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New Finding Could Help Develop Test for Kidney Disease

Scientists at The University of Manchester have made an important finding that could help develop an early test for kidney disease.

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DNA Abnormalities Found in Children with Chronic Kidney Disease

A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, including DNA anomalies that have been linked to neurocognitive disorders, according to a new Columbia University Medical Center (CUMC) study.

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Family History Increases the Risk of Cardiac Arrest in Patients on Dialysis

Among dialysis patients, genetically related family members have about a 70% increased risk of cardiac arrest compared with unrelated dialysis patients. Spouses on dialysis do not have an increased risk.

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Trending Stories Report for 10 April 2015

Trending news releases with the most views in a single day. Topics include: Astronomy, Cardiology, Nephrology, Neurology, Neutrinos, oil spills, Toxicology, Cancer, and Nutrition

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New High-Throughput Screening Method May Uncover Novel Treatments for Kidney Disease

• Researchers have developed a system that could be used to identify novel drug candidates that protect the function of the kidney cells that are damaged in patients with chronic kidney disease. • One drug identified through the system effectively protected the kidney cells of rodents exposed to kidney damaging agents.

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Kidney Health Initiative Seeking Patient Input Into New Therapies for Kidney Disease

The Kidney Health Initiative (KHI) is seeking input from patients with kidney disease and their family members on future treatment options. The perspectives gathered in this new KHI project will help inform development of therapeutics and devices for kidney disease, which affects more than 20 million Americans.

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Hormone and Bone Tests May Be Indicative of Dialysis Patients’ Heart Health

• High parathyroid hormone levels and subsequent bone loss are major risk factors for worsening of coronary artery calcification in patients on dialysis.

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What to Do with Kidneys From Older Deceased Donors?

• For older patients in need of a kidney transplant, rapid transplantation from an older deceased donor is superior to delayed transplantation from a younger donor. • Kidneys from older donors do not have sufficient longevity to provide younger patients with a lifetime of kidney function, but they do have sufficient longevity to provide older patients who have a shorter life expectancy with a lifetime of kidney function.

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Study Reports Excellent Outcomes Among HIV+ Kidney Transplant Recipients

• Compared with uninfected (HIV-/HCV-) kidney transplant recipients, mono-infected HIV+ (HIV+/HCV-) recipients had similar 5-year and 10-year kidney survival rates, while HIV+ recipients co-infected with HCV (HIV+/HCV+) had worse kidney survival rates. • Patient survival among mono-infected HIV+ recipients was similar to uninfected recipients but was significantly lower for co-infected recipients.

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First National Kidney Graft Survival Study of HIV-Positive Recipients

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Kidney recipients infected only with HIV do as well as uninfected recipients, but HIV-infected recipients co-infected with hepatitis C virus have poorer outcomes.