High-Power Prismatic Devices May Further Expand Visual Fields for Patients with Hemianopia

Impairing either the left or right halves of the visual fields in both eyes, hemianopia affects more than one million Americans and is most commonly caused by stroke, brain tumors and head trauma. Hemianopia reduces the natural visual field of about 180 degrees to a mere 90 degrees. People with hemianopia have difficulty detecting hazards on their blind sides, leading to collisions, falls and other accidents. Patients with hemianopia cannot legally drive in Massachusetts, where a visual field of 120 degrees is required.

One method of treatment for hemianopia is to expand the visual field with prisms mounted on or embedded in eyeglasses. A research team led by Eli Peli, M.Sc., O.D., FAAO, Professor of Ophthalmology at Harvard Medical School and the Moakley Scholar in Aging Eye Research at the Schepens Eye Research Institute of Mass. Eye and Ear, has been developing prism devices to expand the visual field for these patients for more than 15 years. Their most recent commercially available device introduced in 2013, the peripheral prism glasses, has been shown to expand the visual fields of patients with hemianopia by as much as 30 degrees, optically shifting objects from the blind side of the visual field to the seeing side.

With the goal of expanding the visual field on the blind side even farther, the researchers explored new optical techniques to create higher power image shifting devices designed to bend the light farther than the 30-degree limit of conventional prisms. In conventional prisms, increasing the angle eventually results in the light bending back into the prism, trapped by what is called “total internal reflection.”

“It’s not just that we need a device with a higher angle of light shifting to let them see farther,” said Dr. Peli. “We also want the new devices to provide the additional range of vision when the patient scans their eyes in both directions. The current prism devices support such flexibility only when scanning into the seeing side.”

The authors introduced three new high-power prism concept devices in the Optometry and Vision Science paper:

Yoked Prisms in the Carrier LensBy embedding the current prism in a spectacle lens that has prismatic power in the opposite direction, the image shifting effect is increased by the summation of the power of both prism types. This design allows for up to 36 degrees of expansion to the visual field on the patient’s blind side. This design permits 5 degrees of scanning range to the blind side with full effect.

Bi-Part Double Fresnel PrismTo increase the power of the peripheral prism, the bi-part double Fresnel prism combines two prism segments angled to each other. This design allows for up to 43 degrees of expansion to the visual field on the patient’s blind side and an increase to 14 degrees scanning range into the blind side.

Mirror-Based Periscopic PrismThe third approach – not yet fully manufactured – uses a pair of angled mirrors to deflect the image from the blind side to the seeing side – not unlike prism correction. Due to the mirror-based design, this device is distortion-free and does not suffer from the color splitting effect of prisms, which reduces image clarity. It may allow for up to 40 degrees of expansion to the visual field on the patient’s blind side with much wider scanning range permitted.

The researchers intend to fully design and implement the mirror-based periscopic prism and also begin testing all three designs in patients with hemianopia.

“The new optical devices can improve the functionality of the current prism devices used for visual field expansion and may find use in various other field expansion applications such as a mobility aid for patients with tunnel vision,” Dr. Peli said.

Authors on the Optometry and Vision Science paper include Dr. Peli, Alex Bowers, Ph.D., MCOptom, FAAO, and Jae-Hyun Jung, Ph.D., of the Schepens Eye Research Institute of Massachusetts Eye and Ear/Harvard Medical School, and Karen Keeney, M.S from Chadwick Optical.This research study was supported in part by NIH grants R01EY12890 and R01EY23385, R00EY018680 and R44EY014723.

About Massachusetts Eye and EarMass. Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck. Now united with Schepens Eye Research Institute, Mass. Eye and Ear is the world's largest vision and hearing research center, developing new treatments and cures through discovery and innovation. Mass. Eye and Ear is a Harvard Medical School teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships. Internationally acclaimed since its founding in 1824, Mass. Eye and Ear employs full-time, board-certified physicians who offer high-quality and affordable specialty care that ranges from the routine to the very complex. U.S. News & World Report’s “Best Hospitals Survey” has consistently ranked the Mass. Eye and Ear Departments of Otolaryngology and Ophthalmology as top in the nation. For more information about life-changing care and research, or to learn how you can help, please visit MassEyeAndEar.org.

About Harvard Medical School Department of OphthalmologyThe Harvard Medical School (HMS) Department of Ophthalmology (eye.hms.harvard.edu) is one of the leading and largest academic departments of ophthalmology in the nation. More than 350 full-time faculty and trainees work at nine HMS affiliate institutions, including Massachusetts Eye and Ear, Schepens Eye Research Institute of Massachusetts Eye and Ear, Massachusetts General Hospital, Brigham and Women’s Hospital, Boston Children’s Hospital, Beth Israel Deaconess Medical Center, Joslin Diabetes Center/Beetham Eye Institute, Veterans Affairs Boston Healthcare System, VA Maine Healthcare System, and Cambridge Health Alliance. Formally established in 1871, the department has been built upon a strong and rich foundation in medical education, research, and clinical care. Through the years, faculty and alumni have profoundly influenced ophthalmic science, medicine, and literature—helping to transform the field of ophthalmology from a branch of surgery into an independent medical specialty at the forefront of science.