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Future Breast Imaging and Biopsy Are Not Eliminated After Mastectomy
Information Critical for Medical Decision-Making, Say Mount Sinai Researchers
Newswise — (New York, October 9, 2018) The proportion of breast cancer patients who are eligible for breast conservation therapy, yet opt for mastectomy, is increasing, for reasons that include the desire to eliminate future screening and/or biopsy of the remaining breast tissue. A new study led by researchers at the Icahn School of Medicine at Mount Sinai has determined that having a mastectomy does not completely eliminate the need for further breast imaging studies.
These results, published online in September in the Annals of Surgical Oncology, can help guide breast cancer patients and their physicians in their medical and surgical decision-making.
The study, titled “Defining the Need for Imaging and Biopsy After Mastectomy,” is a retrospective review of all mastectomy cases, either one-sided or both sides, performed at The Mount Sinai Hospital’s Dubin Breast Center. Post-mastectomy imaging and biopsy rates were determined. To the researchers’ knowledge, this is the first study to describe the incidence and need for postoperative imaging and biopsy for patients who undergo mastectomy.
“Autonomy and choice in treatment are encouraged, and can be empowering for patients. But decision-making can also result in anxiety, fear, and distress. Some patients might choose more extensive surgery with the hope that this will reduce the need for breast imaging and biopsy later, when in fact this is not necessarily the medically beneficial course,” said Soojin Ahn, MD, Assistant Professor of Breast Surgery, Mount Sinai St. Luke’s.
The researchers identified 185 unilateral (one side) and 200 bilateral (both sides) mastectomy cases performed for breast cancer between 2009 and 2015. The average follow-up period was 30 months (the number of months ranged from 3 to 75). Of the 185 unilateral patients, 19 (10 percent) underwent imaging on that side (all ultrasounds) for concerning physical examination findings, 11 (6 percent) underwent biopsy, and two (1 percent) showed malignant findings. Of the 200 bilateral mastectomy patients, 31 (15.5 percent) required imaging (29 ultrasounds and 2 MRIs), with 76 percent of the ultrasounds performed on the side with previous cancer. Subsequently, 16 (8 percent) of these patients had biopsy, with 11 (69 percent) of the 16 biopsies performed on the same side as the previous cancer. Three (1.5 percent) of the biopsies done on this side demonstrated malignancy, whereas all five biopsies performed on the other side were benign.
Dr. Ahn and her colleagues concluded that for 10 percent to 15.5 percent of patients who undergo either a unilateral or bilateral mastectomy, subsequent imaging is required, and 6 to 8 percent ultimately undergo biopsy. The rate of malignancy was found to be low, approximately 1 percent. Nevertheless, enough cases were identified that the researchers concluded that mastectomies do not eliminate the need for imaging and biopsy.
“This information is critical for patient understanding and decision-making,” said Elisa Port, MD, FACS, Chief of Breast Surgery and Co-Director of the Dubin Breast Cancer. “Physicians and their patients should make their surgical treatment decisions after careful consideration of various clinical factors and realistic expectations for post-operative follow up.”
About Mount Sinai Health System
The Mount Sinai Health System is New York City’s largest integrated delivery system encompassing seven hospital campuses, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai’s vision is to produce the safest care, the highest quality, the highest satisfaction, the best access and the best value of any health system in the nation. The System includes approximately 6,600 primary and specialty care physicians; 11 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report’s “Best Medical Schools”, aligned with a U.S. News & World Report’s “Honor Roll” Hospital, it is ranked as a leading medical school for National Institutes of Health funding, and among the top 10 most innovative research institutions as ranked by the journal Nature in its Nature Innovation Index. This reflects a special level of excellence in education, clinical practice, and research. The Mount Sinai Hospital is ranked No. 18 on U.S. News & World Report’s “Honor Roll” of top U.S. hospitals; it is one of the nation’s top 20 hospitals in Cardiology/Heart Surgery, Gastroenterology/GI Surgery, Geriatrics, Nephrology, and Neurology/Neurosurgery, and in the top 50 in six other specialties in the 2018-2019 “Best Hospitals” issue. Mount Sinai’s Kravis Children’s Hospital also is ranked nationally in five out of ten pediatric specialties by U.S. News & World Report. The New York Eye and Ear Infirmary of Mount Sinai is ranked 11th nationally for Ophthalmology and 44th for Ear, Nose, and Throat, while Mount Sinai Beth Israel, Mount Sinai St. Luke’s and Mount Sinai West are ranked regionally. For more information, visit http://www.mountsinai.org/, or find Mount Sinai on Facebook, Twitter and YouTube.
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