention (CDC) shows that lifestyle modification programs modeled on diabetes prevention programs (DPP) trials not only achieved weight reduction, but also additional metabolic benefits -specifically, reductions in blood sugar, blood pressure, and cholesterol levels. The researchers compiled data from 44 published studies with nearly 9,000 adults participating in DPP conducted in US communities, clinics, and through online media.
Personalized Medicine Leads to Better Outcomes; Phase 1 Study Results of Selinexor Combination Therapy for Multiple Myeloma Patients; and the Latest from ASCO Sessions in the Cancer News Source
Researchers from Columbia University have found that people with non-celiac wheat sensitivity have a weakened intestinal barrier, which leads to a systemic immune response after ingesting wheat and related cereals.
Researchers have discovered a regulatory system in the ulcer- and stomach cancer-causing bacteria, Helicobacter pylori, that can control the formation of biofilm – a “fortress-like” cluster of cells that can become resistant to antibiotics and cause major medical problems.
Patients with irritable bowel syndrome (IBS) are often concerned that certain foods may trigger or worsen their symptoms, which can include abdominal pain, diarrhea, or constipation. In a new study, patients who ate rye bread that was low in so-called “FODMAPs” (fermentable oligo- di- and mono-saccharides and polyols) experienced milder IBS symptoms than patients who ate normal rye bread
Fecal transplants are increasingly being used to treat certain human illnesses and there is a major upsurge in animal experiments involving fecal material.
Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene.
Research from life scientists at The University of Manchester has shone new light on the way cells tune in to different inflammatory signals to understand what is happening in the body.
Low levels of the stress hormone cortisol are linked to obesity, high levels of fat in the blood and metabolic syndrome among patients with recurrent depressions or bipolar disorder. This according to a study at Umeå University in Sweden published in the Journal of Affective Disorders.
Persistent diarrhea, which is diarrhea that lasts at least 14 days, is an illness typically caused by parasites or bacteria and requires accurate diagnosis in order to determine what treatment to give, according to Herbert L. DuPont, M.D., director of the Center for Infectious Diseases at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.
Physicians have been mystified by chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn’t alleviated by rest. There are no known triggers, and diagnosis requires lengthy tests administered by an expert.
Now, for the first time, Cornell University researchers report they have identified biological markers of the disease in gut bacteria and inflammatory microbial agents in the blood.
An international team led by researchers at the Center for Sensorimotor Neural Engineering (CSNE) based at the University of Washington is one of three finalists in a race to produce an implantable wireless device that can assess, stimulate and block the activity of nerves that control organs.
Baylor Scott & White Research Institute scientists presented breakthrough findings at this year’s Digestive Disease Week® (DDW). DDW is the world’s largest and most prestigious gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
Dr. David E. Cohen, an internationally renowned physician-scientist who combines clinical care as a hepatologist with research focused on obesity-related liver disease, has been named chief of the Division of Gastroenterology and Hepatology at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center, effective July 1.
“It’s the diarrhea that can kill you,” noted professor emeritus David Francis, an expert on colibacillosis, an intestinal disease that affects newborn and weanling pigs. The toxin-producing E. Coli bacterium that causes the swine disease is similar to the organism responsible for traveler’s diarrhea in humans. Francis will speak at the 24th International Veterinary Conference in Dublin, Ireland, June 7-10.
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Intestinal stem cells are located in “pockets” in the intestine to avoid contact with a metabolite abundantly produced by normal gut microbes. That metabolite – butyrate – suppresses stem cell proliferation, potentially interfering with the gut’s ability to repair itself after disease or injury.
• In patients with chronic kidney disease, those with more advanced disease had higher blood levels of the bacterial metabolite phenylacetylglutamine.
• Patients with high phenylacetylglutamine had an elevated risk of developing cardiovascular disease as well as a heightened risk of dying prematurely.
A new study suggests that triclosan, an antimicrobial and antifungal agent found in many consumer products ranging from hand soaps to toys and even toothpaste, can rapidly disrupt bacterial communities found in the gut.
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Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research (early online), an American Heart Association journal. This accelerated aging in humans could lead to increased cardiovascular disease, vascular dementia and renal failure.
A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.
Years before inflammatory bowel disease (IBD) is diagnosed and symptoms exist, biomarkers are already circulating that can help predict risk not only of disease development but also of complications.
Pinellas County a Model for Mosquito-Borne Disease Surveillance, Scientists Unravel the Genetic Evolution of Zika Virus, Worm Infection Counters Inflammatory Bowel Disease and more in the Infectious Diseases News Source
A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body, according to researchers at Georgia State University.
Columbia University researchers have found evidence in mice that, for some types of autism, gastrointestinal problems may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition.
An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe. The study is published in the Scientific Reports.
Researchers at UMass Medical School have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. This finding, based on studying calcium ion-controlled pathways in mice, may lead to new treatments for a host of digestive disorders ranging from common gastroesophageal reflux disease (GERD), to swallowing disorders, incontinence and pancreatitis. Details of the study were published in Nature Communications.