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Released: 8-Jan-2019 9:05 PM EST
Let’s map our DNA and save billions each year in health costs
University of South Australia

A University of South Australia scientist has called for Australia to embrace pharmacogenetic (PGx) testing to deliver medication more effectively and slash around $2.4 billion wasted each year through unsafe and ineffective drug prescriptions.

Released: 8-Jan-2019 5:05 PM EST
American Society of Anesthesiologists Hosts PRACTICE MANAGEMENT™ 2019
American Society of Anesthesiologists (ASA)

The American Society of Anesthesiologists (ASA) will host PRACTICE MANAGEMENT™ 2019, Jan. 18-20, in Las Vegas. The three-day meeting will bring together leaders and subject-matter experts in anesthesia to share new research, knowledge and critical skills needed to optimize an anesthesiology practice’s performance.

Released: 8-Jan-2019 4:05 PM EST
Case Western Reserve’s John “Chip” Tilton, MD, Secures School of Medicine’s Fourth Falk Catalyst Award
Case Western Reserve University

John “Chip” Tilton, MD, of Case Western Reserve University School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton’s project will address a major challenge in developing nanoscale therapeutics: finding ways to deliver them to the right location inside the body.

Released: 8-Jan-2019 3:35 PM EST
Estudio sobre células senescentes pasa a ensayos clínicos
Mayo Clinic

Los investigadores de Mayo Clinic junto con otros colaboradores de la Escuela de Medicina de la Universidad de Wake Forest y del Centro de Ciencias de la Salud de la Universidad de Texas en San Antonio publicaron los resultados de un ensayo clínico sobre la seguridad y la factibilidad de extraer células senescentes en un pequeño grupo de pacientes con fibrosis pulmonar.

Released: 8-Jan-2019 2:05 PM EST
First-in-Class DNA-encoded Monoclonal Antibody Therapy Rapidly Advances into the Clinic
Wistar Institute

Wistar, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc. announce the FDA has approved the initiation of a first-in-human clinical trial investigating safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody (DMAb) therapeutic technology for the prevention of Zika virus infection.

   
Released: 8-Jan-2019 1:35 PM EST
Variable venom -- why are some snakes deadlier than others?
Trinity College Dublin

An international collaboration led by scientists from the National University of Ireland, Galway, The University of St Andrews, Trinity College Dublin and the Zoological Society of London has uncovered why the venom of some snakes makes them so much deadlier than others.

Released: 8-Jan-2019 1:05 PM EST
Top University of Maryland School of Medicine Genomics Scientist Claire M. Fraser, Phd, Appointed President-Elect of AmericanAssociation for the Advancement of Science (Aaas)
University of Maryland School of Medicine

University of Maryland School of Medicine (UMSOM) Dean E. Albert Reece, MD, PhD, MBA, announced today that Claire M. Fraser, PhD, a pioneer in the field of microbial genomics, who is the Dean’s Endowed Professor, Department of Medicine, and Director of the Institute for Genome Sciences (IGS), has been chosen as president-elect of the American Association for the Advancement of Science (AAAS).

   
8-Jan-2019 9:45 AM EST
Stroke drug may also prevent Alzheimer’s disease, say USC researchers
The Rockefeller University Press

Researchers from the University of Southern California have discovered that a drug currently being developed to treat stroke patients could also prevent Alzheimer’s disease. The study, which will be published January 15 in the Journal of Experimental Medicine, shows that the genetically engineered protein 3K3A-APC protects the brains of mice with Alzheimer’s-like symptoms, reducing the buildup of toxic peptides and preventing memory loss.

3-Jan-2019 12:05 AM EST
Rising Drug Prices Linked to Older Products, Not Just Newer, Better Medications
Health Sciences at the University of Pittsburgh

Pharmaceutical companies often cite R&D as the driver behind rising drug costs, but a new analysis shows that price inflation on older drugs is to blame.

   
Released: 7-Jan-2019 3:05 PM EST
MD Anderson Cancer Center and Nanobiotix announce a large-scale, comprehensive clinical collaboration on NBTXR3
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and Nanobiotix today announced a large-scale, comprehensive clinical research collaboration to evaluate innovative strategies for treating patients with head and neck, pancreatic, thoracic, lung, gastrointestinal and genitourinary cancers, with the first trials to be launched in 2019.

Released: 7-Jan-2019 11:00 AM EST
Senescent cell research moves into human trials
Mayo Clinic

Rochester, Minn. — Mayo Clinic researchers, along with collaborators from Wake Forest School of Medicine and the The University of Texas Health Sciences Center at San Antonio, have published findings from a safety and feasibility clinical trial on the removal of senescent cells from a small group of patients with pulmonary fibrosis. The findings appear in EBioMedicine.

Released: 7-Jan-2019 10:05 AM EST
First-in-human trial of senolytic drugs encouraging
Atrium Health Wake Forest Baptist

UT Health San Antonio researchers, collaborating with the Mayo Clinic and the Wake Forest School of Medicine, are the first to publish results on the treatment of a deadly age-related disease in human patients with drugs called senolytics. The findings were posted Jan. 4 by the journal EBioMedicine, which is published by The Lancet.

Released: 7-Jan-2019 10:05 AM EST
Researchers make important discovery for ‘smart’ films and encapsulation
University of Notre Dame

New study from Notre Dame has found that the properties of a material commonly used to create conductive or protective films and encapsulate drug compounds – and the conditions in which this material will disassemble to release that medication – may be different than initially thought.

Released: 7-Jan-2019 10:05 AM EST
Henry Ford Cancer Institute Enrolls First Patient in Pancreatic Cancer Research Study
Henry Ford Health

The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat pancreatic cancer.

Released: 7-Jan-2019 9:50 AM EST
Opioids Fueled a Doubling of Suicides and Overdoses in the U.S.
Michigan Medicine - University of Michigan

Suicides and drug overdoses kill American adults at twice the rate today as they did just 17 years ago, and opioids are a key contributor to that rise, according to a new review and analysis. Reversing this deadly double trend will take investment in programs that have been proven to prevent and treat opioid addiction, the researchers say.

Released: 7-Jan-2019 9:50 AM EST
New Jersey Public Health Laboratory Collaboration with Rutgers Is a Win-Win for Both
Rutgers Robert Wood Johnson Medical School

Rutgers Robert Wood Johnson Medical School and the New Jersey Department of Health formalized a partnership that brought a member of the medical school’s faculty in as medical director of the laboratory. The lab oversees clinical diagnostic and surveillance testing; improvement service, which handles inspections and protocol compliance; and testing drinking water and groundwater, as well as handling environmental evaluations of pollutants, toxins, and heavy metals. Te director also supervises the testing of medicinal marijuana.

Released: 7-Jan-2019 9:45 AM EST
Personalized vaccine to be tested for the first time in patients with kidney cancer
Dana-Farber Cancer Institute

By pairing a novel personalized cancer vaccine with a more established immunotherapy drug that is administered to patients in an innovative fashion, scientists at Dana-Farber Cancer Institute are testing a first-of-its-kind strategy aimed at improving outcomes for kidney cancer patients who are at high risk of recurrence following surgery.

5-Jan-2019 4:05 PM EST
MD Anderson Cancer Center and Ascentage Pharma announce strategic alliance in cancer drug development
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and Ascentage Pharma Group, Inc. today announced a five-year strategic collaboration agreement to advance the development of five potential new cancer therapies.

Released: 4-Jan-2019 11:05 AM EST
Neurocritical Care Expert Leads NYU Langone Hospital–Brooklyn’s Sophisticated Stroke and Neurology Programs
NYU Langone Hospital - Brooklyn

Aaron S. Lord, MD, will lead a program that already has been recognized for national clinical excellence. NYU Langone Hospital–Brooklyn is one of the few hospitals in the country to hold dual certification by The Joint Commission as both a Comprehensive Stroke Center and Stroke Rehabilitation Center.

31-Jan-2019 4:45 PM EST
The Dangers of Hidden Fat: Exercise Is Your Best Defense Against Deep Abdominal Fat
UT Southwestern Medical Center

Researchers analyzed two types of interventions – lifestyle modification (exercise) and pharmacological (medicine) – to learn how best to defeat fat lying deep in the belly.

2-Jan-2019 3:05 PM EST
Study Shows New Way to Group Protein Kinases as Cancer Drug Targets
Stony Brook University

A new study published early online in Cell Chemical Biology led by Markus Seeliger, PhD, Associate Professor of Pharmacological Sciences in the Renaissance School of Medicine at Stony Brook University, takes a fresh approach to grouping kinases as potential drug targets.

Released: 3-Jan-2019 11:05 AM EST
UAB outsources its revenue-producing antibodies to the Birmingham company SouthernBiotech
University of Alabama at Birmingham

In a move to maintain revenue and expand opportunities to produce and license new monoclonal antibodies, UAB has outsourced its selection of marketable monoclonal immunoreagents and hybridomas — the cells that produce monoclonal antibodies — to the Birmingham-based SouthernBiotech.

Released: 3-Jan-2019 8:00 AM EST
Technology and Doctors Combine to Detect Patients Who Don’t Take Their Pills
Johns Hopkins Medicine

Johns Hopkins researchers have shown how to best identify nonadherent patients, combining technology with the perceptions of health care providers.

21-Dec-2018 8:05 AM EST
Pre-Medicare years bring health insurance worries for many, U-M/AARP poll finds
Michigan Medicine - University of Michigan

With the dawn of a new year, most Americans have just started a new health insurance coverage period -- whether they receive their coverage through a job, buy it themselves or have a government plan.

2-Jan-2019 3:30 PM EST
New Study Shows Disparities in EDX Training in Residency Programs
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

Results from a 2017 survey shared at the 2018 AANEM Annual Meeting illustrate significant disparities in the amount of training that neurology and physical medicine and rehabilitation (PMR) residents receive in electrodiagnostic (EDX) medicine.

1-Jan-2019 8:05 AM EST
A Proposal to Correct Minority Underrepresentation in Clinical Trials
University of Kentucky

A neurologist takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

Released: 2-Jan-2019 10:05 AM EST
Painful Intercourse in Women Improved with Fibromyalgia Drug, Rutgers Study Says
Rutgers University-New Brunswick

Study suggests that the oral medication Gabapentin can reduce pain and increase sexual desire and satisfaction

Released: 2-Jan-2019 10:05 AM EST
ASA Commends HHS Pain Taskforce Recommendations to Address Safe Opioid Use and Multimodal Approaches to Control Pain
American Society of Anesthesiologists (ASA)

Today, the American Society of Anesthesiologists (ASA) applauded the U.S. Department of Health and Human Services (HHS) Pain Management Best Practices Interagency Task Force on the release of draft acute and chronic pain management best practice recommendations, many of which align with solutions presented and advocated by ASA.

2-Jan-2019 6:00 AM EST
Got Research in Neuromuscular/Electrodiagnostic Medicine? Submit Abstracts for the 2019 AANEM Annual Meeting by March 15
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

If you’re looking for the perfect venue to share your scientific research in neuromuscular or electrodiagnostic medicine, look no further! The American Association of Neuromuscular & Electrodiagnostic Medicine is now accepting abstracts for its 2019 annual meeting in Austin, Texas.

Released: 1-Jan-2019 10:05 PM EST
New Penn State Health facility expands access to primary and specialty care in Lancaster County
Penn State Health

A new Penn State Health facility gives Lancaster County residents more convenient access to primary and specialty care close to home. Penn State Health Medical Group – Lime Spring Outpatient Center, the health system’s newest, most comprehensive clinic, welcomed its first patients on Wednesday, Jan. 2.

Released: 27-Dec-2018 1:05 PM EST
Rheumatology Community Urges CMS to Proceed with Caution When Considering IPI Drug Pricing Model
American College of Rheumatology (ACR)

– In comments submitted to the Centers for Medicare and Medicaid Services (CMS), the American College of Rheumatology (ACR) urged the agency to proceed with caution when considering the International Pricing Index (IPI) drug pricing model, which was announced in an Advance Notice of Proposed Rulemaking in October.

Released: 27-Dec-2018 12:00 PM EST
How Can Palliative Medicine Help with End-of-Life Decisions?
Ohio State University Wexner Medical Center

It’s never too early to start thinking about end-of-life decisions. The palliative care team can help guide this discussion to learn more about the patient’s values, goals and preferences, which can help clarify these end-of-life decisions.

Released: 21-Dec-2018 11:05 AM EST
Department of Defense Awards CWRU Researcher Nearly $1M to Study Prostate Cancer Drug Resistance
Case Western Reserve University

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer. The funding is part of the Department of Defense’s Idea Award program, that aims to improve quality of life by decreasing the impact of cancer on active duty service members and their communities. Gupta will use the award and clinically-approved drugs to develop a safe, efficacious, and cost-effective combination therapy for castrate-resistant prostate cancer.

Released: 20-Dec-2018 5:00 PM EST
Scientists at the Forefront of Alternative Toxicological Methods, Pharmaceutical Safety, the Effects of Environmental Exposures on Genetics, and More Recognized with 2019 SOT Awards
Society of Toxicology

The Society of Toxicology (SOT) is pleased to announce the recipients of its 2019 awards. The awardees include early-career scientists to groundbreaking researchers who have impacted the field for many years.

Released: 20-Dec-2018 2:05 PM EST
Individuals with Slower Ibuprofen Metabolism Can Self-adjust Dosage
Coriell Institute for Medical Research

New research from scientists at the Coriell Institute for Medical Research shows that some individuals whose bodies metabolize ibuprofen more slowly – causing the drug to be present at higher levels than intended – intuitively self-correct their dose without knowing their genetic makeup.

Released: 20-Dec-2018 7:00 AM EST
Nuclear Medicine? It’s Probably Not at All What You Think It Is
Atrium Health Wake Forest Baptist

The often-misunderstood specialty employs low doses of radioactive materials and advanced imaging technologies to diagnose and treat a variety of diseases.

Released: 19-Dec-2018 11:05 AM EST
Edging Closer to Personalized Medicine for Patients with Irregular Heartbeat
Washington University in St. Louis

Biomedical engineer Jon Silva led an international team that determined which patients would benefit the most from a commonly used drug treatment.

Released: 18-Dec-2018 5:05 PM EST
La Jolla Institute for Immunology renews longtime collaboration with Kyowa Kirin Pharmaceutical Research, Inc.
La Jolla Institute for Immunology

La Jolla Institute for Immunology (LJI) and Kyowa Kirin Pharmaceutical Research, Inc. (KKR), a wholly-owned subsidiary of Kyowa Hakko Kirin Co., Ltd. (KHK), a global specialty pharmaceutical company, today announced the signing of a new agreement. The agreement extends the longest industry-academic collaboration in the world for another three-year term, through until the end of 2021.

Released: 18-Dec-2018 5:05 PM EST
UM School of Pharmacy-led Team to Aid FDA in Examining Clinical Need for Compounding Using Bulk Drug Substances
University of Maryland, Baltimore

Ashlee Mattingly, PharmD, BCPS, assistant professor at the University of Maryland School of Pharmacy, will collaborate with leaders of the University of Maryland Center of Excellence in Regulatory Science and Innovation (M-CERSI).

Released: 18-Dec-2018 12:05 PM EST
Neutron micelle measurements lend insights into improved drug delivery
Oak Ridge National Laboratory

Researchers from the University of Houston are using neutron scattering at ORNL to research how unique biological structures known as micelles can make drugs more effective. Micelles can form around drug molecules in order to transport them through the human body. To make micelles better at transporting these molecules, the researchers are investigating how micelles are affected by the molecules they transport.

Released: 18-Dec-2018 12:05 PM EST
Dr. Steve Goldstein named UCI vice chancellor for health affairs
University of California, Irvine

Irvine, Calif., Dec. 18, 2018 — Dr. Steve Goldstein – a nationally renowned academic leader, physician and pediatric researcher – has been named vice chancellor for health affairs at the University of California, Irvine, effective Feb. 1, 2019. Goldstein will oversee and guide the development of the Susan and Henry Samueli College of Health Sciences, formed last year with a cornerstone gift of $200 million, the largest in UCI’s history.

Released: 18-Dec-2018 11:55 AM EST
Widespread, occasional use of antibiotics in US linked with resistance
Harvard T.H. Chan School of Public Health

The increasing prevalence of antibiotic resistance in the U.S. appears more closely linked with their occasional use by many people than by their repeated use among smaller numbers of people, according to a large new study from Harvard T.H. Chan School of Public Health.

Released: 18-Dec-2018 11:05 AM EST
UC San Diego Health Offers New Bluetooth-Enabled “Pacemaker” for Chronic Focal Nerve Pain
UC San Diego Health

After living with debilitating phantom leg pain for 18 years, Raul Silva is excited about a new dorsal root ganglion (DRG) stimulation device that erased his pain during a testing phase at UC San Diego Health, one of the only health care providers in the region offering the device.

Released: 18-Dec-2018 10:05 AM EST
Trial May Uncover New Diagnostics and Treatment Option for Cardiovascular Disease
Wayne State University Division of Research

A Wayne State University research team, in collaboration with Arterez, LLC, a Michigan-based biopharmaceutical company, has commenced a clinical study to identify the “fingerprint” and diagnostic accuracy of Arterez’ seven patent-pending glycocalyx biomarkers in relation to arterial disease, specifically hypertension and heart failure.

Released: 18-Dec-2018 7:05 AM EST
Estimating the Timing of Future Generic Drug Entry: Study Reports Accuracy of New Prediction Method
ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of new research describing a method to predict generic entry of top-selling drugs and a formal assessment of its accuracy.

Released: 18-Dec-2018 2:05 AM EST
Update on Drug Policies in Central and Eastern Europe
ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health Regional Issues, the regionally focused online journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of a series of 4 articles describing current drug policy in Estonia, Romania, Greece, and the Russian Federation.

Released: 17-Dec-2018 1:05 PM EST
The Keck School of Medicine of USC appoints chair of Department of Family Medicine
Keck Medicine of USC

The Keck School of Medicine of USC appoints skilled physician as chair of Department of Family Medicine



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