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Lancet 2004; 363: 1285-86
Newswise — Researchers from Taiwan report the identification of a new form of drug-resistant salmonella bacterium in this week's issue of THE LANCET.
Salmonella enterica serotype choleraesuis usually causes infections that require antimicrobial treatment. Multidrug-resistant strains have been identified, but the antimicrobial ceftriaxone has been effective against them so far.
Professor J T Ou, from Chang Gung University College of Medicine, Taoyuan, Taiwan, and colleagues isolated a strain of Salmonella enterica serotype choleraesuis that was resistant to all antimicrobials commonly used to treat salmonellosis, including ceftriaxone and ciprofloxacin. The bacterium came from a 58-year-old man with sepsis who subsequently died.
The drug-resistance was due to changes in the genes of the bacteria, including some in a genetic element that can potentially be transmitted between bacteria. Although this strain was from only one patient, the public-health implications of multidrug-resistant salmonella are serious. "Constant surveillance is needed to prevent its further spread," warn the authors.
Please remember to cite The Lancet.
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