Newswise — CHICAGO, July 1, 2015 -- Sleep disruption appears to be associated with altered pain processing and central sensitization, according to research reported in The Journal of Pain, published by the American Pain Society, www.americanpainsociety.org.
In patients with osteoarthritis (OA), more than half experience pain during the night, resulting in sleep disruption, poor sleep quality, sleep fragmentation and frequent shifts between sleep stages. Recent studies have shown that sleep disruption can be a predictor of pain severity. Sleep disruption, therefore, could be associated with increased pain sensitivity and enhanced pain facilitation in addition to reduced pain inhibition in persons with chronic pain.
A team of researchers from Arizona State University, University of Alabama and University of Florida analyzed the relationships of self-reported insomnia severity and maladaptive sleep behaviors with pain sensitivity in persons with knee osteoarthritis (OA). They hypothesized that reports of greater insomnia severity would be associated with lower pain thresholds and inhibition and with greater temporal summation of pain.
For the study, participants with knee pain were recruited from the community with eligibility being age 45 to 85, African American or non-Hispanic white and knee OA based on American College of Rheumatology criteria. Subjects completed sleep questionnaires and experimental pain applications.
Results showed that severity of sleep disruption were associated with altered pain processing, and that sleep interventions for persons with knee OA-related pain might contribute to pain reductions. The authors noted that cognitive-behavioral therapies focused on sleep may have the most significant benefits for improving sleep in patients with insomnia and OA pain.
About the American Pain Society Based in Chicago, the American Pain Society (APS) is a multidisciplinary community that brings together a diverse group of scientists, clinicians and other professionals to increase the knowledge of pain and transform public policy and clinical practice to reduce pain-related suffering. APS is the professional home for investigators involved in all aspects of pain research including basic, translational, clinical and health services research to obtain the support and inspiration they need to flourish professionally. APS strongly advocates expansion of high quality pain research to help advance science to achieve effective and responsible pain relief. For more information on APS, visit www.americanpainsociety.org.
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