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HIV, Transplantation

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Feb-2017 5:00 PM EST

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Transplant Rejection

Discovery May Help Prevent Tissue Scarring and Rejection of Transplanted Kidneys

• During rejection of a transplanted kidney, certain immune cells transform into connective tissue cells, which produce collagen and other fibers. • This transition, which is mediated by the TGF-/Smad3 signaling pathway, leads to scarring and decreased kidney function.

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salt, Blood Pressure, Chronic Kidney Disease

Limiting Salt Consumption Lowers Blood Pressure in Patients with Kidney Disease

• Receiving advice on limiting salt consumption helped kidney disease patients lower their systolic blood pressure by an average of 11 mmHg. • Limiting salt intake also reduced excess fluid retention that is common among patients with kidney disease.

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Ut Southwestern, Kidney Disease, Polycystic Kidney Disease, Autosomal Dominant Polycystic Disease, Adpkd

UT Southwestern Researchers Develop Potential Treatment for Fatal, Incurable Kidney Disease

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Researchers at UT Southwestern Medical Center, working with a California biotech firm, have developed a potential drug to treat polycystic kidney disease – an incurable genetic disease that often leads to end-stage kidney failure

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Fragile X Syndrome, Steven Tyler's Janie's Fund Wins Big, Untreated Water Making Our Kids Sick, and More in the Children's Health News Source

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Heart-Shaped Cells, The Power of Aspirin, Stem Cells Transplants and More in the Cancer News Source

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Language Barriers, Kidney Transplantation

Language Barriers May Interfere with Access to Kidney Transplantation

• Higher degrees of linguistic isolation were linked with a lower likelihood of transitioning from inactive to active status on the kidney transplant waiting list and with incomplete transplant evaluations. • The association of linguistic isolation appeared to be most influential among Hispanic transplant candidates.

Science

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Research, Kidneys, Kidney, Animal Testing, human testing, test subjects, Models, Model, Medicine, Biomedical Engineering, Biomedicine, Drugs, studying drugs, Drug Study, Tissue, Tissue Engineering, Organs, Drug Screening, drug candidates , Cells, Cell Culture, Glomerulus, renal drug toxicity, Drug Toxicity, glomerular filtration, human cells, Binghamton, Binghamton

Researchers Develop Device That Emulates Human Kidney Function and Could Replace Animal, Human Testing

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Instead of running tests on live kidneys, researchers at Binghamton, University State University of New York have developed a model kidney for working out the kinks in medicines and treatments. Developed by Assistant Professor Gretchen Mahler and Binghamton biomedical engineering alumna Courtney Sakolish PhD ’16, the reusable, multi-layered and microfluidic device incorporates a porous growth substrate, with a physiological fluid flow, and the passive filtration of the capillaries around the end of a kidney, called the glomerulus, where waste is filtered from blood.

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American Society Of Nephrology, Department of Veterans Affairs, Kidney Diseases

The American Society of Nephrology Partners with the Department of Veterans Affairs to Advance Best Practices and Approaches to Kidney Disease

The American Society of Nephrology (ASN) is pleased to partner with the Department of Veterans Affairs (VA) to host the upcoming Kidney Innovation Summit. The Summit will take place at the Booz Allen Hamilton Center for Innovation in Washington, DC on February 9 – 10, 2017.

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Foods That Protect Against Heart Disease, Sitting Not Linked to Incident Diabetes, New Studies on Suppressing the Urge to Eat, and More in the Obesity News Source

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Penn Genetics Researcher Receives Grant From Pharmaceutical Consortium to Study Diabetic Kidney Disease

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Katalin Susztak, MD, PhD, an associate professor of Medicine and Genetics in the Perelman School of Medicine at the University of Pennsylvania, has received a $3 million grant from a consortium of pharmaceutical companies to identify genes and other characteristics that are signs of rapid decline in kidney function in patients with diabetic kidney disease.

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Dialysis, dialysis blood tests, Blood Testing, Pathology, BCP, BCG, medical diagnosis, Medical Diagnostics, David Bruns, UVA, University Of Virginia, University of Virginia School of Medicine, UVA School of Medicine, Min Yu, Nephrology, Nutritional Supplementation, Healthcare, Healthcare Costs, Medical Costs, Virginia Commonwealth University, VCU, VCU School o

Troubling Inconsistency Found in Dialysis Blood Testing Methods

A blood test used to determine the health and well-being of dialysis patients produces worryingly inconsistent results depending on which testing method is used, new research reveals.

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Sodium, Heart Disease, Kidney Disease

Skin Sodium Content Linked to Heart Problems in Patients with Kidney Disease

• Elevated sodium content in the skin correlates closely with left ventricular hypertrophy in patients with chronic kidney disease.

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Kidney Function, Stoke

Kidney Function in Stroke Patients Associated with Short-Term Outcomes

A routine blood test that measures kidney function can be a valuable predictor of short-term outcomes for stroke patients, according to a study led by a neurologist at Wake Forest Baptist Medical Center.

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Depression, Dialysis

Depression Is Under-Treated in Patients Receiving Chronic Dialysis

• A new study found that patients on chronic hemodialysis with depression are frequently not interested in modifying or initiating anti-depressant treatment. Kidney specialists caring for these patients are often unwilling to modify or initiate anti-depressant therapy even when patients are willing to accept recommendations from nurses to do so

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DiGeorge Syndrome Kidney Problems May Be Caused By Missing Gene

A research team led by Columbia University has discovered that loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, solving a 60-year-old medical mystery.

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kidney function decline

Low Levels of Circulating Protein Linked to Kidney Function Decline

• Decreased blood levels of a protein called soluble klothos were linked with an increased likelihood of experiencing kidney function decline in a group elderly well-functioning adults.

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Kidney Diseases, Gao, American Society Of Nephrology, NIH, Medicare ESRD, Research Funding

American Society of Nephrology Welcomes GAO Report Confirming Urgent Need for Greater Research Funding

Report Details Imbalance between Kidney Disease Research and Health Impact.

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National Blood Donor Month, blood donor, Blood Donors, UCLA Blood & Platelet Center, UCLA health, Organ Transplantation, Liver Transplant, Liver Transplantation, Kidney Transplant, Kidney Transplantation, kidney and liver transplant

Blood Donors of Many Colors Pool Precious Resource to Save Woman’s Life

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Last year, Shirley Polk’s life changed forever. On Friday, it changed again, thanks to a meeting she had with 15 strangers who helped save her life. Last September, the 67-year old, whose liver and kidney suddenly failed after she developed acute autoimmune disease, received a transplant of both organs at Reagan UCLA Medical Center. On Jan. 13, at an event arranged by UCLA, she met 15 of the 59 strangers whose blood donations made possible the transplant surgeries that saved her life. Thanks to her donors’ generosity, Polk was transfused with 32 units of whole blood, 27 units of plasma and 11 units of platelets.

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Kidney Disease, Healthcare Costs, Out-of-Pocket Costs

Kidney Disease Patients Have Higher Out-of-Pocket Costs than Stroke and Cancer Patients

Patients who have chronic kidney disease but are not on dialysis have higher out-of-pocket healthcare expenses than even stroke and cancer patients, according to a study published in BMC Nephrology.







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