Feature Channels: Transplantation

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妙佑医疗国际(Mayo Clinic) 致力于开发和完善各种再生医疗程序，以帮助患者为器官移植做好准备。这些再生医疗程序为器官移植患者提供了新的选项，让他们能够在等待生命的馈赠期间积极增强体质并恢复健康。

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Mayo Clinic no solamente va a la vanguardia de los procedimientos regenerativos que sirven como puente al trasplante, sino que también los refina. Estos procedimientos brindan nuevas alternativas para recuperar y fortalecer la salud, mientras los pacientes esperan que llegue ese regalo de vida.

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UCLA researchers presented today the first case of a U.S. woman living with HIV-1 that is in remission after she received a new combination of specialized stem cell transplants for treatment of acute myeloid leukemia (AML). The oral abstract was presented at CROI 2022, the Conference on Retroviruses and Opportunistic Infections.

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Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.

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New Jersey Woman Gives the Gift of Life to Her Spouse this Valentine's Day

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The Johns Hopkins Health System will no longer use a long-standing clinical standard that factors a patient’s race into kidney function tests.

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Mayo Clinic and Carnegie Mellon University (CMU) announced today a research agreement to transform organ transplantation. The institutions will bioengineer innovative approaches to address barriers in organ transplantation.

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While balancing the demands of the COVID-19 pandemic, the team at Baylor Scott & White Medical Center – Temple was able to successfully help nearly 200 patients receive a life-changing organ transplant last year. From January through December 2021, 191 abdominal transplant procedures were conducted, a new record for the hospital and a 25% increase from its previous record set in 2017.

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Diagnosed with acute liver failure and her health rapidly deteriorating, it seemed like 11-month-old Lennon would need a miracle to survive. Thanks to a team of specialists at Children’s Hospital Los Angeles, she just celebrated her third birthday.

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For many COVID-19 patients with irrecoverable lung damage, transplantation is the only option for survival. However, there is limited information about the long-term outcomes of these patients, including postoperative complications, hospital length of stay and survival. A new study published in the Journal of the American Medical Association (JAMA) shows positive outcomes in the first 30 consecutive COVID-19 patients who underwent a lung transplant at Northwestern Medicine in Chicago.

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Un estudio de Mayo Clinic recientemente publicado afirma que el mayor riesgo para los receptores de un trasplante renal no es el rechazo del órgano, sino el cáncer, las infecciones y las enfermedades cardíacas.

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Amid the uncertainty of the ongoing COVID-19 pandemic, the Cedars-Sinai Comprehensive Transplant Center and Smidt Heart Institute together completed 573 solid organ transplants in 2021, surpassing 2020’s count of 529 and achieving a new record for the medical center.

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câncer, infecções e doença cardíaca representam os maiores riscos para as pessoas que recebem um transplante de rim, e não a rejeição do órgão, de acordo com um estudo da Mayo Clinic publicado recentemente.

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根据最近发表的一项妙佑医疗国际(Mayo Clinic)研究，对肾移植受者危害最大的是癌症、感染和心脏病，而不是器官排斥。研究人员发现，由于器官排斥以外的因素导致的受者死亡是移植肾丢失的主要原因。只有1/4的移植肾丢失是由器官排斥造成的。

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Cardiothoracic surgeons in the Smidt Heart Institute at Cedars-Sinai recently performed a groundbreaking robotic-assisted lung transplant.

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Throughout the month of February—American Heart Month—the Cedars-Sinai Newsroom will highlight new research, heart-health recommendations and clinical and surgical advances. Experts from the Smidt Heart Institute at Cedars-Sinai, home to California’s top heart and heart surgery programs, are available to address these timely heart-related topics.

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A Smidt Heart Institute analysis of lung transplantations performed nationally shows significant help for patients with severe, irreversible lung damage from COVID-19.

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The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current clinical advances include combination therapies for thyroid cancer and multiple myeloma, as well as discoveries to improve CRISPR/Cas9 gene editing, to identify biomarkers for immunotherapy response, to utilize T cell therapy for osteosarcoma and to understand of the role of LIP-1 in regulating ERK signaling.

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A record-high 346 organ transplants were done at the University of Chicago Medicine in 2021 — up 42% from the previous year and part of a nationwide trend in transplant surgeries.

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For the first time, University of Utah Health scientists have shown that artificial intelligence could lead to better ways to predict the onset and course of cardiovascular disease.

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Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows that a partial bone marrow transplant helps these mice by introducing a population of healthy immune cells called monocytes.

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Cancer, infections and heart disease pose the greatest risk to kidney transplant recipients ― not organ rejection ― according to a recently published Mayo Clinic study. Researchers discovered that recipient death due to factors other than organ rejection is the leading cause for transplanted kidney loss. Only 1 in 4 transplanted kidney losses were caused by organ rejection.

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The Cedars-Sinai Cancer Blood & Marrow Transplant Program’s one-year patient survival rate exceeded expectations compared to transplant centers in the U.S. whose similar patients underwent allogeneic transplants, according to a national report that tracks those outcomes.

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A critical shortage of blood, which has stretched supplies thin nationwide, threatens hospitals' ability to provide many types of patient care. The Red Cross has just declared the first-ever national blood crisis. A blood bank director with nearly 40 years of experience urges every eligible person to step up and make an appointment to donate as soon as possible.

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Loyola Medicine experts have concluded that COVID-19 vaccine requirements for lung transplant patients are an ethical and necessary practice. Daniel Dilling, MD, medical director of the lung transplantation program at Loyola Medicine, and Mark Kuczewski, PhD, a professor of medical ethics at the Stritch School of Medicine, shared their recommendation in a paper published by the Journal of Heart and Lung Transplant.

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A new analysis of national kidney transplant and organ discard data concludes that too many deceased donor organs with acute kidney injury (AKI) may be needlessly going to waste because of a change in the way kidneys are evaluated.

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In the future, mass transportation will almost certainly involve self-driving vehicles. The aerospace industry is pushing that idea even further, all the way to space. Now, a Cornell University project that demonstrates the technology’s potential is poised to take flight.

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In a first-of-its-kind surgery, a 57-year-old patient with terminal heart disease received a successful transplant of a genetically-modified pig heart and is still doing well three days later. It was the only currently available option for the patient.

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New NCCN Guidelines for Patients: Graft-Versus-Host Disease offers clarity and consensus on how best to address and treat a common and complex immune response side-effect from stem cell transplants.

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With an $8 million grant from the National Institutes of Health (NIH), the next stage of the THINKER project — called THINKER-NEXT — will aim to provide a comprehensive view of the risks and benefits of transplanting HCV-infected kidneys into non-infected patients.

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Kidney transplants from deceased donors function for a median of 10 to 15 years. New research indicates that when a kidney transplant fails, retransplantation may offer better survival patients compared with undergoing dialysis.

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On a recent Saturday, Gerald Freeny got a sneak peek at a few of this year’s Rose Parade floats being decorated by volunteers at a warehouse in Irwindale, California. The behind-the-scenes look captivates many, but it isn’t new to Freeny. He comes here, year after year, as part of his role as a member of the Tournament of Roses Association.

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Penn Medicine has been awarded a prestigious seven-year, $14 million grant from the National Institutes of Health (NIH) to promote organ transplantation for patients with end-stage renal disease who are currently on the waitlist for a kidney transplant. The team will launch a clinical trial harnessing synthetic chimeric antigen receptor (CAR) T cells – a form of which was developed at Penn Medicine and became the first personalized cellular therapy for cancer – for use in patients for whom a compatible kidney cannot be found due to pre-existing antibodies against potential donors.

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A drug combination can safely prevent transplanted stem cells (graft) from attacking the recipient’s (host) body, allowing them to develop into healthy new blood and immune cells, a new study shows.

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How two of UC San Diego Health’s record-breaking 81 heart transplant recipients in 2021 forged a unique bond of mutual support.

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Patients whose immune systems are weakened due to cancer, organ or bone marrow transplants, chronic diseases, or the medications used to treat these conditions may feel like they have enough on their plates without worrying about whether and when they should take an additional dose of COVID-19 vaccine and a flu shot.

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University of Maryland Medicine, comprised of the University of Maryland Medical System (UMMS) and the University of Maryland School of Medicine (UMSOM) has announced that it will end the use of a long-standing clinical standard that factors a patient’s race into the diagnosis of chronic kidney disease (CKD).

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University of Maryland Medicine will end use of a long-standing clinical standard that factors a patient’s race into the diagnosis of chronic kidney disease. The change could increase access to specialty care including transplant for thousands of Black people living with advanced kidney disease.

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Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging. When looking for appropriate stem cell/bone marrow donors, clinicians tend to stay away from older donors with clonal hematopoiesis (CH) because of concerns about passing potentially premalignant stem cells to the recipient.

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Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

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Patients with a rare immunodeficiency disorder who are treated with lifelong immunoglobulin replacement therapy (IRT) have a lower risk of premature death than patients treated with a hematopoietic stem cell transplant (HSCT), but they also have a reduced quality of life and must assume a substantial financial burden, according to a new study led by Children’s Hospital of Philadelphia (CHOP). Using a computational model to calculate the costs and benefits of IRT and HSCT for patients with agammaglobulinemia, the researchers concluded that the high cost of IRT in the U.S. undermines its cost-utility, particularly when compared to Canada and European countries, where the cost of IRT is nearly a third of what it is in the U.S.

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Loyola Medicine has completed Illinois' first heart transplant using a newly developed cardiac transport system. The Paragonix SherpaPak® System aims to change the way hearts are transported during transplant, utilizing a canister that monitors temperature rather than packing the heart in ice.

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ALEXANDRIA, Va. – A new study has found that people with nonalcoholic fatty liver disease (NAFLD) cirrhosis who are not overweight and are on a waiting list for a liver transplant fare worse than overweight patients before and after transplant surgery. The study concludes that these at-risk patients need better nutritional counseling and other interventions to help prevent serious health problems while they are waiting for liver transplant.

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ALEXANDRIA, Va. – A new study has found that the proportion of older Americans who need a liver transplant (LT) has sharply increased in recent years, often due to the rising number of cases of nonalcoholic steatohepatitis (NASH). As the U.S. population ages, researchers estimate that more patients aged 65 or older will need an LT than ever before.