Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development

Wang and colleagues comprehensively compare the landscapes of H3K9me3 between human and mouse early embryos and reveal the roles of hominoid-specific retrotransposons in H3K9me3-dependent heterochromatin remodeling during early human development. Their study indicates that the epigenetic regulation for early development quickly evolve in mammals.