Mesenchymal Stem Cells in Wound Healing: A Bibliometric Analysis as a Powerful Research Tool

Newswise — Bibliographic analysis is still very rarely used in experimental basic study papers. The comprehensive bibliometric analysis of scientific literature on research progress and challenges in stem cell therapy for diabetic chronic wounds, which was conducted in the work of Shi et al can be a case study and a source of valuable information for writing reviews and experimental papers in this field. Basic experimental studies on a role of mesenchymal stem cells (MSCs) in wound healing that are published in 2023-2024, such as Zhang et al in 2023, Hu et al in 2023, Wang et al in 2023 are certainly also subjects for applying this powerful tool to analyze current research, challenges and perspectives in this field. This is due to the fact that these studies have addressed a great variety of aspects of the application of MSCs for the treatment of chronic wounds, such as using both the cells themselves and their various products: Sponges, hydrogels, exosomes, and genetic constructions. Such a wide variety of directions in the field of study and biomedical application of MSCs requires a deep understanding of the current state of research in this area, which can be provided by bibliometric analysis. Thus, the use of such elements of bibliographic analysis as publication count by year and analysis of top-10 keywords calculated independently or cited from bibliometric analysis studies can be safely recommended for every basic study manuscripts, primarily for the “Introduction” section, and review.

Key Words: Bibliometric analysis; Mesenchymal stem cells; Wound healing; Tissue engineering; Dressing; Hydrogels; Matrix; Exosomes

Core Tip: Bibliographic analysis is still very rarely used in basic studies. Meanwhile, it is a very effective tool to better understand the development of the chosen research area and to analyze the data more broadly, as it is perfectly demonstrated in the work of Shi et al in 2024 and in comparisons with basic studies on a role of mesenchymal stem cells in wound healing published. Such elements of bibliographic analysis as publication count by year and analysis of top-10 keywords can be safely recommended for using in every basic study manuscripts.

• Citation: Voinova VV, Vasina DV, Bonartsev AP. Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool. World J Stem Cells 2024; 16(9): 827-831
• URL: https://www.wjgnet.com/1948-0210/full/v16/i9/827.htm
• DOI: https://dx.doi.org/10.4252/wjsc.v16.i9.827