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Prevalence of Chronic Kidney Disease in Adults Over 30 to Rise 27 Percent by 2030

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The prevalence of chronic kidney disease (CKD) will rise in the United States, according to a new report led by RTI International and published in the American Journal of Kidney Diseases during March's National Kidney Month

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 5-Mar-2015 5:00 PM EST

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Diet High In Red Meat May Make Kidney Disease Worse

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An estimated 26 million people in the United States have chronic kidney disease, which can lead to complete kidney failure. Once the kidneys fail, patients either need to undergo dialysis treatments three times a week or have a kidney transplant to remain alive.

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Why Are Kidney Patients Starting Dialysis Sooner?

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• In VA medical centers, patients started dialysis progressively earlier in the course of their kidney disease in more recent years. • There were no measurable differences in how sick patients were at the time of initiation or in the reasons for dialysis initiation to explain this trend.

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Most Patients with Chronic Kidney Disease May Experience Long-Term Pain

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• In a study of patients with pre-dialysis chronic kidney disease, most patients reported chronic pain. • More severe pain was linked with both proper and improper use of pain medications.

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A High Acid Diet May Have Negative Effects on Kidney Health

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• Among patients with chronic kidney disease, patients who consumed high acid diets were 3-times more likely to develop kidney failure than patients who consumed low acid diets. • Low acid load diets are rich in fruits and vegetables, while high acid diets contain more meats.

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Study Provides Insights on Enzyme That Helps Direct the Immune Response to Kidney Injury

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• An enzyme called heme oxygenase-1 (HO-1) affects immune cells as they travel through the body in response to kidney injury. • In mice, the absence of HO-1 leads to poor recovery after acute kidney injury.

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Simple Test Detects Increased Risks in Patients with Acute Kidney Injury

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• A simple test performed with the FDA-approved medication furosemide, along with a measurement of urine output, can predict which patients with acute kidney injury will later require dialysis. • The test could help clinicians safeguard patients’ kidney health.

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Kidney-Brain Connection May Help Drive Chronic Kidney Disease

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• Salt intake accelerated kidney scarring in rats with chronic kidney disease by activating a brain-kidney connection called the renin-angiotensin axis that interlinks the damaged kidney and brain by afferent and efferent sympathetic nerves. • Targeting these nerves reduced salt-induced kidney scarring.

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High Blood Calcium Levels Linked with Increased Risk of Premature Death in Dialysis Patients

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• Both low and high blood calcium levels, as well as high phosphorus levels, were linked with an increased risk of dying prematurely in dialysis patients, regardless of the type of dialysis. • The findings address a pending Medicare quality measure related to dialysis patients’ blood calcium levels.